A Human 2D Primary Organoid-Derived Epithelial Monolayer Model to Study Host-Pathogen Interaction in the Small Intestine

Crossing the Intestinal Barrier via Listeria Adhesion Protein and Internalin A

(2019) Rishi Drolia et al.   TRENDS IN MICROBIOLOGY

Type III interferon signaling restricts enterovirus 71 infection of goblet cells

(2019) Charles Good et al.   Science Advances

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium

(2019) Julie G. In et al.   Jove-Journal of Visualized Experiments

Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation

(2018) Rishi Drolia et al.   Cell Host & Microbe

Comparison of listeriolysin O and phospholipases PlcA and PlcB activities, and initial intracellular growth capability among food and clinical strains of Listeria monocytogenes

(2018) M. Kanki et al.   JOURNAL OF APPLIED MICROBIOLOGY

Translocation of a gut pathobiont drives autoimmunity in mice and humans

(2018) S. Manfredo Vieira et al.   SCIENCE

Optimized procedures for generating an enhanced, near physiological 2D culture system from porcine intestinal organoids

(2018) B. van der Hee et al.   Stem Cell Research

The Intestinal Epithelium: Central Coordinator of Mucosal Immunity

(2018) Joannie M. Allaire et al.   TRENDS IN IMMUNOLOGY

Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids

(2018) Anubama Rajan et al.   mBio

A urine-dependent human urothelial organoid offers a potential alternative to rodent models of infection

(2018) Harry Horsley et al.   Scientific Reports

Organoid and Enteroid Modeling of Salmonella Infection

(2018) Yuebang Yin et al.   Frontiers in Cellular and Infection Microbiology

Outgrowing the Immaturity Myth: The Cost of Defending From Neonatal Infectious Disease

(2018) Danny Harbeson et al.   Frontiers in Immunology

Generation of renewable mouse intestinal epithelial cell monolayers and organoids for functional analyses

(2018) Emily C. Moorefield et al.   BMC CELL BIOLOGY

Development of a host–microbiome model of the small intestine

(2018) Marta Calatayud et al.   FASEB JOURNAL

Recent progress in organoid culture to model intestinal epithelial barrier functions

(2018) Tetsuya Nakamura   INTERNATIONAL IMMUNOLOGY

Gut microbiota and IBD: causation or correlation?

(2017) Josephine Ni et al.   Nature Reviews Gastroenterology & Hepatology

Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis

(2017) Lilliana Radoshevich et al.   NATURE REVIEWS MICROBIOLOGY

1-alpha,25-Dihydroxyvitamin D 3 up-regulates the expression of 2 types of human intestinal alkaline phosphatase alternative splicing variants in Caco-2 cells and may be an important regulator of their expression in gut homeostasis

(2017) Seiko Noda et al.   NUTRITION RESEARCH

Morphogenesis and maturation of the embryonic and postnatal intestine

(2017) Alana M. Chin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Erratum: A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions

(2017) Gaelle Noel et al.   Scientific Reports

Replication of CMV in the gut of HIV-infected individuals and epithelial barrier dysfunction

(2017) Ekaterina Maidji et al.   PLoS Pathogens

Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer Platform

(2017) Kenji Kozuka et al.   Stem Cell Reports

Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli

(2017) Sayali S. Karve et al.   PLoS One

In vitropatterning of pluripotent stem cell-derived intestine recapitulatesin vivohuman development

(2016) Yu-Hwai Tsai et al.   DEVELOPMENT

Physiologically relevant human tissue models for infectious diseases

(2016) Melody Mills et al.   DRUG DISCOVERY TODAY

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Human mini-guts: new insights into intestinal physiology and host–pathogen interactions

(2016) Julie G. In et al.   Nature Reviews Gastroenterology & Hepatology

Plasticity of the brush border — the yin and yang of intestinal homeostasis

(2016) Delphine Delacour et al.   Nature Reviews Gastroenterology & Hepatology

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

(2015) Kapil Saxena et al.   JOURNAL OF VIROLOGY

Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation

(2015) Andreas Kühbacher et al.   mBio

Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays

(2014) Kelli L VanDussen et al.   GUT

Shaping the intestinal brush border

(2014) Scott W. Crawley et al.   JOURNAL OF CELL BIOLOGY

Ontogeny of Intestinal Epithelial Innate Immune Responses

(2014) Mathias W. Hornef et al.   Frontiers in Immunology

Neonatal Immune Adaptation of the Gut and Its Role during Infections

(2013) Emilie Tourneur et al.   Clinical & Developmental Immunology

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis

(2013) C Moon et al.   Mucosal Immunology

Secreted Listeria adhesion protein (Lap) influences Lap-mediated Listeria monocytogenes paracellular translocation through epithelial barrier

(2013) Hyochin Kim et al.   Gut Pathogens

Transcytosis ofListeria monocytogenesacross the intestinal barrier upon specific targeting of goblet cell accessible E-cadherin

(2011) Georgios Nikitas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

New Concepts of Microbial Translocation in the Neonatal Intestine: Mechanisms and Prevention

(2010) Michael P. Sherman   CLINICS IN PERINATOLOGY

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data

(2009) J. M. Ruijter et al.   NUCLEIC ACIDS RESEARCH

Listeria monocytogenes internalins bind to the human intestinal mucin MUC2

(2008) Sara K. Lindén et al.   ARCHIVES OF MICROBIOLOGY

The Caco-2 cell monolayer: usefulness and limitations

(2008) Huadong Sun et al.   Expert Opinion on Drug Metabolism & Toxicology