Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism

Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism

(2020) Owen Y. Chao et al.   NEUROPSYCHOPHARMACOLOGY

A Synaptic Perspective of Fragile X Syndrome and Autism Spectrum Disorders

(2019) Claudia Bagni et al.   NEURON

Anxiogenic-like behavior and deficient attention/working memory in rats expressing the human DISC1 gene

(2019) An-Li Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Behavioral assessments of BTBR T+Itpr3tf/J mice by tests of object attention and elevated open platform: Implications for an animal model of psychiatric comorbidity in autism

(2018) Owen Y. Chao et al.   BEHAVIOURAL BRAIN RESEARCH

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

(2018) Michael J. Gandal et al.   SCIENCE

Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain

(2018) Yi-Mei Yang et al.   MOLECULAR PSYCHIATRY

Neuroanatomical abnormalities in fragile X syndrome during the adolescent and young adult years

(2018) Gisela M. Sandoval et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Intranasal administration of dopamine attenuates unconditioned fear in that it reduces restraint-induced ultrasound vocalizations and escape from bright light

(2017) Teddy Talbot et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The BTBR mouse model of idiopathic autism – Current view on mechanisms

(2017) K.Z. Meyza et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Use of psychotropic drugs in patients with autism spectrum disorders: a systematic review

(2016) K. Jobski et al.   ACTA PSYCHIATRICA SCANDINAVICA

Splice form-dependent regulation of axonal arbor complexity by FMRP

(2016) Stephanie E. Zimmer et al.   Developmental Neurobiology

Intranasal Dopamine Reduces In Vivo [123I]FP-CIT Binding to Striatal Dopamine Transporter: Correlation with Behavioral Changes and Evidence for Pavlovian Conditioned Dopamine Response

(2016) Maria A. de Souza Silva et al.   Frontiers in Behavioral Neuroscience

Striatal Circuits as a Common Node for Autism Pathophysiology

(2016) Marc V. Fuccillo   Frontiers in Neuroscience

Hyperactivity and lack of social discrimination in the adolescent Fmr1 knockout mouse

(2015) Emilie M. Sørensen et al.   BEHAVIOURAL PHARMACOLOGY

Expression of fragile X mental retardation protein in neurons and glia of the developing and adult mouse brain

(2015) Shervin Gholizadeh et al.   BRAIN RESEARCH

Neurobiology of rodent self-grooming and its value for translational neuroscience

(2015) Allan V. Kalueff et al.   NATURE REVIEWS NEUROSCIENCE

A systematic review of molecular imaging (PET and SPECT) in autism spectrum disorder: Current state and future research opportunities

(2015) Nicole R. Zürcher et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum

(2014) L. A. Ruocco et al.   AMINO ACIDS

FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry

(2014) Giorgio La Fata et al.   NATURE NEUROSCIENCE

Intranasal dopamine treatment reinstates object-place memory in aged rats

(2014) S.V. Trossbach et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Dysfunctional dopaminergic neurotransmission in asocial BTBR mice

(2014) M Squillace et al.   Translational Psychiatry

Validation of operant social motivation paradigms using BTBR T+tf/J and C57BL/6J inbred mouse strains

(2014) Loren Martin et al.   Brain and Behavior

Functional and structural connectivity of frontostriatal circuitry in Autism Spectrum Disorder

(2013) Sonja Delmonte et al.   Frontiers in Human Neuroscience

Delayed myelination in a mouse model of fragile X syndrome

(2013) L. K. K. Pacey et al.   HUMAN MOLECULAR GENETICS

Autism

(2013) Meng-Chuan Lai et al.   LANCET

FMRP and myelin protein expression in oligodendrocytes

(2013) Anthony Giampetruzzi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder

(2013) P J Hamilton et al.   MOLECULAR PSYCHIATRY

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism

(2013) Luca Dodero et al.   PLoS One

Absence of social conditioned place preference in BTBR T+tf/J mice: Relevance for social motivation testing in rodent models of autism

(2012) Brandon L. Pearson et al.   BEHAVIOURAL BRAIN RESEARCH

Dampened dopamine-mediated neuromodulation in prefrontal cortex of fragile X mice

(2012) Kush Paul et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging

(2012) Jacob Ellegood et al.   NEUROIMAGE

Influence of stimulant-induced hyperactivity on social approach in the BTBR mouse model of autism

(2012) Jill L. Silverman et al.   NEUROPHARMACOLOGY

Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography

(2011) Marieke Langen et al.   CORTEX

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Modeling Autistic Features in Animals

(2011) PAUL H. PATTERSON   PEDIATRIC RESEARCH

Dopamine Release and Uptake Impairments and Behavioral Alterations Observed in Mice that Model Fragile X Mental Retardation Syndrome

(2010) Jenny L. Fulks et al.   ACS Chemical Neuroscience

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Dopamine in Motivational Control: Rewarding, Aversive, and Alerting

(2010) Ethan S. Bromberg-Martin et al.   NEURON

Physiology and Pharmacology of Striatal Neurons

(2009) Anatol C. Kreitzer   Annual Review of Neuroscience

Changes in the Developmental Trajectories of Striatum in Autism

(2009) Marieke Langen et al.   BIOLOGICAL PSYCHIATRY

The role of dopamine in bipolar disorder

(2009) David A Cousins et al.   BIPOLAR DISORDERS

Intranasal application of dopamine reduces activity and improves attention in Naples High Excitability rats that feature the mesocortical variant of ADHD

(2009) Lucia A. Ruocco et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

(2009) Shyeilla V. Dhuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Psychiatric Disorders in Children With Autism Spectrum Disorders: Prevalence, Comorbidity, and Associated Factors in a Population-Derived Sample

(2009) Emily Simonoff et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Effects of intranasally applied dopamine on behavioral asymmetries in rats with unilateral 6-hydroxydopamine lesions of the nigro-striatal tract

(2009) M.E. Pum et al.   NEUROSCIENCE

A Dopaminergic Axon Lattice in the Striatum and Its Relationship with Cortical and Thalamic Terminals

(2008) J. Moss et al.   JOURNAL OF NEUROSCIENCE

FMRP Acts as a Key Messenger for Dopamine Modulation in the Forebrain

(2008) Hansen Wang et al.   NEURON

Behavioral Actions of Intranasal Application of Dopamine: Effects on Forced Swimming, Elevated Plus-Maze and Open Field Parameters

(2008) Tim E. Buddenberg et al.   NEUROPSYCHOBIOLOGY

Animal models of anxiety: do I need multiple tests?

(2008) André Ramos   TRENDS IN PHARMACOLOGICAL SCIENCES

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR

Intranasal dopamine application increases dopaminergic activity in the neostriatum and nucleus accumbens and enhances motor activity in the open field

(2007) M.A. De Souza Silva et al.   SYNAPSE