Mitochondrion-Directed Nanoparticles Loaded with a Natural Compound and a microRNA for Promoting Cancer Cell Death via the Modulation of Tumor Metabolism and Mitochondrial Dynamics

Ellagic acid attenuates liver toxicity induced by valproic acid in rats

(2020) Noha F. Abdelkader et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

MALAT1 Up-Regulator Polydatin Protects Brain Microvascular Integrity and Ameliorates Stroke Through C/EBPβ/MALAT1/CREB/PGC-1α/PPARγ Pathway

(2019) Wenchen Ruan et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog

(2019) Nan Yao et al.   Cell Death & Disease

miR-125b suppresses oral oncogenicity by targeting the anti-oxidative gene PRXL2A

(2019) Yi-Fen Chen et al.   Redox Biology

RKI-1447 suppresses colorectal carcinoma cell growth via disrupting cellular bioenergetics and mitochondrial dynamics

(2019) Liyi Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA miR-31 targets SIRT3 to disrupt mitochondrial activity and increase oxidative stress in oral carcinoma

(2019) Yu-Yu Kao et al.   CANCER LETTERS

Improving the anticancer effect of afatinib and microRNA by using lipid polymeric nanoparticles conjugated with dual pH-responsive and targeting peptides

(2019) Shu-Ting Hong et al.   JOURNAL OF NANOBIOTECHNOLOGY

PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells

(2019) Chunle Zhao et al.   Frontiers in Pharmacology

pH‐Responsive PEG‐Shedding and Targeting Peptide‐Modified Nanoparticles for Dual‐Delivery of Irinotecan and microRNA to Enhance Tumor‐Specific Therapy

(2019) Vivian Juang et al.   Small

FOXO1, a Potential Therapeutic Target, Regulates Autophagic Flux, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Human Cholangiocarcinoma QBC939 Cells

(2018) Wei He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effect of Mst1 on Endometriosis Apoptosis and Migration: Role of Drp1-Related Mitochondrial Fission and Parkin-Required Mitophagy

(2018) Qingdong Zhao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hepatic peroxisome proliferator-activated receptor γ coactivator 1β drives mitochondrial and anabolic signatures that contribute to hepatocellular carcinoma progression in mice

(2018) Elena Piccinin et al.   HEPATOLOGY

Zinc oxide nanoparticles induce toxicity in CAL 27 oral cancer cell lines by activating PINK1/Parkin-mediated mitophagy

(2018) Jianfeng Wang et al.   International Journal of Nanomedicine

Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells

(2018) Shuyan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab9-dependent autophagy is required for the IGF-IIR triggering mitophagy to eliminate damaged mitochondria

(2018) Chih-Yang Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pomegranate polyphenols and urolithin A inhibit α-glucosidase, dipeptidyl peptidase-4, lipase, triglyceride accumulation and adipogenesis related genes in 3T3-L1 adipocyte-like cells

(2018) Francisco Les et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cholesterol-lowering effects of dietary pomegranate extract and inulin in mice fed an obesogenic diet

(2018) Jieping Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Tanshinone IIA regulates colorectal cancer apoptosis via attenuation of Parkin‑mediated mitophagy by suppressing AMPK/Skp2 pathways

(2018) Lili He et al.   Molecular Medicine Reports

Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways

(2018) Chen Shi et al.   Redox Biology

Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways

(2018) Runjie Wei et al.   CELL STRESS & CHAPERONES

Effects of Polyphenols on Thermogenesis and Mitochondrial Biogenesis

(2018) Tanila Wood dos Santos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CerS6 regulates cisplatin resistance in oral squamous cell carcinoma by altering mitochondrial fission and autophagy

(2018) Shengjiao Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

(2018) Anthea Di Rita et al.   Nature Communications

Ellagic acid antagonizes Bnip3-mediated mitochondrial injury and necrotic cell death of cardiac myocytes

(2017) Abhinav Dhingra et al.   FREE RADICAL BIOLOGY AND MEDICINE

HOTAIR regulates HK2 expression by binding endogenous miR-125 and miR-143 in oesophageal squamous cell carcinoma progression

(2017) Jian Ma et al.   Oncotarget

Nanotechnology inspired tools for mitochondrial dysfunction related diseases

(2016) Ru Wen et al.   ADVANCED DRUG DELIVERY REVIEWS

Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated cancer-specific cytotoxicity

(2016) Chengyong He et al.   BIOMATERIALS

Delivery of drugs and macromolecules to the mitochondria for cancer therapy

(2016) Phong Lu et al.   JOURNAL OF CONTROLLED RELEASE

Potential Anticancer Effects of Polyphenols from Chestnut Shell Extracts: Modulation of Cell Growth, and Cytokinomic and Metabolomic Profiles

(2016) Angela Sorice et al.   MOLECULES

Glucose, Lactate and Glutamine but not Glutamate Support Depolarization-Induced Increased Respiration in Isolated Nerve Terminals

(2016) Michaela C. Hohnholt et al.   NEUROCHEMICAL RESEARCH

Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting

(2016) Ji-Young Kim et al.   Oncotarget

miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function

(2016) Maude Giroud et al.   Molecular Metabolism

Sanguisorba officinalis L synergistically enhanced 5-fluorouracil cytotoxicity in colorectal cancer cells by promoting a reactive oxygen species-mediated, mitochondria-caspase-dependent apoptotic pathway

(2016) Meng-ping Liu et al.   Scientific Reports

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

(2015) Yunching Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response

(2015) Lei Jiang et al.   BIOMATERIALS

Kinsenoside-mediated lipolysis through an AMPK-dependent pathway in C3H10T1/2 adipocytes

(2015) Kur-Ta Cheng et al.   PHYTOMEDICINE

PEG-detachable lipid–polymer hybrid nanoparticle for delivery of chemotherapy drugs to cancer cells

(2014) Jiang-bo Du et al.   ANTI-CANCER DRUGS

Liposomal delivery of nucleic acid-based anticancer therapeutics: BP-100-1.01

(2014) Ana Tari Ashizawa et al.   Expert Opinion on Drug Delivery

Overexpression of microRNA-125b sensitizes human hepatocellular carcinoma cells to 5-fluorouracil through inhibition of glycolysis by targeting hexokinase II

(2014) JIAN-XIN JIANG et al.   Molecular Medicine Reports

Enhancing endosomal escape for nanoparticle mediated siRNA delivery

(2014) Da Ma   Nanoscale

Ellagic Acid Suppresses Lipid Accumulation by Suppressing Early Adipogenic Events and Cell Cycle Arrest

(2014) Mi-Seon Woo et al.   PHYTOTHERAPY RESEARCH

The clinical utility of two human portable blood glucose meters in canine and feline practice

(2014) Asuka Domori et al.   VETERINARY CLINICAL PATHOLOGY

Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats

(2012) Sunil K. Panchal et al.   EUROPEAN JOURNAL OF NUTRITION

BBA, a Derivative of 23-Hydroxybetulinic Acid, Potently Reverses ABCB1-Mediated Drug Resistance in Vitro and in Vivo

(2012) Dong-Mei Zhang et al.   MOLECULAR PHARMACEUTICS

Safety assessment of ellagic acid, a food additive, in a subchronic toxicity study using F344 rats

(2007) M. Tasaki et al.   FOOD AND CHEMICAL TOXICOLOGY