Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

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SAP-Regulated T Cell–APC Adhesion and Ligation-Dependent and -Independent Ly108–CD3ζ Interactions

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T–B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction

(2014) Dan Liu et al.   NATURE

Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of IRF4

(2013) Kyoko Ochiai et al.   IMMUNITY

A Role for IRF8 in B Cell Anergy

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Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation

(2013) Bryan Vander Lugt et al.   NATURE IMMUNOLOGY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

B Cell Receptor Signal Transduction in the GC Is Short-Circuited by High Phosphatase Activity

(2012) A. M. Khalil et al.   SCIENCE

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling

(2011) R. Sciammas et al.   Molecular Systems Biology

Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation

(2011) Xinshou Ouyang et al.   Nature Communications

IFN Regulatory Factor 8 Restricts the Size of the Marginal Zone and Follicular B Cell Pools

(2010) J. Feng et al.   JOURNAL OF IMMUNOLOGY

B-cell follicle development remodels the conduit system and allows soluble antigen delivery to follicular dendritic cells

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