Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoarthritis pain in a rat model of osteoarthritis

MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis

(2019) Shipin Zhang et al.   BIOMATERIALS

Therapeutic options for targeting inflammatory osteoarthritis pain

(2019) Philip G. Conaghan et al.   Nature Reviews Rheumatology

Exosomal KLF3-AS1 from hMSCs promoted cartilage repair and chondrocyte proliferation in osteoarthritis

(2018) Yubao Liu et al.   BIOCHEMICAL JOURNAL

MSC-derived exosomes promote proliferation and inhibit apoptosis of chondrocytes via lncRNA-KLF3-AS1/miR-206/GIT1 axis in osteoarthritis

(2018) Yubao Liu et al.   CELL CYCLE

Pathogenic or Therapeutic Extracellular Vesicles in Rheumatic Diseases: Role of Mesenchymal Stem Cell-Derived Vesicles

(2017) Stella Cosenza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis

(2017) Stella Cosenza et al.   Scientific Reports

Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

(2017) Yu Zhu et al.   Stem Cell Research & Therapy

Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix

(2017) Yafei Wang et al.   Stem Cell Research & Therapy

Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model

(2017) Shi-Cong Tao et al.   Theranostics

Osteoarthritis: toward a comprehensive understanding of pathological mechanism

(2017) Di Chen et al.   Bone Research

Exosomes for repair, regeneration and rejuvenation

(2016) Joydeep Basu et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Human Endothelial Colony-Forming Cells Protect against Acute Kidney Injury

(2015) Dylan Burger et al.   AMERICAN JOURNAL OF PATHOLOGY

Using exosomes, naturally-equipped nanocarriers, for drug delivery

(2015) Elena V. Batrakova et al.   JOURNAL OF CONTROLLED RELEASE

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

A family history of knee joint replacement increases the progression of knee radiographic osteoarthritis and medial tibial cartilage volume loss over 10 years

(2015) H.I. Khan et al.   OSTEOARTHRITIS AND CARTILAGE

Correction: Survival and Biodistribution of Xenogenic Adipose Mesenchymal Stem Cells Is Not Affected by the Degree of Inflammation in Arthritis

(2015)   PLoS One

Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice

(2015) Guo-wen Hu et al.   Stem Cell Research & Therapy

Mesenchymal stem cells reduce pain but not degenerative changes in a mono-iodoacetate rat model of osteoarthritis

(2014) Gerben M. van Buul et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation

(2014) Meilang Xue et al.   RHEUMATOLOGY

Neuropathic pain in osteoarthritis: A review of pathophysiological mechanisms and implications for treatment

(2014) Theodoros Dimitroulas et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Induction of an Inflammatory and Prodegradative Phenotype in Autologous Fibroblast-like Synoviocytes by the Infrapatellar Fat Pad From Patients With Knee Osteoarthritis

(2014) Florent Eymard et al.   Arthritis & Rheumatology

Elevation of Serum Tumor Necrosis Factor α in Patients with Periprosthetic Osteolysis: A Case-Control Study

(2013) R. Krishna Chaganti et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis

(2013) P.I. Mapp et al.   OSTEOARTHRITIS AND CARTILAGE

Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis

(2013) Marie Maumus et al.   Stem Cell Research

Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model

(2013) Giovanna Desando et al.   ARTHRITIS RESEARCH & THERAPY

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Pain Processing in the Human Nervous System

(2012) Eric L. Garland   PRIMARY CARE

Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy

(2012) Serena Rubina Baglio et al.   Frontiers in Physiology

Physiology and pathophysiology of matrix metalloproteases

(2010) T. Klein et al.   AMINO ACIDS

Nociceptors: the sensors of the pain pathway

(2010) Adrienne E. Dubin et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat

(2010) N. Gerwin et al.   OSTEOARTHRITIS AND CARTILAGE

Gait analysis and pain response of two rodent models of osteoarthritis

(2010) C.E. Ferland et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

(2009) R.F. Loeser   OSTEOARTHRITIS AND CARTILAGE

The Interleukin 1β Pathway in the Pathogenesis of Osteoarthritis

(2008) Massoud Daheshia et al.   JOURNAL OF RHEUMATOLOGY