Superparamagnetic Iron Oxide Nanoparticles Carrying Chemotherapeutics Improve Drug Efficacy in Monolayer and Spheroid Cell Culture by Enabling Active Accumulation

Penetration and Uptake of Nanoparticles in 3D Tumor Spheroids

(2019) Aleksandra Tchoryk et al.   BIOCONJUGATE CHEMISTRY

Immunogenic cell death in cancer therapy: Present and emerging inducers

(2019) Jingyi Zhou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nanoparticle Activation Methods in Cancer Treatment

(2019) Benjamin D White et al.   Biomolecules

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Studies on the adsorption and desorption of mitoxantrone to lauric acid/albumin coated iron oxide nanoparticles

(2018) Jan Zaloga et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Pathogenesis and treatment options for chemotherapy-induced alopecia: a systematic review

(2018) Belen Rubio-Gonzalez et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Targeting of drug-loaded nanoparticles to tumor sites increases cell death and release of danger signals

(2018) Magdalena Alev et al.   JOURNAL OF CONTROLLED RELEASE

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning

(2018) Sigrid A. Langhans   Frontiers in Pharmacology

The Chameleon Effect: Characterization Challenges Due to the Variability of Nanoparticles and Their Surfaces

(2018) Donald R. Baer   Frontiers in Chemistry

Nanomedicine: Principles, Properties, and Regulatory Issues

(2018) Sara Soares et al.   Frontiers in Chemistry

Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles

(2018) Parisa Foroozandeh et al.   Nanoscale Research Letters

Biodistribution of single and aggregated gold nanoparticles exposed to the human lung epithelial tissue barrier at the air-liquid interface

(2017) Estelle Durantie et al.   Particle and Fibre Toxicology

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

(2017) George S. Karagiannis et al.   Science Translational Medicine

Cancer Targeted Enzymatic Theranostic Prodrug: Precise Diagnosis and Chemotherapy

(2016) Weon Sup Shin et al.   BIOCONJUGATE CHEMISTRY

Pharmaceutical formulation of HSA hybrid coated iron oxide nanoparticles for magnetic drug targeting

(2016) Jan Zaloga et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Magnetic Drug Targeting: Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans

(2016) Khuloud T. Al-Jamal et al.   NANO LETTERS

CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing

(2016) Andrew J. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Magnetic nanoparticle-based drug delivery for cancer therapy

(2015) Rainer Tietze et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nanoparticle approaches to combating drug resistance

(2015) Jae Hyon Moon et al.   Future Medicinal Chemistry

Different Storage Conditions Influence Biocompatibility and Physicochemical Properties of Iron Oxide Nanoparticles

(2015) Jan Zaloga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Drug Targeting Systems for Cancer Therapy: Nanotechnological Approach

(2015) R. Tigli Aydin   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids

(2015) Annkathrin Hornung et al.   MOLECULES

Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

(2015) YOSHINORI IMAMURA et al.   ONCOLOGY REPORTS

Role of the Tumor Microenvironment in Breast Cancer

(2015) Savas D. Soysal et al.   PATHOBIOLOGY

Spheroid-plug model as a tool to study tumor development, angiogenesis, and heterogeneity in vivo

(2015) Krzysztof Szade et al.   TUMOR BIOLOGY

Quantitative Analysis of the Enhanced Permeation and Retention (EPR) Effect

(2015) Andrew D. Wong et al.   PLoS One

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Development of a lauric acid/albumin hybrid iron oxide nanoparticle system with improved biocompatibility

(2014) Jan Zaloga et al.   International Journal of Nanomedicine

In vitroandin vivoexperiments with iron oxide nanoparticles functionalized with DEXTRAN or polyethylene glycol for medical applications: Magnetic targeting

(2014) M. L. Mojica Pisciotti et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging

(2014) Benjamin Theek et al.   JOURNAL OF CONTROLLED RELEASE

Comparison of active, passive and magnetic targeting to tumors of multifunctional paclitaxel/SPIO-loaded nanoparticles for tumor imaging and therapy

(2014) Nathalie Schleich et al.   JOURNAL OF CONTROLLED RELEASE

Insight into nanoparticle cellular uptake and intracellular targeting

(2014) Basit Yameen et al.   JOURNAL OF CONTROLLED RELEASE

Bench-to-bedside translation of magnetic nanoparticles

(2014) Dhirender Singh et al.   Nanomedicine

Nanoparticles as drug delivery systems

(2014) Agnieszka Z. Wilczewska et al.   Pharmacological Reports

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing

(2013) Paola Longati et al.   BMC CANCER

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

(2013) U. Prabhakar et al.   CANCER RESEARCH

The link between infection and cancer: Tumor vasculature, free radicals, and drug delivery to tumors via the EPR effect

(2013) Hiroshi Maeda   CANCER SCIENCE

Magnetic Drug Targeting Reduces the Chemotherapeutic Burden on Circulating Leukocytes

(2013) Christina Janko et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Efficient drug-delivery using magnetic nanoparticles — biodistribution and therapeutic effects in tumour bearing rabbits

(2013) Rainer Tietze et al.   Nanomedicine-Nanotechnology Biology and Medicine

Impact of the 3D Microenvironment on Phenotype, Gene Expression, and EGFR Inhibition of Colorectal Cancer Cell Lines

(2013) Anna C. Luca et al.   PLoS One

Cell motility and drug gradients in the emergence of resistance to chemotherapy

(2013) A. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Biological applications of magnetic nanoparticles

(2012) Miriam Colombo et al.   CHEMICAL SOCIETY REVIEWS

The Tumor Stroma as Mediator of Drug Resistance - A Potential Target to Improve Cancer Therapy?

(2012) Susanne Sebens et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Effect of Gold Nanoparticle Aggregation on Cell Uptake and Toxicity

(2011) Alexandre Albanese et al.   ACS Nano

Three-Dimensional Collagen I Promotes Gemcitabine Resistance in Pancreatic Cancer through MT1-MMP-Mediated Expression of HMGA2

(2010) S. Dangi-Garimella et al.   CANCER RESEARCH

Paclitaxel Nanocrystals for Overcoming Multidrug Resistance in Cancer

(2010) Yang Liu et al.   MOLECULAR PHARMACEUTICS

Antiangiogenic Targeting Liposomes Increase Therapeutic Efficacy for Solid Tumors

(2009) De-Kuan Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dose Escalation Methods in Phase I Cancer Clinical Trials

(2009) Christophe Le Tourneau et al.   JNCI-Journal of the National Cancer Institute