A Pilot Screen of a Novel Peptide Hormone Library Identified Candidate GPR83 Ligands

The role of the neuropeptide PEN receptor, GPR83, in the reward pathway: Relationship to sex-differences

(2019) Amanda K. Fakira et al.   NEUROPHARMACOLOGY

Novel approaches leading towards peptide GPCR de‐orphanisation

(2019) Alexander S. Hauser et al.   BRITISH JOURNAL OF PHARMACOLOGY

Placenta-specific 9, a putative secretory protein, induces G2/M arrest and inhibits the proliferation of human embryonic hepatic cells

(2018) Cong Ouyang et al.   BIOSCIENCE REPORTS

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases

(2017) Carla S. B. Viegas et al.   PLoS One

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

(2016) Åsa Segerstolpe et al.   Cell Metabolism

Identification of GPR83 as the receptor for the neuroendocrine peptide PEN

(2016) Ivone Gomes et al.   Science Signaling

Identification of GPR83 as the receptor for the neuroendocrine peptide PEN

(2016) Ivone Gomes et al.   Science Signaling

Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83

(2016) Anne Müller et al.   PLoS One

Adipocyte-derived PAMM suppresses macrophage inflammation by inhibiting MAPK signalling

(2015) F. Guo et al.   BIOCHEMICAL JOURNAL

Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1

(2015) Maria Belen Lopez et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Constitutive Activity among Orphan Class-A G Protein Coupled Receptors

(2015) Adam L. Martin et al.   PLoS One

SDHAF4 Promotes Mitochondrial Succinate Dehydrogenase Activity and Prevents Neurodegeneration

(2014) Jonathan G. Van Vranken et al.   Cell Metabolism

Esophageal cancer-related gene-4 (ECRG4) interactions with the innate immunity receptor complex

(2014) Sonia Podvin et al.   INFLAMMATION RESEARCH

C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma

(2014) Stefan Salcher et al.   Molecular Cancer

Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome

(2014) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

(2013) Anne Müller et al.   PLoS One

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

(2013) Timo D. Müller et al.   Nature Communications

Posttranslational Modifications of Proopiomelanocortin in Vertebrates and Their Biological Significance

(2013) Akiyoshi Takahashi et al.   Frontiers in Endocrinology

Mutations in C4orf26, Encoding a Peptide with In Vitro Hydroxyapatite Crystal Nucleation and Growth Activity, Cause Amelogenesis Imperfecta

(2012) David A. Parry et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Attenuated stress-evoked anxiety, increased sucrose preference and delayed spatial learning in glucocorticoid-induced receptor-deficient mice

(2012) L. E. Vollmer et al.   GENES BRAIN AND BEHAVIOR

Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin

(2012) Jeffrey S. Dubins et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

Atypical angiopoietin-like protein that regulates ANGPTL3

(2012) F. Quagliarini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a new mouse sperm acrosome-associated protein

(2012) Joanna Korfanty et al.   REPRODUCTION

A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma

(2011) Lin-wei Li et al.   BMC CANCER

Novel hormone-regulated genes in visceral adipose tissue: cloning and identification of proinflammatory cytokine-like mouse and human MEDA-7: implications for obesity, insulin resistance and the metabolic syndrome

(2011) H. Zhang et al.   DIABETOLOGIA

Adipolin/C1qdc2/CTRP12 Protein Functions as an Adipokine That Improves Glucose Metabolism

(2011) Takashi Enomoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Applying label-free dynamic mass redistribution technology to frame signaling of G protein–coupled receptors noninvasively in living cells

(2011) Ralf Schröder et al.   Nature Protocols

Deorphanization of Novel Peptides and Their Receptors

(2010) Akihiko Ozawa et al.   AAPS Journal

Identification of a new secretory factor, CCDC3/Favine, in adipocytes and endothelial cells

(2009) Sachiko Kobayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evolutionary Sequence Modeling for Discovery of Peptide Hormones

(2009) Kemal Sonmez et al.   PLoS Computational Biology

Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

(2008) H. Lin et al.   SCIENCE