G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

Ice breaking in GPCR structural biology

(2012) Qiang Zhao et al.   ACTA PHARMACOLOGICA SINICA

The role of the extracellular loops of the CGRP receptor, a family B GPCR

(2012) James Barwell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Lifting the lid on GPCRs: the role of extracellular loops

(2012) M Wheatley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structure-Based Design in the GPCR Target Space

(2012) M. Kontoyianni et al.   CURRENT MEDICINAL CHEMISTRY

Transcriptional Response to Calcium-Sensing Receptor Stimulation

(2012) Gerald Thiel et al.   ENDOCRINOLOGY

Structure-based drug screening for G-protein-coupled receptors

(2012) Brian K. Shoichet et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

New insights from structural biology into the druggability of G protein-coupled receptors

(2012) Jonathan S. Mason et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models

(2011) Catherine L Worth et al.   BMC BIOINFORMATICS

Guide to Receptors and Channels (GRAC), 5th edition

(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacological characterization of zinc and copper interaction with the human alpha1A-adrenoceptor

(2011) Justyna Ciolek et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

New Pathogenic Thyrotropin Receptor Mutations Decipher Differentiated Activity Switching at a Conserved Helix 6 Motif of Family A GPCR

(2011) Heike Biebermann et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ligand discovery from a dopamine D3 receptor homology model and crystal structure

(2011) Jens Carlsson et al.   Nature Chemical Biology

A New Phenotype of Nongoitrous and Nonautoimmune Hyperthyroidism Caused by a Heterozygous Thyrotropin Receptor Mutation in Transmembrane Helix 6

(2010) Franziska Winkler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

(2010) Michael P. Bokoch et al.   NATURE

Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation

(2010) M.C. Peeters et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Thyrotropin and Homologous Glycoprotein Hormone Receptors: Structural and Functional Aspects of Extracellular Signaling Mechanisms

(2009) Gunnar Kleinau et al.   ENDOCRINE REVIEWS

Heterodimerization of Hypothalamic G-Protein-Coupled Receptors Involved in Weight Regulation

(2009) Anne Rediger et al.   Obesity Facts

Comparative Sequence and Structural Analyses of G-Protein-Coupled Receptor Crystal Structures and Implications for Molecular Models

(2009) Catherine L. Worth et al.   PLoS One

Discovery of New GPCR Biology: One Receptor Structure at a Time

(2009) Michael A. Hanson et al.   STRUCTURE

Multiple Switches in G Protein-Coupled Receptor Activation

(2009) Shivani Ahuja et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ligand binding and micro-switches in 7TM receptor structures

(2009) Rie Nygaard et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Molecular mechanism of Zn2+agonism in the extracellular domain of GPR39

(2008) Laura Storjohann et al.   FEBS LETTERS

Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling

(2008) Jean-Pierre Vilardaga et al.   Nature Chemical Biology

New G-protein-coupled receptor crystal structures: insights and limitations

(2008) B KOBILKA et al.   TRENDS IN PHARMACOLOGICAL SCIENCES