- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular Biology of Osteosarcoma
Authors
Keywords
-
Journal
Cancers
Volume 12, Issue 8, Pages 2130
Publisher
MDPI AG
Online
2020-08-03
DOI
10.3390/cancers12082130
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Key genes with prognostic values in suppression of osteosarcoma metastasis using comprehensive analysis
- (2020) Mi Li et al. BMC CANCER
- Cabozantinib in patients with advanced Ewing sarcoma or osteosarcoma (CABONE): a multicentre, single-arm, phase 2 trial
- (2020) Antoine Italiano et al. LANCET ONCOLOGY
- Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
- (2020) Isidro Cortés-Ciriano et al. NATURE GENETICS
- CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets
- (2020) Jordan L Kohlmeyer et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem
- (2020) Isabelle Corre et al. Cells
- TP53-Deficient Angiosarcoma Expression Profiling in Rat Model
- (2020) Urszula Smyczyńska et al. Cancers
- MicroRNA-Based Diagnosis and Treatment of Metastatic Human Osteosarcoma
- (2019) Ryo Sasaki et al. Cancers
- Osteosarcoma without prior retinoblastoma related to RB1 low‐penetrance germline pathogenic variants: A novel type of RB1 ‐related hereditary predisposition syndrome?
- (2019) Marion Imbert‐Bouteille et al. Molecular Genetics & Genomic Medicine
- MiR-421 promotes the development of osteosarcoma by regulating MCPIP1 expression
- (2019) Zhaozhou Ren et al. CANCER BIOLOGY & THERAPY
- Pazopanib in the Treatment of Bone Sarcomas: Clinical Experience
- (2019) Ninna Aggerholm-Pedersen et al. Translational Oncology
- Biology and pathogenesis of human osteosarcoma (Review)
- (2019) Judson de Azevedo et al. Oncology Letters
- Tumor Syndromes Predisposing to Osteosarcoma
- (2018) Meera Hameed et al. ADVANCES IN ANATOMIC PATHOLOGY
- Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma
- (2018) Yubing Zhou et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma
- (2018) Binghao Li et al. CANCER RESEARCH
- Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment
- (2018) Masanori Kawano et al. Cell Communication and Signaling
- Combined hyperpolarized 13 C-pyruvate MRS and 18 F-FDG PET (hyperPET) estimates of glycolysis in canine cancer patients
- (2018) Adam E. Hansen et al. EUROPEAN JOURNAL OF RADIOLOGY
- Proangiogenic effects of tumor cells on endothelial progenitor cells vary with tumor type in an in vitro and in vivo rat model
- (2018) Ran An et al. FASEB JOURNAL
- The First Approved Gene Therapy Product for Cancer Ad-p53 (Gendicine): 12 Years in the Clinic
- (2018) Wei-Wei Zhang et al. HUMAN GENE THERAPY
- Identifying osteosarcoma metastasis associated genes by weighted gene co-expression network analysis (WGCNA)
- (2018) Honglai Tian et al. MEDICINE
- Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition
- (2018) Laura Pietrovito et al. Molecular Oncology
- Detection of circulating tumor DNA in patients with osteosarcoma
- (2018) David M. Barris et al. Oncotarget
- Cabozantinib Affects Osteosarcoma Growth Through A Direct Effect On Tumor Cells and Modifications In Bone Microenvironment
- (2018) M. Fioramonti et al. Scientific Reports
- Mesenchymal stem cells in the osteosarcoma microenvironment: their biological properties, influence on tumor growth, and therapeutic implications
- (2018) Ying Zheng et al. Stem Cell Research & Therapy
- Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment
- (2018) Franck Verrecchia et al. Frontiers in Oncology
- Pazopanib in relapsed osteosarcoma patients: report on 15 cases
- (2018) Alessandra Longhi et al. ACTA ONCOLOGICA
- OUP accepted manuscript
- (2018) ANNALS OF ONCOLOGY
- MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma
