Organoid and Enteroid Modeling of Salmonella Infection

Epithelial organoid cultures from patients with ulcerative colitis and Crohn's disease: a truly long-term model to study the molecular basis for inflammatory bowel disease?

(2017) Manuel Noben et al.   GUT

Organoids as preclinical models to improve intraperitoneal chemotherapy effectiveness for colorectal cancer patients with peritoneal metastases: Preclinical models to improve HIPEC

(2017) P. Roy et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

(2017) Shu Zhu et al.   NATURE

Disease Modeling in Stem Cell-Derived 3D Organoid Systems

(2017) Devanjali Dutta et al.   TRENDS IN MOLECULAR MEDICINE

Alpha-defensin-dependent enhancement of enteric viral infection

(2017) Sarah S. Wilson et al.   PLoS Pathogens

speG Is Required for Intracellular Replication of Salmonella in Various Human Cells and Affects Its Polyamine Metabolism and Global Transcriptomes

(2017) Shiuh-Bin Fang et al.   Frontiers in Microbiology

Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli

(2017) Sayali S. Karve et al.   PLoS One

Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella

(2016) Fabian Rivera-Chávez et al.   Cell Host & Microbe

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

Replication of human noroviruses in stem cell-derived human enteroids

(2016) K. Ettayebi et al.   SCIENCE

Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients with Intestinal Failure

(2016) Sung Noh Hong et al.   Stem Cells Translational Medicine

The Pyromaniac Inside You:SalmonellaMetabolism in the Host Gut

(2015) Fabian Rivera-Chávez et al.   Annual Review of Microbiology

Modeling rotavirus infection and antiviral therapy using primary intestinal organoids

(2015) Yuebang Yin et al.   ANTIVIRAL RESEARCH

Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma

(2015) Tiziana Scanu et al.   Cell Host & Microbe

Epidemiology, Clinical Presentation, Laboratory Diagnosis, Antimicrobial Resistance, and Antimicrobial Management of Invasive Salmonella Infections

(2015) John A. Crump et al.   CLINICAL MICROBIOLOGY REVIEWS

In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

(2015) Sina Bartfeld et al.   GASTROENTEROLOGY

Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells

(2015) Jessica L. Forbester et al.   INFECTION AND IMMUNITY

The Periplasmic Nitrate Reductase NapABC Supports Luminal Growth of Salmonella enterica Serovar Typhimurium during Colitis

(2015) Christopher A. Lopez et al.   INFECTION AND IMMUNITY

Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

(2015) Nicholas C. Zachos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Milk Oligosaccharides and Synthetic Galactosyloligosaccharides Contain 3′-, 4-, and 6′-Galactosyllactose and Attenuate Inflammation in Human T84, NCM-460, and H4 Cells and Intestinal Tissue Ex Vivo

(2015) David S Newburg et al.   JOURNAL OF NUTRITION

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

(2015) Kapil Saxena et al.   JOURNAL OF VIROLOGY

Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids

(2015) Mami Matano et al.   NATURE MEDICINE

Salmonella: A review on pathogenesis, epidemiology and antibiotic resistance

(2015) Shu-Kee Eng et al.   Frontiers in Life Science

A Protocol for Lentiviral Transduction and Downstream Analysis of Intestinal Organoids

(2015) Jooske F. Van Lidth de Jeude et al.   Jove-Journal of Visualized Experiments

Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract

(2014) Jennifer Foulke-Abel et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Persistence and Toxin Production by Clostridium difficile within Human Intestinal Organoids Result in Disruption of Epithelial Paracellular Barrier Function

(2014) Jhansi L. Leslie et al.   INFECTION AND IMMUNITY

A small intestinal organoid model of non-invasive enteric pathogen–epithelial cell interactions

(2014) S S Wilson et al.   Mucosal Immunology

Age-Dependent Enterocyte Invasion and Microcolony Formation by Salmonella

(2014) Kaiyi Zhang et al.   PLoS Pathogens

Salmonella–Host Interactions – Modulation of the Host Innate Immune System

(2014) Daniel Hurley et al.   Frontiers in Immunology

A functional CFTR assay using primary cystic fibrosis intestinal organoids

(2013) Johanna F Dekkers et al.   NATURE MEDICINE

Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny

(2013) Xiaolei Yin et al.   NATURE METHODS

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture

(2013) Hiroyuki Miyoshi et al.   Nature Protocols

Challenges of Culturing Human Norovirus in Three-Dimensional Organoid Intestinal Cell Culture Models

(2013) Efstathia Papafragkou et al.   PLoS One

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Salmonella Uses Energy Taxis to Benefit from Intestinal Inflammation

(2013) Fabian Rivera-Chávez et al.   PLoS Pathogens

A nomenclature for intestinal in vitro cultures

(2012) Matthias Stelzner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Use of Carbapenems against Clinical, Nontyphoid Salmonella Isolates: Results fromIn VitroandIn VivoAnimal Studies

(2012) Hung-Jen Tang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

(2012) Katerina Tsilingiri et al.   GUT

Use of Urine with Nested PCR Targeting the Flagellin Gene (fliC) for Diagnosis of Typhoid Fever

(2012) Gopal Kumar et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured "Miniguts"

(2012) W. de Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Very Long O-antigen Chains Enhance Fitness during Salmonella-induced Colitis by Increasing Bile Resistance

(2012) Robert W. Crawford et al.   PLoS Pathogens

Humanized mice are susceptible to Salmonella typhi infection

(2011) M Firoz Mian et al.   Cellular & Molecular Immunology

Molecular and Cellular Characterization of a Salmonella enterica Serovar Paratyphi A Outbreak Strain and the Human Immune Response to Infection

(2011) Ohad Gal-Mor et al.   Clinical and Vaccine Immunology

Invasive nontyphoidal Salmonella disease

(2011) Melita A. Gordon   CURRENT OPINION IN INFECTIOUS DISEASES

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Epithelial Cell Coculture Models for Studying Infectious Diseases: Benefits and Limitations

(2011) Benjamin L. Duell et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Development of protective immunity to Salmonella, a mucosal pathogen with a systemic agenda

(2011) A J Griffin et al.   Mucosal Immunology

Humanized Mice for Modeling Human Infectious Disease: Challenges, Progress, and Outlook

(2009) Nicolas Legrand et al.   Cell Host & Microbe

Effect of age on susceptibility to Salmonella Typhimurium infection in C57BL/6 mice

(2009) Z. Ren et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

New in vitro colonic fermentation model for Salmonella infection in the child gut

(2008) Gwenaëlle Le Blay et al.   FEMS MICROBIOLOGY ECOLOGY

Salmonella translocates across an in vitro M cell model independently of SPI-1 and SPI-2

(2008) I. Martinez-Argudo et al.   MICROBIOLOGY-SGM