Expression of inhibitory receptors by B cells in chronic human infectious diseases restricts responses to membrane-associated antigens

IFNγ induces epigenetic programming of human T-bethi B cells and promotesTLR7/8 and IL-21 induced differentiation

(2019) Esther Zumaquero et al.   eLife

The immune cell landscape in kidneys of patients with lupus nephritis

(2019) Arnon Arazi et al.   NATURE IMMUNOLOGY

Epigenetic programming underpins B cell dysfunction in human SLE

(2019) Christopher D. Scharer et al.   NATURE IMMUNOLOGY

B cell signaling in context

(2019) Kihyuck Kwak et al.   NATURE IMMUNOLOGY

The Differentiation in vitro of Human Tonsil B Cells With the Phenotypic and Functional Characteristics of T-bet+ Atypical Memory B Cells in Malaria

(2019) Abhijit A. Ambegaonkar et al.   Frontiers in Immunology

Exhaustion may not be in the human B cell vocabulary, at least not in malaria

(2019) Prasida Holla et al.   IMMUNOLOGICAL REVIEWS

IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

(2018) Shu Wang et al.   Nature Communications

IgG3 regulates tissue-like memory B cells in HIV-infected individuals

(2018) Lela Kardava et al.   NATURE IMMUNOLOGY

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

(2018) Scott A. Jenks et al.   IMMUNITY

High SYK Expression Drives Constitutive Activation of CD21lowB Cells

(2017) Baerbel Keller et al.   JOURNAL OF IMMUNOLOGY

Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells

(2017) Nyamekye Obeng-Adjei et al.   PLoS Pathogens

B cell antigen extraction is regulated by physical properties of antigen-presenting cells

(2016) Katelyn M. Spillane et al.   JOURNAL OF CELL BIOLOGY

Germinal center B cells recognize antigen through a specialized immune synapse architecture

(2016) Carla R Nowosad et al.   NATURE IMMUNOLOGY

Antigen Presentation to B Cells

(2016) Balthasar A. Heesters et al.   TRENDS IN IMMUNOLOGY

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

(2015) Christopher M Tipton et al.   NATURE IMMUNOLOGY

Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8

(2015) Heping Xu et al.   NATURE IMMUNOLOGY

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

(2015) Silvia Portugal et al.   eLife

Malaria Immunity in Man and Mosquito: Insights into Unsolved Mysteries of a Deadly Infectious Disease

(2014) Peter D. Crompton et al.   Annual Review of Immunology

CD19 and CD32b Differentially Regulate Human B Cell Responsiveness

(2014) J. L. Karnell et al.   JOURNAL OF IMMUNOLOGY

Through an ITIM-Independent Mechanism the Fc RIIB Blocks B Cell Activation by Disrupting the Colocalized Microclustering of the B Cell Receptor and CD19

(2014) L. Xu et al.   JOURNAL OF IMMUNOLOGY

An Intensive Longitudinal Cohort Study of Malian Children and Adults Reveals No Evidence of Acquired Immunity to Plasmodium falciparum Infection

(2013) Tuan M. Tran et al.   CLINICAL INFECTIOUS DISEASES

Atypical and classical memory B cells producePlasmodium falciparumneutralizing antibodies

(2013) Matthias F. Muellenbeck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B Cells Use Mechanical Energy to Discriminate Antigen Affinities

(2013) E. Natkanski et al.   SCIENCE

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Polarized Secretion of Lysosomes at the B Cell Synapse Couples Antigen Extraction to Processing and Presentation

(2011) Maria-Isabel Yuseff et al.   IMMUNITY

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

Antigen-Induced Oligomerization of the B Cell Receptor Is an Early Target of FcγRIIB Inhibition

(2010) Wanli Liu et al.   JOURNAL OF IMMUNOLOGY

The Plasmodium falciparum-Specific Human Memory B Cell Compartment Expands Gradually with Repeated Malaria Infections

(2010) Greta E. Weiss et al.   PLoS Pathogens

B cell acquisition of antigen in vivo

(2009) Santiago F Gonzalez et al.   CURRENT OPINION IN IMMUNOLOGY

Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

(2009) Ramon Roozendaal et al.   IMMUNITY

Atypical Memory B Cells Are Greatly Expanded in Individuals Living in a Malaria-Endemic Area

(2009) G. E. Weiss et al.   JOURNAL OF IMMUNOLOGY

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation

(2009) Tri Giang Phan et al.   NATURE IMMUNOLOGY

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunity to malaria: more questions than answers

(2008) Jean Langhorne et al.   NATURE IMMUNOLOGY