- (2018) Ming Zhuang et al. Cancer Cell International
- Sorafenib in patients with progressed and refractory bone tumors
- (2018) Anna Raciborska et al. MEDICAL ONCOLOGY
- A novel peptide targets CD105 for tumour imaging in�vivo
- (2018) Xiaolong Li et al. ONCOLOGY REPORTS
- Progress in the chemotherapeutic treatment of osteosarcoma (Review)
- (2018) Ya Zhang et al. Oncology Letters
- Genome-Informed Targeted Therapy for Osteosarcoma
- (2018) Leanne C Sayles et al. Cancer Discovery
- Enhancing Osteosacoma Killing and CT Imaging Using Ultrahigh Drug Loading and NIR-Responsive Bismuth Sulfide@Mesoporous Silica Nanoparticles
- (2018) Yao Lu et al. Advanced Healthcare Materials
- Response to Pazopanib in Patients With Relapsed Osteosarcoma
- (2018) Kunal R. Elete et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- miR‑218 suppresses the proliferation of osteosarcoma through downregulation of E2F2
- (2018) Chengmin Xuan et al. Oncology Letters
- The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases
- (2018) Benjamin Navet et al. Cancers
- Soft Tissue Sarcoma Cancer Stem Cells: An Overview
- (2018) Katia C. Genadry et al. Frontiers in Oncology
- Whole transcriptome analysis identifies differentially regulated networks between osteosarcoma and normal bone samples
- (2017) Xuan Dung Ho et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- miRNA profiling identifies deregulated miRNAs associated with osteosarcoma development and time to metastasis in two large cohorts
- (2017) Gitte B. Andersen et al. Molecular Oncology
- Germline and somatic genetics of osteosarcoma — connecting aetiology, biology and therapy
- (2017) D. Matthew Gianferante et al. Nature Reviews Endocrinology
- Evaluation of expression of cancer stem cell markers and fusion gene in synovial sarcoma: Insights into histogenesis and pathogenesis
- (2017) Yang Zhou et al. ONCOLOGY REPORTS
- Pazopanib for second recurrence of osteosarcoma in pediatric patients
- (2017) Katsutsugu Umeda et al. PEDIATRICS INTERNATIONAL
- Exploring targeted therapy of osteosarcoma using proteomics data
- (2017) Parunya Chaiyawat et al. OncoTargets and Therapy
- Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma
- (2017) Sam Behjati et al. Nature Communications
- Biomarkers of Osteosarcoma, Chondrosarcoma, and Ewing Sarcoma
- (2017) Francesco R. Evola et al. Frontiers in Pharmacology
- The contribution of immune infiltrates and the local microenvironment in the pathogenesis of osteosarcoma
- (2017) Marie-Françoise Heymann et al. CELLULAR IMMUNOLOGY
- Whole-exome sequencing in osteosarcoma reveals important heterogeneity of genetic alterations
- (2016) M. Bousquet et al. ANNALS OF ONCOLOGY
- Dichotomous roles of TGF-β in human cancer
- (2016) Jennifer J. Huang et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Molecular mechanisms and microRNAs in osteosarcoma pathogenesis
- (2016) N. E. Kushlinskii et al. BIOCHEMISTRY-MOSCOW
- Advances in osteosarcoma stem cell research and opportunities for novel therapeutic targets
- (2016) Guang-Ning Yan et al. CANCER LETTERS
- Future directions in the treatment of osteosarcoma
- (2016) Michael W. Bishop et al. CURRENT OPINION IN PEDIATRICS
- Fischer-344Tp53-knockout rats exhibit a high rate of bone and brain neoplasia with frequent metastasis
- (2016) Sarah A. Hansen et al. Disease Models & Mechanisms
- Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media From Human Osteosarcoma Cell Lines Reveals Secretion of Proteins Related to Tumor Progression
- (2016) Sofía Jerez et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis
- (2016) Carolina Zandueta et al. JOURNAL OF PATHOLOGY
- Translating microRNAs into biomarkers: What is new for pediatric cancer?
