RECQ1 Helicase in Genomic Stability and Cancer

Identifying breast cancer susceptibility genes – a review of the genetic background in familial breast cancer

(2019) Camilla Wendt et al.   ACTA ONCOLOGICA

Stress Marks on the Genome: Use or Lose?

(2019) Bayan Bokhari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The DNA repair helicase RECQ1 has a checkpoint-dependent role in mediating DNA damage responses induced by gemcitabine

(2019) Swetha Parvathaneni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FANCM and RECQL genetic variants and breast cancer susceptibility: relevance to South Poland and West Ukraine

(2018) Tú Nguyen-Dumont et al.   BMC Medical Genetics

Rare missense mutations in RECQL and POLG associate with inherited predisposition to breast cancer

(2018) Anna Tervasmäki et al.   INTERNATIONAL JOURNAL OF CANCER

Mutations in RECQL are not associated with breast cancer risk in an Australian population

(2018) Na Li et al.   NATURE GENETICS

Familial associations of female breast cancer with other cancers

(2017) Guoqiao Zheng et al.   INTERNATIONAL JOURNAL OF CANCER

RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

(2017) E Viziteu et al.   LEUKEMIA

Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

(2017) Aaron M. Fleming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner

(2017) Swetha Parvathaneni et al.   Oncotarget

RECQ1 Helicase Silencing Decreases the Tumour Growth Rate of U87 Glioblastoma Cell Xenografts in Zebrafish Embryos

(2017) Miloš Vittori et al.   Genes

Germline RECQL mutations in high risk Chinese breast cancer patients

(2016) Ava Kwong et al.   BREAST CANCER RESEARCH AND TREATMENT

Analysis of a RECQL splicing mutation, c.1667_1667+3delAGTA, in breast cancer patients and controls from Central Europe

(2016) Natalia Bogdanova et al.   Familial Cancer

Transcriptome guided identification of novel functions of RECQ1 helicase

(2016) Xing Lu et al.   METHODS

Clinicopathological and Functional Significance of RECQL1 Helicase in Sporadic Breast Cancers

(2016) Arvind Arora et al.   MOLECULAR CANCER THERAPEUTICS

Site-directed mutants of human RECQ1 reveal functional importance of the zinc binding domain

(2016) Furqan Sami et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin

(2015) Furqan Sami et al.   BIOCHEMICAL JOURNAL

Catalytic Strand Separation by RECQ1 Is Required for RPA-Mediated Response to Replication Stress

(2015) Taraswi Banerjee et al.   CURRENT BIOLOGY

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

(2015) X. Li et al.   Molecular Systems Biology

Germline RECQL mutations are associated with breast cancer susceptibility

(2015) Cezary Cybulski et al.   NATURE GENETICS

Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures

(2015) Ashley C. W. Pike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer

(2015) Jie Sun et al.   PLoS Genetics

Human RecQ Helicases in DNA Repair, Recombination, and Replication

(2014) Deborah L. Croteau et al.   Annual Review of Biochemistry

Replication protein A: Single-stranded DNA's first responder

(2014) Ran Chen et al.   BIOESSAYS

Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion

(2014) Xiao Ling Li et al.   CELL CYCLE

RECQL1 Plays an Important Role in the Development of Tongue Squamous Cell Carcinoma

(2014) Jiang Tao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Human RECQL1 participates in telomere maintenance

(2014) Venkateswarlu Popuri et al.   NUCLEIC ACIDS RESEARCH

An appraisal of RECQ1 expression in cancer progression

(2014) Sudha Sharma   Frontiers in Genetics

Flap Endonuclease 1

(2013) Lata Balakrishnan et al.   Annual Review of Biochemistry

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D

(2013) Xing Lu et al.   Molecular Cancer

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

(2013) Matteo Berti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks

(2013) Swetha Parvathaneni et al.   PLoS One

RECQL1 DNA Repair Helicase: A Potential Therapeutic Target and a Proliferative Marker against Ovarian Cancer

(2013) Sakiko Sanada et al.   PLoS One

PROBING GENOME MAINTENANCE FUNCTIONS OF HUMAN RECQ1

(2013) Furqan Sami et al.   Computational and Structural Biotechnology Journal

RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures

(2012) Venkateswarlu Popuri et al.   CELL CYCLE

RECQ1 plays a distinct role in cellular response to oxidative DNA damage

(2012) Sudha Sharma et al.   DNA REPAIR

Transcription directed by human core promoters with a HomolD box sequence requires DDB1, RECQL and RNA polymerase II machinery

(2012) Juan Contreras-Levicoy et al.   GENE

RECQL1 and WRN Proteins Are Potential Therapeutic Targets in Head and Neck Squamous Cell Carcinoma

(2011) A. Arai et al.   CANCER RESEARCH

The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses

(2011) Ramachander V.N. Turaga et al.   CELL CYCLE

PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro

(2011) Yiyong Liu et al.   DNA REPAIR

The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation

(2011) Ramiro Mendoza-Maldonado et al.   Molecular Cancer

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Probing the structural basis of RecQ helicase function

(2010) Alessandro Vindigni et al.   BIOPHYSICAL CHEMISTRY

RecQL1 DNA repair helicase: A potential tumor marker and therapeutic target against hepatocellular carcinoma

(2010) Furuichi   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Mutational Heterogeneity in Human Cancers: Origin and Consequences

(2009) Jesse J. Salk et al.   Annual Review of Pathology-Mechanisms of Disease

Direct Inhibition of RNA Polymerase II Transcription by RECQL5

(2009) Ozan Aygün et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

(2009) Jay E. Johnson et al.   NUCLEIC ACIDS RESEARCH

Barrier-to-Autointegration Factor Proteome Reveals Chromatin-Regulatory Partners

(2009) Rocío Montes de Oca et al.   PLoS One

Structure of the human RECQ1 helicase reveals a putative strand-separation pin

(2009) A. C. W. Pike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models

(2008) Kazunobu Futami et al.   CANCER SCIENCE

Flap Endonuclease 1 Contributes to Telomere Stability

(2008) Abhishek Saharia et al.   CURRENT BIOLOGY

The Human RecQ Helicases, BLM and RECQ1, Display Distinct DNA Substrate Specificities

(2008) Venkateswarlu Popuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processing of DNA Replication and Repair Intermediates by the Concerted Action of RecQ Helicases and Rad2 Structure-Specific Nucleases

(2008) Robert Brosh et al.   PROTEIN AND PEPTIDE LETTERS