Management of epigenomic networks entailed in coronavirus infections and COVID-19

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

(2020) Chih-Cheng Lai et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?

(2020) Noah C Peeri et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak

(2020) Hussin A. Rothan et al.   JOURNAL OF AUTOIMMUNITY

Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4

(2020) David Diaz-Jimenez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARSCoV-2): Facts and myths

(2020) Chih-Cheng Lai et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

(2020) Guangdi Li et al.   NATURE REVIEWS DRUG DISCOVERY

Coronavirus (COVID-19) Outbreak: What the Department of Radiology Should Know

(2020) Soheil Kooraki et al.   Journal of the American College of Radiology

Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs

(2020) Amina Ait-Ammar et al.   Frontiers in Microbiology

The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China

(2020) Wen Zhang et al.   CLINICAL IMMUNOLOGY

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19

(2020) Hao Cheng et al.   JOURNAL OF MEDICAL VIROLOGY

ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome

(2020) Christian A. Devaux et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Chloroquine or hydroxychloroquine for prophylaxis of COVID-19

(2020) Nicola Principi et al.   LANCET INFECTIOUS DISEASES

Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review

(2020) Sasmita Poudel Adhikari et al.   Infectious Diseases of Poverty

Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development

(2020) Eun Kim et al.   EBioMedicine

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

(2020) Yadi Zhou et al.   Cell Discovery

Molecular immune pathogenesis and diagnosis of COVID-19

(2020) Xiaowei Li et al.   Journal of Pharmaceutical Analysis

Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients

(2020) Amr H. Sawalha et al.   CLINICAL IMMUNOLOGY

ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19

(2020) Bruna G G Pinto et al.   JOURNAL OF INFECTIOUS DISEASES

SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccines

(2020) Giovanni Salvatori et al.   Journal of Translational Medicine

Coronavirus breakthrough: dexamethasone is first drug shown to save lives

(2020) Heidi Ledford   NATURE

COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses

(2020) Muhammad Adnan Shereen et al.   Journal of Advanced Research

Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus

(2020) Calvin A. Omolo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Control of viral infections by epigenetic-targeted therapy

(2019) Zeina Nehme et al.   Clinical Epigenetics

Epigenetic regulation of macrophages: from homeostasis maintenance to host defense

(2019) Siyuan Chen et al.   Cellular & Molecular Immunology

Epigenetic and transcriptional mechanisms for the regulation of IL-10

(2019) Huiyuan Zhang et al.   SEMINARS IN IMMUNOLOGY

The protective effect of resveratrol on vascular aging by modulation of the renin–angiotensin system

(2018) Eun Nim Kim et al.   ATHEROSCLEROSIS

Potent and Selective Inhibitors of Human Sirtuin 5

(2018) Diana Kalbas et al.   JOURNAL OF MEDICINAL CHEMISTRY

MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape

(2018) Vineet D. Menachery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney

(2018) In-Ae Jang et al.   Nutrients

Inhibition of NF-κB Signaling Pathway by Resveratrol Improves Spinal Cord Injury

(2018) Luyao Xu et al.   Frontiers in Neuroscience

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction

(2017) Juan Li et al.   Oncotarget

The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells

(2017) Michael Poppe et al.   PLoS Pathogens

Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patients

(2017) Fei Yang et al.   Scientific Reports

P-TEFb goes viral

(2016) Justyna Zaborowska et al.   BIOESSAYS

The therapeutic potential of epigenetic manipulation during infectious diseases

(2016) Joby Cole et al.   PHARMACOLOGY & THERAPEUTICS

The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

(2015) Yahira M. Báez-Santos et al.   ANTIVIRAL RESEARCH

Beyond receptors and signaling: epigenetic factors in the regulation of innate immunity

(2015) Stuti Mehta et al.   IMMUNOLOGY AND CELL BIOLOGY

Intricate Roles of Mammalian Sirtuins in Defense against Viral Pathogens

(2015) Hanna G. Budayeva et al.   JOURNAL OF VIROLOGY

Epigenetic Regulation of Inflammatory Cytokines and Associated Genes in Human Malignancies

(2015) Rehana Yasmin et al.   MEDIATORS OF INFLAMMATION

Resveratrol, sirtuins, and viruses

(2015) Tao Yang et al.   REVIEWS IN MEDICAL VIROLOGY

The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells

(2015) Y-S Lai et al.   Blood Cancer Journal

The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway

(2015) Emma M. Smith et al.   Oncotarget

Animal Model of Respiratory Syncytial Virus: CD8+ T Cells Cause a Cytokine Storm That Is Chemically Tractable by Sphingosine-1-Phosphate 1 Receptor Agonist Therapy

(2014) K. B. Walsh et al.   JOURNAL OF VIROLOGY

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

(2014) Lorenzo Subissi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of SIRT1 in Diabetic Kidney Disease

(2014) Rabi Yacoub et al.   Frontiers in Endocrinology

Epigenetic regulation of angiotensin-converting enzyme 2 (ACE2) by SIRT1 under conditions of cell energy stress

(2013) Nicola E. Clarke et al.   CLINICAL SCIENCE

Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases

(2013) Frank J. Dekker et al.   DRUG DISCOVERY TODAY

The viral RNA capping machinery as a target for antiviral drugs

(2012) François Ferron et al.   ANTIVIRAL RESEARCH

Promoter methylation of aminopeptidase N/CD13 in malignant melanoma

(2012) Jens Wulfänger et al.   CARCINOGENESIS

Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression

(2012) Lena Larsson et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Differences in neutralizing antigenicity between laboratory and clinical isolates of HCoV-229E isolated in Japan in 2004-2008 depend on the S1 region sequence of the spike protein

(2012) K. Shirato et al.   JOURNAL OF GENERAL VIROLOGY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic regulation of immune cell functions during post-septic immunosuppression

(2011) William F. Carson et al.   Epigenetics

Histone deacetylases in viral infections

(2010) Georges Herbein et al.   Clinical Epigenetics

Chromatin-modifying enzymes as therapeutic targets – Part 1

(2008) Brian R Keppler et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells

(2008) Marielle Dejligbjerg et al.   Molecular Cancer