The dynamics of biomarkers across the clinical spectrum of Alzheimer’s disease

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

(2019) Oliver Preische et al.   NATURE MEDICINE

Education and cognitive reserve in old age

(2019) Robert S. Wilson et al.   NEUROLOGY

Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease

(2019) Niklas Mattsson et al.   JAMA Neurology

CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

(2018) Oskar Hansson et al.   Alzheimers & Dementia

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Data-driven models of dominantly-inherited Alzheimer’s disease progression

(2018) Neil P Oxtoby et al.   BRAIN

The development of a stochastic mathematical model of Alzheimer’s disease to help improve the design of clinical trials of potential treatments

(2018) Christoforos Hadjichrysanthou et al.   PLoS One

Quantifying the Pathophysiological Timeline of Alzheimer's Disease

(2018) Eric Yang et al.   JOURNAL OF ALZHEIMERS DISEASE

How early can we diagnose Alzheimer disease (and is it sufficient)?

(2018) Ronald C. Petersen   NEUROLOGY

Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer’s disease

(2018) Piotr Lewczuk et al.   Alzheimers Research & Therapy

Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies

(2018) Christoforos Hadjichrysanthou et al.   JOURNAL OF ALZHEIMERS DISEASE

Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons

(2017) Michael C. Donohue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Bayesian latent time joint mixed effect models for multicohort longitudinal data

(2017) Dan Li et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

On the path to 2025: understanding the Alzheimer’s disease continuum

(2017) Paul S. Aisen et al.   Alzheimers Research & Therapy

Association of Longitudinal Cognitive Decline With Amyloid Burden in Middle-aged and Older Adults

(2017) Michelle E. Farrell et al.   JAMA Neurology

Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease

(2017) Niklas Mattsson et al.   JAMA Neurology

Time to Amyloid Positivity and Preclinical Changes in Brain Metabolism, Atrophy, and Cognition: Evidence for Emerging Amyloid Pathology in Alzheimer's Disease

(2017) Philip S. Insel et al.   Frontiers in Neuroscience

Conceptual Evolution in Alzheimer's Disease: Implications for Understanding the Clinical Phenotype of Progressive Neurodegenerative Disease

(2017) Gregory A. Jicha et al.   JOURNAL OF ALZHEIMERS DISEASE

ADCOMS: a composite clinical outcome for prodromal Alzheimer's disease trials

(2016) Jinping Wang et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression

(2016) Henrik Zetterberg et al.   JAMA Neurology

Age-dependent effects ofAPOEε4 in preclinical Alzheimer's disease

(2016) Luke W. Bonham et al.   Annals of Clinical and Translational Neurology

A simulation system for biomarker evolution in neurodegenerative disease

(2015) Alexandra L. Young et al.   MEDICAL IMAGE ANALYSIS

Estimating long-term multivariate progression from short-term data

(2014) Michael C. Donohue et al.   Alzheimers & Dementia

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

(2014) Bruno Dubois et al.   LANCET NEUROLOGY

Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis

(2014) D. C. Ryman et al.   NEUROLOGY

Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease

(2014) A. M. Fagan et al.   Science Translational Medicine

The Preclinical Alzheimer Cognitive Composite

(2014) Michael C. Donohue et al.   JAMA Neurology

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Plasma tau levels in Alzheimer's disease

(2013) Henrik Zetterberg et al.   Alzheimers Research & Therapy

Amyloid deposition, hypometabolism, and longitudinal cognitive decline

(2012) Susan M. Landau et al.   ANNALS OF NEUROLOGY

Cerebrospinal Fluid Levels ofβ-Amyloid 1-42, but Not of Tau, Are Fully Changed Already 5 to 10 Years Before the Onset of Alzheimer Dementia

(2012) Peder Buchhave   ARCHIVES OF GENERAL PSYCHIATRY

Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan

(2012) Kristen M. Kennedy et al.   NEUROIMAGE

A computational neurodegenerative disease progression score: Method and results with the Alzheimer's disease neuroimaging initiative cohort

(2012) Bruno M. Jedynak et al.   NEUROIMAGE

Subjective cognitive complaints and amyloid burden in cognitively normal older individuals

(2012) Rebecca E. Amariglio et al.   NEUROPSYCHOLOGIA

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Education and Dementia in the Context of the Cognitive Reserve Hypothesis: A Systematic Review with Meta-Analyses and Qualitative Analyses

(2012) Xiangfei Meng et al.   PLoS One

Relationship Between Education and Dementia

(2011) Emily Schoenhofen Sharp et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Clifford R. Jack et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Longitudinal Change of Biomarkers in Cognitive Decline

(2011) Raymond Y. Lo   ARCHIVES OF NEUROLOGY

The Dynamics of Cortical and Hippocampal Atrophy in Alzheimer Disease

(2011) Mert R. Sabuncu   ARCHIVES OF NEUROLOGY

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

(2011) Christopher M. Clark   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core

(2010) William J. Jagust et al.   Alzheimers & Dementia

Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease

(2010) Annika Thorsell et al.   BRAIN RESEARCH

Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging

(2010) Christopher C. Rowe et al.   NEUROBIOLOGY OF AGING

APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

(2009) John C. Morris et al.   ANNALS OF NEUROLOGY

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Alzheimer's Disease Neuroimaging Initiative (ADNI): Clinical characterization

(2009) R. C. Petersen et al.   NEUROLOGY

Prodromal Alzheimer's disease: Successive emergence of the clinical symptoms

(2008) Hélène Amieva et al.   ANNALS OF NEUROLOGY

11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment

(2008) Clifford R. Jack et al.   BRAIN