Improving the anticancer effect of afatinib and microRNA by using lipid polymeric nanoparticles conjugated with dual pH-responsive and targeting peptides

Co-expression and prognostic significance of putative CSC markers CD44, CD133, wild-type EGFR and EGFRvIII in metastatic colorectal cancer

(2019) Said Abdullah Khelwatty et al.   Oncotarget

Tacrolimus-loaded methoxy poly(ethylene glycol)-block-poly(D,L)-lactic–co-glycolic acid micelles self-assembled in aqueous solution for treating cornea immune rejection after allogenic penetrating keratoplasty in rats

(2019) Dong Liu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Tyrosine Kinase Inhibitor Gold Nanoconjugates for the Treatment of Non-Small Cell Lung Cancer

(2019) Alexander M. Cryer et al.   ACS Applied Materials & Interfaces

Investigation of PLGA nanoparticles in conjunction with nuclear localization sequence for enhanced delivery of antimiR phosphorothioates in cancer cells in vitro

(2019) Shipra Malik et al.   JOURNAL OF NANOBIOTECHNOLOGY

The theranostic efficiency of tumor-specific, pH-responsive, peptide-modified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles

(2018) Xiu-Chai Zheng et al.   International Journal of Nanomedicine

Anti epidermal growth factor receptor therapy in small bowel adenocarcinoma

(2018) Rosa Falcone et al.   MEDICINE

Drug resistance and new therapies in colorectal cancer

(2018) Kevin Van der Jeught et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A novel MUC1 aptamer-modified PLGA-epirubicin-PβAE-antimir-21 nanocomplex platform for targeted co-delivery of anticancer agents in vitro and in vivo

(2018) Amirhossein Bahreyni et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Evaluation of the drug loading capacity of different lipid nanoparticle dispersions by passive drug loading

(2017) Karin M. Rosenblatt et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

High drug-loading nanomedicines: progress, current status, and prospects

(2017) Shihong Shen et al.   International Journal of Nanomedicine

Afatinib Decreases P-Glycoprotein Expression to Promote Adriamycin Toxicity of A549T Cells

(2017) Yan Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Preventive effect of kampo medicine (hangeshashin-to, TJ-14) plus minocycline against afatinib-induced diarrhea and skin rash in patients with non-small cell lung cancer

(2017) Masao Ichiki et al.   OncoTargets and Therapy

Recent developments in the treatment of metastatic colorectal cancer

(2017) Jonathan M. Loree et al.   Therapeutic Advances in Medical Oncology

Targeted deletion of miR-139-5p activates MAPK, NF-κB and STAT3 signaling and promotes intestinal inflammation and colorectal cancer

(2016) Fangyuan Zou et al.   FEBS Journal

Global patterns and trends in colorectal cancer incidence and mortality

(2016) Melina Arnold et al.   GUT

miR-139-5p sensitizes colorectal cancer cells to 5-fluorouracil by targeting NOTCH-1

(2016) Heyong Liu et al.   PATHOLOGY RESEARCH AND PRACTICE

HER-2 inhibition in gastric and colorectal cancers: tangible achievements, novel acquisitions and future perspectives

(2016) Valentina Fanotto et al.   Oncotarget

miR-139-5p Inhibits the Epithelial-Mesenchymal Transition and Enhances the Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating BCL2

(2016) Qingguo Li et al.   Scientific Reports

Next-Generation Covalent Irreversible Kinase Inhibitors in NSCLC: Focus on Afatinib

(2015) Vera Hirsh   BIODRUGS

Acquired resistance to anti-EGFR mAb ICR62 in cancer cells is accompanied by an increased EGFR expression, HER-2/HER-3 signalling and sensitivity to pan HER blockers

(2015) Said A Khelwatty et al.   BRITISH JOURNAL OF CANCER

Functionalized gold nanoparticles improve afatinib delivery into cancer cells

(2015) Sílvia Castro Coelho et al.   Expert Opinion on Drug Delivery

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials

(2015) James Chih-Hsin Yang et al.   LANCET ONCOLOGY

HER2 Activating Mutations Are Targets for Colorectal Cancer Treatment

(2015) S. M. Kavuri et al.   Cancer Discovery

The pan-HER family tyrosine kinase inhibitor afatinib overcomes HER3 ligand heregulin-mediated resistance to EGFR inhibitors in non-small cell lung cancer

(2015) Kimio Yonesaka et al.   Oncotarget

Afatinib and its encapsulated polymeric micelles inhibits HER2-overexpressed colorectal tumor cell growth in vitro and in vivo

(2015) Siao-Syun Guan et al.   Oncotarget

Neuropilin regulation of angiogenesis: Figure 1

(2014) Anastasia Lampropoulou et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Afatinib in the treatment of breast cancer

(2014) Sara A Hurvitz et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Intravenously administered nanoparticles increase survival following blast trauma

(2014) M. M. Lashof-Sullivan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: A review

(2013) Kunn Hadinoto et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Prognostic significance and targeting of HER family in colorectal cancer 

(2013) Helmout Modjtahedi   Frontiers in Bioscience-Landmark

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Tumor-Penetrating Peptides

(2013) Tambet Teesalu et al.   Frontiers in Oncology

MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor

(2012) Ke Shen et al.   BIOCHEMICAL PHARMACOLOGY

Moonlighting Peptides with Emerging Function

(2012) Jonathan G. Rodríguez Plaza et al.   PLoS One

The efficiency of tumor-specific pH-responsive peptide-modified polymeric micelles containing paclitaxel

(2011) Bing-Xiang Zhao et al.   BIOMATERIALS

HER2 Interacts With CD44 to Up-regulate CXCR4 via Epigenetic Silencing of microRNA-139 in Gastric Cancer Cells

(2011) Wei Bao et al.   GASTROENTEROLOGY

The pH sensitivity of histidine-contain- ing lytic peptides

(2009) Zhigang Tu et al.   JOURNAL OF PEPTIDE SCIENCE

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

(2009) T. Teesalu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform

(2008) Liangfang Zhang et al.   ACS Nano

Effect of PLGA as a polymeric emulsifier on preparation of hydrophilic protein-loaded solid lipid nanoparticles

(2008) ShuYu Xie et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Studies on anticancer activities of antimicrobial peptides

(2007) David W. Hoskin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES