Striatal Circuits as a Common Node for Autism Pathophysiology

Learning From Animal Models of Obsessive-Compulsive Disorder

(2016) Patricia Monteiro et al.   BIOLOGICAL PSYCHIATRY

From Synapses to Behavior: What Rodent Models Can Tell Us About Neuropsychiatric Disease

(2016) Marc V. Fuccillo et al.   BIOLOGICAL PSYCHIATRY

The Nucleus Accumbens: An Interface Between Cognition, Emotion, and Action

(2015) Stan B. Floresco   Annual Review of Psychology

Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits

(2015) Talia N. Lerner et al.   CELL

Striatal circuits, habits, and implications for obsessive–compulsive disorder

(2015) Eric Burguière et al.   CURRENT OPINION IN NEUROBIOLOGY

Synchrony in schizophrenia: a window into circuit-level pathophysiology

(2015) Timothy J Spellman et al.   CURRENT OPINION IN NEUROBIOLOGY

Autism spectrum disorders: from genes to neurobiology

(2015) A Jeremy Willsey et al.   CURRENT OPINION IN NEUROBIOLOGY

DISSECTING OCD CIRCUITS: FROM ANIMAL MODELS TO TARGETED TREATMENTS

(2015) Susanne E. Ahmari et al.   DEPRESSION AND ANXIETY

Feedforward and Feedback Motor Control Abnormalities Implicate Cerebellar Dysfunctions in Autism Spectrum Disorder

(2015) M. W. Mosconi et al.   JOURNAL OF NEUROSCIENCE

Impaired Presynaptic Long-Term Potentiation in the Anterior Cingulate Cortex of Fmr1 Knock-out Mice

(2015) K. Koga et al.   JOURNAL OF NEUROSCIENCE

The 16p11.2 Deletion Mouse Model of Autism Exhibits Altered Cortical Progenitor Proliferation and Brain Cytoarchitecture Linked to the ERK MAPK Pathway

(2015) J. Pucilowska et al.   JOURNAL OF NEUROSCIENCE

The striatum multiplexes contextual and kinematic information to constrain motor habits execution

(2015) Pavel E Rueda-Orozco et al.   NATURE NEUROSCIENCE

Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion

(2015) Di Tian et al.   NATURE NEUROSCIENCE

Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections

(2015) Yonatan M Kupchik et al.   NATURE NEUROSCIENCE

Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms

(2015) Marc V. Fuccillo et al.   NEURON

Action control processes in autism spectrum disorder – Insights from a neurobiological and neuroanatomical perspective

(2015) Witold X. Chmielewski et al.   PROGRESS IN NEUROBIOLOGY

A New Framework for Cortico-Striatal Plasticity: Behavioural Theory Meets In Vitro Data at the Reinforcement-Action Interface

(2015) Kevin N. Gurney et al.   PLOS BIOLOGY

Whole-Brain Mapping of Inputs to Projection Neurons and Cholinergic Interneurons in the Dorsal Striatum

(2015) Qingchun Guo et al.   PLoS One

A Translational Neuroscience Approach to Understanding the Development of Social Anxiety Disorder and Its Pathophysiology

(2014) Andrew S. Fox et al.   AMERICAN JOURNAL OF PSYCHIATRY

Identifying novel interventional strategies for psychiatric disorders: integrating genomics, ‘enviromics’ and gene-environment interactions in valid preclinical models

(2014) Caitlin E McOmish et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

(2014) Patrick E. Rothwell et al.   CELL

Neurobiological foundations of multisensory integration in people with autism spectrum disorders: the role of the medial prefrontal cortex

(2014) Sonia Martínez-Sanchis   Frontiers in Human Neuroscience

Extinction of an instrumental response: a cognitive behavioral assay inFmr1knockout mice

(2014) M. S. Sidorov et al.   GENES BRAIN AND BEHAVIOR

Deficient tonic GABAergic conductance and synaptic balance in the fragile X syndrome amygdala

(2014) Brandon S. Martin et al.   JOURNAL OF NEUROPHYSIOLOGY

New Roles for the External Globus Pallidus in Basal Ganglia Circuits and Behavior

(2014) A. H. Gittis et al.   JOURNAL OF NEUROSCIENCE

The Acquisition of Goal-Directed Actions Generates Opposing Plasticity in Direct and Indirect Pathways in Dorsomedial Striatum

(2014) Q. Shan et al.   JOURNAL OF NEUROSCIENCE

Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission

(2014) T. Karayannis et al.   NATURE

Genotype to phenotype relationships in autism spectrum disorders

(2014) Jonathan Chang et al.   NATURE NEUROSCIENCE

The Cerebellum, Sensitive Periods, and Autism

(2014) Samuel S.-H. Wang et al.   NEURON

Emergence of Context-Dependent Variability across a Basal Ganglia Network

(2014) Sarah C. Woolley et al.   NEURON

Two-phase model of the basal ganglia: implications for discontinuous control of the motor system

(2014) J. Lisman   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Attention as an effect not a cause

(2014) Richard J. Krauzlis et al.   TRENDS IN COGNITIVE SCIENCES

A de novo convergence of autism genetics and molecular neuroscience

(2014) Niklas Krumm et al.   TRENDS IN NEUROSCIENCES

Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome

(2014) Thomas Portmann et al.   Cell Reports

Changes in the Development of Striatum Are Involved in Repetitive Behavior in Autism

(2013) Marieke Langen et al.   BIOLOGICAL PSYCHIATRY

Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism

(2013) A. Jeremy Willsey et al.   CELL

Altered neural connectivity in excitatory and inhibitory cortical circuits in autism

(2013) Basilis Zikopoulos et al.   Frontiers in Human Neuroscience

Progress in understanding mood disorders: optogenetic dissection of neural circuits

(2013) S. Lammel et al.   GENES BRAIN AND BEHAVIOR

Direct-Pathway Striatal Neurons Regulate the Retention of Decision-Making Strategies

(2013) S. M. Ferguson et al.   JOURNAL OF NEUROSCIENCE

A Target Cell-Specific Role for Presynaptic Fmr1 in Regulating Glutamate Release onto Neocortical Fast-Spiking Inhibitory Neurons

(2013) A. B. Patel et al.   JOURNAL OF NEUROSCIENCE

Concurrent activation of striatal direct and indirect pathways during action initiation

(2013) Guohong Cui et al.   NATURE

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

(2013) Gül Dölen et al.   NATURE

The dorsomedial striatum encodes net expected return, critical for energizing performance vigor

(2013) Alice Y Wang et al.   NATURE NEUROSCIENCE

Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use

(2013) Roland Bock et al.   NATURE NEUROSCIENCE

Differential Innervation of Direct- and Indirect-Pathway Striatal Projection Neurons

(2013) Nicholas R. Wall et al.   NEURON

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Saccade Adaptation Abnormalities Implicate Dysfunction of Cerebellar-Dependent Learning Mechanisms in Autism Spectrum Disorders (ASD)

(2013) Matthew W. Mosconi et al.   PLoS One

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

(2013) E. Burguiere et al.   SCIENCE

Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior

(2013) S. E. Ahmari et al.   SCIENCE

Motor thalamus integration of cortical, cerebellar and basal ganglia information: implications for normal and parkinsonian conditions

(2013) Clémentine Bosch-Bouju et al.   Frontiers in Computational Neuroscience

Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions

(2013) Christina M. Gremel et al.   Nature Communications

Consensus Paper: Pathological Role of the Cerebellum in Autism

(2012) S. Hossein Fatemi et al.   CEREBELLUM

Updating dopamine reward signals

(2012) Wolfram Schultz   CURRENT OPINION IN NEUROBIOLOGY

Social ‘wanting’ dysfunction in autism: neurobiological underpinnings and treatment implications

(2012) Gregor Kohls et al.   Journal of Neurodevelopmental Disorders

Amygdala Central Nucleus Interacts with Dorsolateral Striatum to Regulate the Acquisition of Habits

(2012) N. W. Lingawi et al.   JOURNAL OF NEUROSCIENCE

Integrative Approaches Utilizing Oxytocin to Enhance Prosocial Behavior: From Animal and Human Social Behavior to Autistic Social Dysfunction

(2012) H. Yamasue et al.   JOURNAL OF NEUROSCIENCE

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

(2012) Michael J. Schmeisser et al.   NATURE

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

(2012) Hyejung Won et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Transient stimulation of distinct subpopulations of striatal neurons mimics changes in action value

(2012) Lung-Hao Tai et al.   NATURE NEUROSCIENCE

Distinct roles for direct and indirect pathway striatal neurons in reinforcement

(2012) Alexxai V Kravitz et al.   NATURE NEUROSCIENCE

Action Selection and Action Value in Frontal-Striatal Circuits

(2012) Moonsang Seo et al.   NEURON

Dopaminergic Modulation of Synaptic Transmission in Cortex and Striatum

(2012) Nicolas X. Tritsch et al.   NEURON

Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development

(2012) G. R. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reward system dysfunction in autism spectrum disorders

(2012) Gregor Kohls et al.   Social Cognitive and Affective Neuroscience

Contributions of the striatum to learning, motivation, and performance: an associative account

(2012) Mimi Liljeholm et al.   TRENDS IN COGNITIVE SCIENCES

Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome

(2012) Kwang-Mook Jung et al.   Nature Communications

Social and monetary reward processing in autism spectrum disorders

(2012) Sonja Delmonte et al.   Molecular Autism

Age dependent forebrain structural changes in mice deficient in the autism associated gene Met tyrosine kinase

(2012) Jacob M. Smith et al.   NeuroImage-Clinical

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Basal ganglia morphometry and repetitive behavior in young children with autism spectrum disorder

