In vitropatterning of pluripotent stem cell-derived intestine recapitulatesin vivohuman development

Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile

(2015) Melinda A. Engevik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Human Clostridium difficile infection: altered mucus production and composition

(2015) Melinda A. Engevik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal organoids: A model of intestinal fibrosis for evaluating anti-fibrotic drugs

(2015) Eva S. Rodansky et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Cloning and variation of ground state intestinal stem cells

(2015) Xia Wang et al.   NATURE

In vitro generation of human pluripotent stem cell derived lung organoids

(2015) Briana R Dye et al.   eLife

Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids

(2015) S. R. Finkbeiner et al.   Biology Open

Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo

(2015) Stacy R. Finkbeiner et al.   Stem Cell Reports

Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1

(2015) Kaisa Tamminen et al.   PLoS One

Persistence and Toxin Production by Clostridium difficile within Human Intestinal Organoids Result in Disruption of Epithelial Paracellular Barrier Function

(2014) Jhansi L. Leslie et al.   INFECTION AND IMMUNITY

An in vivo model of human small intestine using pluripotent stem cells

(2014) Carey L Watson et al.   NATURE MEDICINE

Adult Stem Cells in the Small Intestine Are Intrinsically Programmed with Their Location-Specific Function

(2014) Sabine Middendorp et al.   STEM CELLS

De Novo Formation of Insulin-Producing “Neo-β Cell Islets” from Intestinal Crypts

(2014) Yi-Ju Chen et al.   Cell Reports

Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice

(2013) Xiang Xue et al.   GASTROENTEROLOGY

Human tissue-engineered small intestine forms from postnatal progenitor cells

(2013) Daniel E. Levin et al.   JOURNAL OF PEDIATRIC SURGERY

Development of intestinal organoids as tissue surrogates: Cell composition and the Epigenetic control of differentiation

(2013) Li Cao et al.   MOLECULAR CARCINOGENESIS

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

(2013) B. E. Rockich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

(2013) Jarom Heijmans et al.   Cell Reports

Generation of Multipotent Foregut Stem Cells from Human Pluripotent Stem Cells

(2013) Nicholas R.F. Hannan et al.   Stem Cell Reports

Identification of a cKit+ Colonic Crypt Base Secretory Cell That Supports Lgr5+ Stem Cells in Mice

(2012) Michael E. Rothenberg et al.   GASTROENTEROLOGY

Intestinal Master Transcription Factor CDX2 Controls Chromatin Access for Partner Transcription Factor Binding

(2012) M. P. Verzi et al.   MOLECULAR AND CELLULAR BIOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Stem Cell-Derived Human Intestinal Organoids as an Infection Model for Rotaviruses

(2012) S. R. Finkbeiner et al.   mBio

Wnt signaling specifies and patterns intestinal endoderm

(2011) Richard I. Sherwood et al.   MECHANISMS OF DEVELOPMENT

Generating human intestinal tissue from pluripotent stem cells in vitro

(2011) Kyle W McCracken et al.   Nature Protocols

Absence of Gastrointestinal Pathogens in Ileum Tissue Resected for Necrotizing Enterocolitis

(2011) Tim Ullrich et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Generating intestinal tissue from stem cells: potential for research and therapy

(2011) Jonathan C Howell et al.   Regenerative Medicine

Cdx2 regulates patterning of the intestinal epithelium

(2010) Stephanie Grainger et al.   DEVELOPMENTAL BIOLOGY

Differentiation-Specific Histone Modifications Reveal Dynamic Chromatin Interactions and Partners for the Intestinal Transcription Factor CDX2

(2010) Michael P. Verzi et al.   DEVELOPMENTAL CELL

Intestinal lineage commitment of embryonic stem cells

(2010) Li Cao et al.   DIFFERENTIATION

Cdx2 regulates endo-lysosomal function and epithelial cell polarity

(2010) N. Gao et al.   GENES & DEVELOPMENT

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

(2010) Jason R. Spence et al.   NATURE

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Establishment of Intestinal Identity and Epithelial-Mesenchymal Signaling by Cdx2

(2009) Nan Gao et al.   DEVELOPMENTAL CELL

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo

(2009) Sebastian J. Arnold et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis

(2008) S. M. Bell et al.   DEVELOPMENT

Transcriptional dynamics of endodermal organ formation

(2008) Richard I. Sherwood et al.   DEVELOPMENTAL DYNAMICS

GATA4 Is Essential for Jejunal Function in Mice

(2008) Michele A. Battle et al.   GASTROENTEROLOGY