Human RECQL1 participates in telomere maintenance

DNA binding residues in the RQC domain of Werner protein are critical for its catalytic activities

(2016) Takashi Tadokoro et al.   Aging-US

The RECQL4 protein, deficient in Rothmund–Thomson syndrome is active on telomeric D-loops containing DNA metabolism blocking lesions

(2013) Leslie K. Ferrarelli et al.   DNA REPAIR

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D

(2013) Xing Lu et al.   Molecular Cancer

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

(2013) Matteo Berti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures

(2012) Venkateswarlu Popuri et al.   CELL CYCLE

RECQ1 plays a distinct role in cellular response to oxidative DNA damage

(2012) Sudha Sharma et al.   DNA REPAIR

53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response

(2012) Paula Martínez et al.   JOURNAL OF CELL BIOLOGY

The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

(2012) Aaron Mendez-Bermudez et al.   NUCLEIC ACIDS RESEARCH

RECQL5 plays co-operative and complementary roles with WRN syndrome helicase

(2012) Venkateswarlu Popuri et al.   NUCLEIC ACIDS RESEARCH

The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures

(2012) Colleen Barefield et al.   NUCLEIC ACIDS RESEARCH

RECQL1 and WRN Proteins Are Potential Therapeutic Targets in Head and Neck Squamous Cell Carcinoma

(2011) A. Arai et al.   CANCER RESEARCH

RECQL4, the Protein Mutated in Rothmund-Thomson Syndrome, Functions in Telomere Maintenance

(2011) Avik K. Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation

(2011) Ramiro Mendoza-Maldonado et al.   Molecular Cancer

Telomere Protection by TPP1/POT1 Requires Tethering to TIN2

(2011) Kaori K. Takai et al.   MOLECULAR CELL

RecQ helicases in DNA double strand break repair and telomere maintenance

(2011) Dharmendra Kumar Singh et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation

(2010) S. Thangavel et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase

(2010) Gerald J. Nora et al.   NUCLEIC ACIDS RESEARCH

Purification of Proteins Associated with Specific Genomic Loci

(2009) Jérôme Déjardin et al.   CELL

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

Telomeres and disease

(2009) Peter M Lansdorp   EMBO JOURNAL

Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN

(2009) N. Arnoult et al.   GENES & DEVELOPMENT

Telomeric D-loops Containing 8-Oxo-2′-deoxyguanosine Are Preferred Substrates for Werner and Bloom Syndrome Helicases and Are Bound by POT1

(2009) Avik Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Werner Syndrome Helicase/Exonuclease Processes Mobile D-Loops through Branch Migration and Degradation

(2009) Patricia L. Opresko et al.   PLoS One

Structure of the human RECQ1 helicase reveals a putative strand-separation pin

(2009) A. C. W. Pike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short Telomeres Initiate Telomere Recombination in Primary and Tumor Cells

(2009) Tammy A. Morrish et al.   PLoS Genetics

Telomere elongation involves intra-molecular DNA replication in cells utilizing alternative lengthening of telomeres

(2008) A. Muntoni et al.   HUMAN MOLECULAR GENETICS

The Human RecQ Helicases, BLM and RECQ1, Display Distinct DNA Substrate Specificities

(2008) Venkateswarlu Popuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomere uncapping and alternative lengthening of telomeres

(2007) Anthony J. Cesare et al.   MECHANISMS OF AGEING AND DEVELOPMENT