(2011) Annette Estes et al.   Autism Research

Aberrant Striatal Functional Connectivity in Children with Autism

(2011) Adriana Di Martino et al.   BIOLOGICAL PSYCHIATRY

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

Evolutionary Conservation of the Basal Ganglia as a Common Vertebrate Mechanism for Action Selection

(2011) Marcus Stephenson-Jones et al.   CURRENT BIOLOGY

Brain structure anomalies in autism spectrum disorder-a meta-analysis of VBM studies using anatomic likelihood estimation

(2011) Thomas Nickl-Jockschat et al.   HUMAN BRAIN MAPPING

Circuit-Specific Intracortical Hyperconnectivity in Mice with Deletion of the Autism-Associated Met Receptor Tyrosine Kinase

(2011) S. Qiu et al.   JOURNAL OF NEUROSCIENCE

Functional Connectome of the Striatal Medium Spiny Neuron

(2011) N. Chuhma et al.   JOURNAL OF NEUROSCIENCE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Genetic disruption of Met signaling impairs GABAergic striatal development and cognition

(2011) G.J. Martins et al.   NEUROSCIENCE

A hypothesis for basal ganglia-dependent reinforcement learning in the songbird

(2011) M.S. Fee et al.   NEUROSCIENCE

Serotonergic action on dorsal striatal function

(2011) Brian N. Mathur et al.   PARKINSONISM & RELATED DISORDERS

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

(2011) D. D. Krueger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

(2011) G. Horev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

(2011) M. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inputs to the Dorsal Striatum of the Mouse Reflect the Parallel Circuit Architecture of the Forebrain

(2011) Weixing X. Pan et al.   Frontiers in Neuroanatomy

Significance of Input Correlations in Striatal Function

(2011) Man Yi Yim et al.   PLoS Computational Biology

Learning and cognitive flexibility: frontostriatal function and monoaminergic modulation

(2010) Angie A Kehagia et al.   CURRENT OPINION IN NEUROBIOLOGY

Striatal Dopamine Modulates Basal Ganglia Output and Regulates Social Context-Dependent Behavioral Variability through D1 Receptors

(2010) A. Leblois et al.   JOURNAL OF NEUROSCIENCE

Changes in Prefrontal Axons May Disrupt the Network in Autism

(2010) B. Zikopoulos et al.   JOURNAL OF NEUROSCIENCE

The Sensorimotor Striatum Is Necessary for Serial Order Learning

(2010) H. H. Yin   JOURNAL OF NEUROSCIENCE

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Thalamic Gating of Corticostriatal Signaling by Cholinergic Interneurons

(2010) Jun B. Ding et al.   NEURON

Selective Activation of Striatal Fast-Spiking Interneurons during Choice Execution

(2010) Gregory J. Gage et al.   NEURON

Distinct Roles of Synaptic Transmission in Direct and Indirect Striatal Pathways to Reward and Aversive Behavior

(2010) Takatoshi Hikida et al.   NEURON

The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens

(2010) Scott J. Russo et al.   TRENDS IN NEUROSCIENCES

Cerebellum and Nonmotor Function

(2009) Peter L. Strick et al.   Annual Review of Neuroscience

Changes in the Developmental Trajectories of Striatum in Autism

(2009) Marieke Langen et al.   BIOLOGICAL PSYCHIATRY

Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

(2009) Jin Nakatani et al.   CELL

Dynamic Encoding of Action Selection by the Medial Striatum

(2009) E. Y. Kimchi et al.   JOURNAL OF NEUROSCIENCE

Frontal–striatal abnormalities underlying behaviours in the compulsive–impulsive spectrum

(2009) Odile A. van den Heuvel et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action

(2009) Bernard W Balleine et al.   NEUROPSYCHOPHARMACOLOGY

Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene

(2008) Maricela Alarcón et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Common Genetic Variant in the Neurexin Superfamily Member CNTNAP2 Increases Familial Risk of Autism

(2008) Dan E. Arking et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular Cytogenetic Analysis and Resequencing of Contactin Associated Protein-Like 2 in Autism Spectrum Disorders

(2008) Betul Bakkaloglu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cortico-limbic-striatal circuits subserving different forms of cost-benefit decision making

(2008) S. B. Floresco et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Striatal Plasticity and Basal Ganglia Circuit Function

(2008) Anatol C. Kreitzer et al.   NEURON

Association between Microdeletion and Microduplication at 16p11.2 and Autism

(2008) Lauren A. Weiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deletion 22q13.3 syndrome

(2008) Mary C Phelan   Orphanet Journal of Rare Diseases

The Neural Circuitry Mediating Shifts in Behavioral Response and Cognitive Set in Autism

(2007) Keith M. Shafritz et al.   BIOLOGICAL PSYCHIATRY

Abnormal Striatal GABA Transmission in the Mouse Model for the Fragile X Syndrome

(2007) Diego Centonze et al.   BIOLOGICAL PSYCHIATRY