Parallel In-register Intermolecular β-Sheet Architectures for Prion-seeded Prion Protein (PrP) Amyloids

Prions and the Potential Transmissibility of Protein Misfolding Diseases

(2013) Allison Kraus et al.   Annual Review of Microbiology

Amyloids and Yeast Prion Biology

(2013) Reed B. Wickner et al.   BIOCHEMISTRY

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Structural Organization of Mammalian Prions as Probed by Limited Proteolysis

(2012) Ester Vázquez-Fernández et al.   PLoS One

Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions

(2012) N. R. Deleault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid Structure: Conformational Diversity and Consequences

(2011) Brandon H. Toyama et al.   Annual Review of Biochemistry

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Effect of Glycans and the Glycophosphatidylinositol Anchor on Strain Dependent Conformations of Scrapie Prion Protein: Improved Purifications and Infrared Spectra

(2011) Gerald S. Baron et al.   BIOCHEMISTRY

Seeding Specificity and Ultrastructural Characteristics of Infectious Recombinant Prions

(2011) Justin R. Piro et al.   BIOCHEMISTRY

Structural Polymorphism in Amyloids

(2011) Eric M. Jones et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Globular Domain of the Prion Protein Needs to Be Unlocked by Domain Swapping to Support Prion Protein Conversion

(2011) Iva Hafner-Bratkovič et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intermolecular Alignment in Y145Stop Human Prion Protein Amyloid Fibrils Probed by Solid-State NMR Spectroscopy

(2011) Jonathan J. Helmus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange

(2011) Vytautas Smirnovas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Prion Disease Blood Test Using Immunoprecipitation and Improved Quaking-Induced Conversion

(2011) C. D. Orru et al.   mBio

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

(2010) Natallia Makarava et al.   ACTA NEUROPATHOLOGICA

The α-Helical C-Terminal Domain of Full-Length Recombinant PrP Converts to an In-Register Parallel β-Sheet Structure in PrP Fibrils: Evidence from Solid State Nuclear Magnetic Resonance

(2010) Robert Tycko et al.   BIOCHEMISTRY

2Struc: the secondary structure server

(2010) D. P. Klose et al.   BIOINFORMATICS

Prion amyloid structure explains templating: how proteins can be genes

(2010) Reed B. Wickner et al.   FEMS YEAST RESEARCH

Prion Fibrillization Is Mediated by a Native Structural Element That Comprises Helices H2 and H3

(2010) Miquel Adrover et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

(2010) Jae-Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays

(2010) Jason M. Wilham et al.   PLoS Pathogens

Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions

(2009) Byron Caughey et al.   Annual Review of Biochemistry

Distinct Structures of Scrapie Prion Protein (PrPSc)-seededVersusSpontaneous Recombinant Prion Protein Fibrils Revealed by Hydrogen/Deuterium Exchange

(2009) Vytautas Smirnovas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloids of Shuffled Prion Domains That Form Prions Have a Parallel In-Register β-Sheet Structure†

(2008) Frank Shewmaker et al.   BIOCHEMISTRY

Scrapie Prion Protein Structural Constraints Obtained by Limited Proteolysis and Mass Spectrometry

(2008) Gustavo Sajnani et al.   JOURNAL OF MOLECULAR BIOLOGY

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

(2008) Ryuichiro Atarashi et al.   NATURE METHODS

Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils

(2008) Valerie L. Sim et al.   NEUROBIOLOGY OF AGING

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS

Molecular conformation and dynamics of the Y145Stop variant of human prion protein in amyloid fibrils

(2008) J. J. Helmus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid of Rnq1p, the basis of the [PIN+] prion, has a parallel in-register  -sheet structure

(2008) R. B. Wickner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA