Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts
Authors
Keywords
-
Journal
Cancers
Volume 12, Issue 7, Pages 1726
Publisher
MDPI AG
Online
2020-06-30
DOI
10.3390/cancers12071726
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Comprehensive transcriptome profiling of Taiwanese colorectal cancer implicates an ethnic basis for pathogenesis
- (2020) Shao-Min Wu et al. Scientific Reports
- Alpelisib: First Global Approval
- (2019) Anthony Markham DRUGS
- Clinical update on head and neck cancer: molecular biology and ongoing challenges
- (2019) Elham Alsahafi et al. Cell Death & Disease
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Multicenter retrospective study of cetuximab plus platinum-based chemotherapy for recurrent or metastatic oral squamous cell carcinoma
- (2018) Souichi Yanamoto et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Survivin-Based Treatment Strategies for Squamous Cell Carcinoma
- (2018) Andrea Santarelli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Phosphatidylinositol 3-Kinase α–Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study
- (2018) Dejan Juric et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting the DNA Damage Response in OSCC with TP53 Mutations
- (2018) A. Lindemann et al. JOURNAL OF DENTAL RESEARCH
- Patient Derived Xenografts (PDX) for personalized treatment of pancreatic cancer: emerging allies in the war on a devastating cancer?
- (2018) Evangelia Sereti et al. Journal of Proteomics
- Targeting the PI3K pathway in cancer: are we making headway?
- (2018) Filip Janku et al. Nature Reviews Clinical Oncology
- Overexpression of PIK3CA in head and neck squamous cell carcinoma is associated with poor outcome and activation of the YAP pathway
- (2018) Ramón García-Escudero et al. ORAL ONCOLOGY
- Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma
- (2018) Xiaobin Bai et al. Translational Oncology
- Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
- (2018) Christina Karamboulas et al. Cell Reports
- Synthetic Lethality Interaction Between Aurora Kinases and CHEK1 Inhibitors in Ovarian Cancer
- (2017) Ana Alcaraz-Sanabria et al. MOLECULAR CANCER THERAPEUTICS
- Prognostic Stratification of Patients With Advanced Oral Cavity Squamous Cell Carcinoma
- (2017) Dante De Paz et al. Current Oncology Reports
- APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism
- (2017) Ting-Wen Chen et al. Nature Communications
- Exome Sequencing of Oral Squamous Cell Carcinoma Reveals Molecular Subgroups and Novel Therapeutic Opportunities
- (2017) Shih-Chi Su et al. Theranostics
- The PI3K/AKT Pathway as a Target for Cancer Treatment
- (2016) Ingrid A. Mayer et al. Annual Review of Medicine
- Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer
- (2016) Justin M. Drake et al. CELL
- Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
- (2015) D. M. Neskey et al. CANCER RESEARCH
- Targeting the DNA Damage Response in Cancer
- (2015) Mark J. O’Connor MOLECULAR CELL
- Ultra-deep targeted sequencing of advanced oral squamous cell carcinoma identifies a mutation-based prognostic gene signature
- (2015) Shu-Jen Chen et al. Oncotarget
- Epidemiology of Oral Cancer in Asia in the Past Decade- An Update (2000-2012)
- (2014) Sree Vidya Krishna Rao et al. Asian Pacific Journal of Cancer Prevention
- Chk1 as a new therapeutic target in triple-negative breast cancer
- (2014) Laurence Albiges et al. BREAST
- Current status of oral cancer treatment strategies: surgical treatments for oral squamous cell carcinoma
- (2014) Ken Omura International Journal of Clinical Oncology
- Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas
- (2013) Rahul A. Parikh et al. GENES CHROMOSOMES & CANCER
- Roles of Chk1 in cell biology and cancer therapy
- (2013) Youwei Zhang et al. INTERNATIONAL JOURNAL OF CANCER
- Chk1/2 Inhibition Overcomes the Cisplatin Resistance of Head and Neck Cancer Cells Secondary to the Loss of Functional p53
- (2013) M. A. Gadhikar et al. MOLECULAR CANCER THERAPEUTICS
- Patient-derived tumour xenografts as models for oncology drug development
- (2012) John J. Tentler et al. Nature Reviews Clinical Oncology
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
- (2012) Guangchuang Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Association of Betel Nut with Carcinogenesis: Revisit with a Clinical Perspective
- (2012) Rajeshwar N. Sharan et al. PLoS One
- PI3K-PKB/Akt Pathway
- (2012) B. A. Hemmings et al. Cold Spring Harbor Perspectives in Biology
- Phosphoproteomic Analysis of Signaling Pathways in Head and Neck Squamous Cell Carcinoma Patient Samples
- (2011) Mitchell J. Frederick et al. AMERICAN JOURNAL OF PATHOLOGY
- RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma
- (2011) K. A. Cole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Head and neck cancer: Response to p53-based therapeutics
- (2010) Jackie Nemunaitis et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Cancer Trends in Taiwan
- (2010) C.-J. Chiang et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Interaction between Tobacco and Alcohol Use and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium
- (2009) M. Hashibe et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Novel inhibitors of the PI3K family
- (2009) Amancio Carnero EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Oral squamous cell carcinoma overview
- (2009) Crispian Scully et al. ORAL ONCOLOGY
- Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1
- (2008) A. Blasina et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of DNA repair throughout the cell cycle
- (2008) Dana Branzei et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started