Hydrogel-Based Localized Nonviral Gene Delivery in Regenerative Medicine Approaches—An Overview
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Title
Hydrogel-Based Localized Nonviral Gene Delivery in Regenerative Medicine Approaches—An Overview
Authors
Keywords
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Journal
Pharmaceutics
Volume 12, Issue 8, Pages 752
Publisher
MDPI AG
Online
2020-08-11
DOI
10.3390/pharmaceutics12080752
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Note: Only part of the references are listed.- Effective naked plasmid DNA delivery into stem cells by microextrusion-based transient-transfection system for in situ cardiac repair
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- (2019) Hasan Uludag et al. Frontiers in Bioengineering and Biotechnology
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- (2019) Norman F. Truong et al. Acta Biomaterialia
- Inhibition of Senescence‐Associated Genes Rb1 and Meis2 in Adult Cardiomyocytes Results in Cell Cycle Reentry and Cardiac Repair Post–Myocardial Infarction
- (2019) Perwez Alam et al. Journal of the American Heart Association
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- (2019) J. Carthew et al. Acta Biomaterialia
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- (2018) Ganjun Feng et al. Advanced Healthcare Materials
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- (2012) Talar Tokatlian et al. Acta Biomaterialia
- The attenuation of restenosis following arterial gene transfer using carbon nanotube coated stent incorporating TAT/DNAAng1+Vegf nanoparticles
- (2012) Arghya Paul et al. BIOMATERIALS
- Nanostructured PEG-based hydrogels with tunable physical properties for gene delivery to human mesenchymal stem cells
- (2012) Yan Li et al. BIOMATERIALS
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- Gene therapy vectors with enhanced transfection based on hydrogels modified with affinity peptides
- (2011) Jaclyn A. Shepard et al. BIOMATERIALS
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- (2011) Tomoya Manaka et al. BIOMATERIALS
- Hydrogel design for supporting neurite outgrowth and promoting gene delivery to maximize neurite extension
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- Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery
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- (2009) T. Deuse et al. CIRCULATION
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- (2009) Hongshan Zhong et al. JOURNAL OF VASCULAR SURGERY
- Heterologous expression and molecular characterization of the NAD(P)H:acceptor oxidoreductase (FerB) of Paracoccus denitrificans
- (2009) Radek Tesařík et al. PROTEIN EXPRESSION AND PURIFICATION
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