Identification of GPR83 as the receptor for the neuroendocrine peptide PEN

G Protein–Coupled Receptor Heteromers

(2016) Ivone Gomes et al.   Annual Review of Pharmacology and Toxicology

Constitutive Activity among Orphan Class-A G Protein Coupled Receptors

(2015) Adam L. Martin et al.   PLoS One

Endothelin-converting enzyme 2 differentially regulates opioid receptor activity

(2014) A Gupta et al.   BRITISH JOURNAL OF PHARMACOLOGY

Opioid Receptor Function Is Regulated by Post-endocytic Peptide Processing

(2014) Achla Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ProSAAS-Derived Peptides Are Differentially Processed and Sorted in Mouse Brain and AtT-20 Cells

(2014) Jonathan H. Wardman et al.   PLoS One

G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

(2013) Anne Müller et al.   PLoS One

GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding

(2013) I. Gomes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

(2013) Timo D. Müller et al.   Nature Communications

Attenuated stress-evoked anxiety, increased sucrose preference and delayed spatial learning in glucocorticoid-induced receptor-deficient mice

(2012) L. E. Vollmer et al.   GENES BRAIN AND BEHAVIOR

AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II

(2011) Raphael Rozenfeld et al.   EMBO JOURNAL

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

(2011) Michael J. Krashes et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of NPY type 5 receptors induces a long-lasting increase in spontaneous GABA release from cerebellar inhibitory interneurons

(2011) C. J. Dubois et al.   JOURNAL OF NEUROPHYSIOLOGY

G Protein-Coupled Receptor Heteromerization: A Role in Allosteric Modulation of Ligand Binding

(2011) I. Gomes et al.   MOLECULAR PHARMACOLOGY

ProSAAS-Derived Peptides are Colocalized with Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake

(2011) Jonathan H. Wardman et al.   PLoS One

Inflammation in vivo is modulated by GPR83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cells

(2010) W Hansen et al.   GENES AND IMMUNITY

Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins

(2010) Lloyd D. Fricker   Molecular BioSystems

Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration

(2010) A. Gupta et al.   Science Signaling

Novel endogenous peptide agonists of cannabinoid receptors

(2009) Ivone Gomes et al.   FASEB JOURNAL

Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis

(2009) Xin Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL

Gpr83 expression is not required for the maintenance of intestinal immune homeostasis and regulation of T-cell-dependent colitis

(2008) Christy Toms et al.   IMMUNOLOGY

Peptidomics ofCpefat/fatmouse brain regions: implications for neuropeptide processing

(2008) Xin Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Mass spectrometry-based discovery of circadian peptides

(2008) N. G. Hatcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth

(2008) K. D. Bromberg et al.   SCIENCE