- (2016) Ivna Néria Silva Ribamar de Carvalho et al. MEDICAL ONCOLOGY
- Loss of MicroRNA-489-3p promotes osteosarcoma metastasis by activating PAX3-MET pathway
- (2016) Qifei Liu et al. MOLECULAR CARCINOGENESIS
- miR-421 is a diagnostic and prognostic marker in patients with osteosarcoma
- (2016) Shuguang Zhou et al. TUMOR BIOLOGY
- Cancer stem cells are underestimated by standard experimental methods in clear cell renal cell carcinoma
- (2016) Craig Gedye et al. Scientific Reports
- Somatic TP53 Mutations in the Era of Genome Sequencing
- (2016) Pierre Hainaut et al. Cold Spring Harbor Perspectives in Medicine
- Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells
- (2016) Tomohiro Fujiwara et al. Stem Cells International
- Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies
- (2016) Ander Abarrategi et al. Stem Cells International
- Evolving Role of Molecular Imaging with 18F-Sodium Fluoride PET as a Biomarker for Calcium Metabolism
- (2016) William Raynor et al. Current Osteoporosis Reports
- TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression
- (2016) Audrey Lamora et al. Journal of Clinical Medicine
- Mesenchymal Stem/Stromal Cells under Stress Increase Osteosarcoma Migration and Apoptosis Resistance via Extracellular Vesicle Mediated Communication
- (2016) Krishna C. Vallabhaneni et al. PLoS One
- Health-related quality-of-life results from PALETTE: A randomized, double-blind, phase 3 trial of pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or after prior chemotherapy-a European Organization for res
- (2015) Corneel Coens et al. CANCER
- TP53: an oncogene in disguise
- (2015) T Soussi et al. CELL DEATH AND DIFFERENTIATION
- FBXW7 Acts as an Independent Prognostic Marker and Inhibits Tumor Growth in Human Osteosarcoma
- (2015) Zhanchun Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Germline TP53 Variants and Susceptibility to Osteosarcoma
- (2015) Lisa Mirabello et al. JNCI-Journal of the National Cancer Institute
- Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial
- (2015) Giovanni Grignani et al. LANCET ONCOLOGY
- A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis
- (2015) Branden S Moriarity et al. NATURE GENETICS
- RANKL blockade prevents and treats aggressive osteosarcomas
- (2015) Yan Chen et al. Science Translational Medicine
- MicroRNA-191 promotes osteosarcoma cells proliferation by targeting checkpoint kinase 2
- (2015) Ya-Zeng Huang et al. TUMOR BIOLOGY
- Expression of high mobility group box 1 protein predicts a poorer prognosis for patients with osteosarcoma
- (2015) JILIANG HE et al. Oncology Letters
- Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency
- (2015) Michal Kovac et al. Nature Communications
- TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome
- (2015) Sebastian Ribi et al. Oncotarget
- CCL3 promotes angiogenesis by dysregulation of miR-374b/ VEGF-A axis in human osteosarcoma cells
- (2015) Yuan-Ya Liao et al. Oncotarget
- Increased cathepsin D protein expression is a biomarker for osteosarcomas, pulmonary metastases and other bone malignancies
- (2015) Timo Gemoll et al. Oncotarget
- CXCR4-targeted near-infrared imaging allows detection of orthotopic and metastatic human osteosarcoma in a mouse model
- (2015) Guofeng Guan et al. Scientific Reports
- Germline TP53 Variants and Susceptibility to Osteosarcoma
- (2015) Lisa Mirabello et al. JNCI-Journal of the National Cancer Institute
- Identification of a Plasma Four-microRNA Panel as Potential Noninvasive Biomarker for Osteosarcoma
- (2015) Feng Lian et al. PLoS One
- Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells
- (2015) Gloria Bonuccelli et al. Oncotarget
- Pazopanib in metastatic osteosarcoma: Significant clinical response in three consecutive patients
- (2014) Akmal Safwat et al. ACTA ONCOLOGICA
- Notch Activation as a Driver of Osteogenic Sarcoma
- (2014) Jianning Tao et al. CANCER CELL
- Mechanisms of Acquired Resistance to Tyrosine Kinase Inhibitors in Clear - Cell Renal Cell Carcinoma (ccRCC)
- (2014) Zofia Bielecka et al. Current Signal Transduction Therapy
- Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression
- (2014) Regina Lin et al. JOURNAL OF CLINICAL INVESTIGATION
- Correction: Detection and Characterization of CD133+ Cancer Stem Cells in Human Solid Tumours
- (2014) Virginia Tirino et al. PLoS One
- CD271+ Osteosarcoma Cells Display Stem-Like Properties
- (2014) Jiguang Tian et al. PLoS One
- Prevalence of the TP53 p.R337H Mutation in Breast Cancer Patients in Brazil
- (2014) Juliana Giacomazzi et al. PLoS One
- Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
- (2014) Jennifer A. Perry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Correlations of Ezrin Expression with Pathological Characteristics and Prognosis of Osteosarcoma: A Meta-Analysis
- (2014) Da-Hang Zhao et al. TheScientificWorldJOURNAL
- Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma
- (2014) Xiang Chen et al. Cell Reports
- Resistance to tyrosine kinase inhibitors in clear cell renal cell carcinoma: From the patient's bed to molecular mechanisms
- (2013) Magdalena Buczek et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models
- (2013) Y. Pignochino et al. CLINICAL CANCER RESEARCH
- Osteosarcoma cells promote the production of pro-tumor cytokines in mesenchymal stem cells by inhibiting their osteogenic differentiation through the TGF-β/Smad2/3 pathway
- (2013) Bing Tu et al. EXPERIMENTAL CELL RESEARCH
- Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas
- (2013) Christine G. Joseph et al. GENES CHROMOSOMES & CANCER
- Incidence of neoplasia in Diamond Blackfan anemia: a report from the Diamond Blackfan Anemia Registry
- (2012) A. Vlachos et al. BLOOD
- STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma
- (2012) Bing Tu et al. CANCER LETTERS
- miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma
- (2012) K. B. Jones et al. CANCER RESEARCH
- Mutational Processes Molding the Genomes of 21 Breast Cancers
- (2012) Serena Nik-Zainal et al. CELL
- Creation and preliminary characterization of a Tp53 knockout rat
- (2012) A. McCoy et al. Disease Models & Mechanisms
- Cancer stem cells and their potential implications for the treatment of solid tumors
- (2012) B.A. Grotenhuis et al. JOURNAL OF SURGICAL ONCOLOGY
- c-Myc Overexpression Promotes Osteosarcoma Cell Invasion Via Activation of MEK-ERK Pathway
- (2012) Gang Han et al. ONCOLOGY RESEARCH
- MicroRNA-34a Inhibits the Proliferation and Metastasis of Osteosarcoma Cells Both In Vitro and In Vivo
- (2012) Kang Yan et al. PLoS One
- Transforming Growth Factor β1 Signal is Crucial for Dedifferentiation of Cancer Cells to Cancer Stem Cells in Osteosarcoma
- (2012) Haixia Zhang et al. STEM CELLS
- Li-Fraumeni syndrome: report of a clinical research workshop and creation of a research consortium
- (2012) Phuong L. Mai et al. Cancer Genetics
- Homozygous and Heterozygous p53 Knockout Rats Develop Metastasizing Sarcomas with High Frequency
- (2011) Ruben van Boxtel et al. AMERICAN JOURNAL OF PATHOLOGY
- A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study
- (2011) G. Grignani et al. ANNALS OF ONCOLOGY
- Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
- (2011) Peter Friedl et al. CELL
- Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells
- (2011) G Bulut et al. ONCOGENE
- Concise Review: Mesenchymal Tumors: When Stem Cells Go Mad
- (2011) Alexander B. Mohseny et al. STEM CELLS
- The emerging role of p53 in stem cells
- (2011) Giuseppina Bonizzi et al. TRENDS IN MOLECULAR MEDICINE
- Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma
- (2011) Georges Maire et al. Cancer Genetics
- CD117 and Stro-1 Identify Osteosarcoma Tumor-Initiating Cells Associated with Metastasis and Drug Resistance
- (2010) Amit S. Adhikari et al. CANCER RESEARCH
- Do stem-like cells play a role in drug resistance of sarcomas?
- (2010) Kanya Honoki Expert Review of Anticancer Therapy
- Synovial Sarcoma is a Stem Cell Malignancy
- (2010) Norifumi Naka et al. STEM CELLS
- International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons
- (2009) Lisa Mirabello et al. INTERNATIONAL JOURNAL OF CANCER
- Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice
- (2009) Maya Kansara et al. JOURNAL OF CLINICAL INVESTIGATION
- Beyond Li Fraumeni Syndrome: Clinical Characteristics of Families Withp53Germline Mutations
- (2009) Kelly D. Gonzalez et al. JOURNAL OF CLINICAL ONCOLOGY
- Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways
- (2009) Ymera Pignochino et al. Molecular Cancer
- Mouse Models of p53 Functions
- (2009) G. Lozano Cold Spring Harbor Perspectives in Biology
- The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis
- (2008) Shusheng Wang et al. DEVELOPMENTAL CELL
- The mutation spectrum in RECQL4 diseases
- (2008) H Annika Siitonen et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
- (2008) C. R. Walkley et al. GENES & DEVELOPMENT
- Multiple cutaneous neoplasms in a patient with Rothmund–Thomson syndrome: Case report and published work review
- (2008) Giuseppe STINCO et al. JOURNAL OF DERMATOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now