The protean prion protein

Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core

(2020) Calina Glynn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

(2020) Emmanuel A. Asante et al.   PLOS BIOLOGY

The Prion 2018 round tables (I): The structure of PrPSc

(2019) Ilia V. Baskakov et al.   Prion

Full atomistic model of prion structure and conversion

(2019) Giovanni Spagnolli et al.   PLoS Pathogens

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions

(2016) Rona M. Barron et al.   ACTA NEUROPATHOLOGICA

Amyloid fibrils from the N-terminal prion protein fragment are infectious

(2016) Jin-Kyu Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parallel In-register Intermolecular β-Sheet Architectures for Prion-seeded Prion Protein (PrP) Amyloids

(2014) Bradley R. Groveman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked

(2014) Malin K. Sandberg et al.   Nature Communications

Probing the N-Terminal β-Sheet Conversion in the Crystal Structure of the Human Prion Protein Bound to a Nanobody

(2013) Romany N. N. Abskharon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small Ruminant Nor98 Prions Share Biochemical Features with Human Gerstmann-Sträussler-Scheinker Disease and Variably Protease-Sensitive Prionopathy

(2013) Laura Pirisinu et al.   PLoS One

Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein

(2013) Emmanuel A. Asante et al.   PLoS Pathogens

Genesis of tramsmissible protein states via deformed templating

(2012) Natallia Makarava et al.   Prion

The α-Helical C-Terminal Domain of Full-Length Recombinant PrP Converts to an In-Register Parallel β-Sheet Structure in PrP Fibrils: Evidence from Solid State Nuclear Magnetic Resonance

(2010) Robert Tycko et al.   BIOCHEMISTRY