Conditional expression of PfAP2-G for controlled massive sexual conversion in Plasmodium falciparum

Dissecting the role of PfAP2-G in malaria gametocytogenesis

(2020) Gabrielle A. Josling et al.   Nature Communications

Identification of antimalarial compounds that require CLAG3 for their uptake by P. falciparum-infected erythrocytes

(2019) Sofía Mira-Martínez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Principles of genome folding into topologically associating domains

(2019) Quentin Szabo et al.   Science Advances

ApiAP2 Transcription Factors in Apicomplexan Parasites

(2019) Myriam Jeninga et al.   Pathogens

Reporter lines based on the gexp02 promoter enable early quantification of sexual conversion rates in the malaria parasite Plasmodium falciparum

(2019) Harvie P. Portugaliza et al.   Scientific Reports

Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation

(2019) Riëtte van Biljon et al.   BMC GENOMICS

Regulation of Sexual Commitment and Gametocytogenesis in Malaria Parasites

(2018) Gabrielle A. Josling et al.   Annual Review of Microbiology

Comparative Heterochromatin Profiling Reveals Conserved and Unique Epigenome Signatures Linked to Adaptation and Development of Malaria Parasites

(2018) Sabine A. Fraschka et al.   Cell Host & Microbe

GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing

(2018) Michael Filarsky et al.   SCIENCE

An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies

(2018) Kathrin Witmer et al.   MALARIA JOURNAL

Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites

(2018) Lisette Meerstein-Kessel et al.   Scientific Reports

Proteomics study of human cord blood reticulocyte-derived exosomes

(2018) Míriam Díaz-Varela et al.   Scientific Reports

Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei

(2018) Robyn S. Kent et al.   Nature Microbiology

Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum

(2018) Cristina Bancells et al.   Nature Microbiology

Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum

(2017) Heather J. Painter et al.   GENOME RESEARCH

Expression of the Plasmodium falciparum Clonally Variant clag3 Genes in Human Infections

(2017) Sofía Mira-Martínez et al.   JOURNAL OF INFECTIOUS DISEASES

Detection of Plasmodium falciparum male and female gametocytes and determination of parasite sex ratio in human endemic populations by novel, cheap and robust RTqPCR assays

(2017) Federica Santolamazza et al.   MALARIA JOURNAL

Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites

(2017) Asaf Poran et al.   NATURE

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission

(2017) David A. Baker et al.   Nature Communications

Generating conditional gene knockouts in Plasmodium – a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9

(2017) Ellen Knuepfer et al.   Scientific Reports

Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae

(2017) Elena Gómez-Díaz et al.   Scientific Reports

malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication

(2017)   PLOS MEDICINE

An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasites

(2017) Daisuke Ito et al.   eLife

The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake

(2017) Emma S Sherling et al.   eLife

Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery

(2016) Sandra Duffy et al.   Nature Protocols

Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions

(2016) Michael J Delves et al.   Nature Protocols

Biology of Malaria Transmission

(2016) Elamaran Meibalan et al.   Cold Spring Harbor Perspectives in Medicine

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage

(2015) Marta Tibúrcio et al.   MALARIA JOURNAL

Deciphering the principles that govern mutually exclusive expression ofPlasmodium falciparum clag3genes

(2015) Núria Rovira-Graells et al.   NUCLEIC ACIDS RESEARCH

The nucleosome landscape ofPlasmodium falciparumreveals chromatin architecture and dynamics of regulatory sequences

(2015) Philip Reiner Kensche et al.   NUCLEIC ACIDS RESEARCH

Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection

(2015) Karell G Pelle et al.   Genome Medicine

Targeting Human Transmission Biology for Malaria Elimination

(2015) Sandra K. Nilsson et al.   PLoS Pathogens

Heterochromatin Protein 1 Secures Survival and Transmission of Malaria Parasites

(2014) Nicolas M.B. Brancucci et al.   Cell Host & Microbe

A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium

(2014) Abhinav Sinha et al.   NATURE

Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

(2014) Qingfeng Zhang et al.   NATURE

A transcriptional switch underlies commitment to sexual development in malaria parasites

(2014) Björn F. C. Kafsack et al.   NATURE

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

(2014) Mehdi Ghorbal et al.   NATURE BIOTECHNOLOGY

Male and Female Plasmodium falciparum Mature Gametocytes Show Different Responses to Antimalarial Drugs

(2013) Michael J. Delves et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Robust inducible Cre recombinase activity in the human malaria parasitePlasmodium falciparumenables efficient gene deletion within a single asexual erythrocytic growth cycle

(2013) Christine R. Collins et al.   MOLECULAR MICROBIOLOGY

Transcriptional variation in the malaria parasite Plasmodium falciparum

(2012) N. Rovira-Graells et al.   GENOME RESEARCH

Plasmodium falciparum Gametocyte Development 1 (Pfgdv1) and Gametocytogenesis Early Gene Identification and Commitment to Sexual Development

(2012) Saliha Eksi et al.   PLoS Pathogens

Malaria Parasite clag3 Genes Determine Channel-Mediated Nutrient Uptake by Infected Red Blood Cells

(2011) Wang Nguitragool et al.   CELL

Protein Export Marks the Early Phase of Gametocytogenesis of the Human Malaria ParasitePlasmodium falciparum

(2010) Francesco Silvestrini et al.   MOLECULAR & CELLULAR PROTEOMICS

Malaria gametocytogenesis

(2010) David A. Baker   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Genome-wide Analysis of Heterochromatin Associates Clonally Variant Gene Regulation with Perinuclear Repressive Centers in Malaria Parasites

(2009) Jose-Juan Lopez-Rubio et al.   Cell Host & Microbe

LISP1 is important for the egress ofPlasmodium bergheiparasites from liver cells

(2009) Tomoko Ishino et al.   CELLULAR MICROBIOLOGY

Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors

(2009) Christian Flueck et al.   PLoS Pathogens