Neuroprotective Effect of Mesenchymal Stromal Cell-Derived Extracellular Vesicles Against Cerebral Ischemia-Reperfusion-Induced Neural Functional Injury: A Pivotal Role for AMPK and JAK2/STAT3/NF-κB Signaling Pathway Modulation
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Title
Neuroprotective Effect of Mesenchymal Stromal Cell-Derived Extracellular Vesicles Against Cerebral Ischemia-Reperfusion-Induced Neural Functional Injury: A Pivotal Role for AMPK and JAK2/STAT3/NF-κB Signaling Pathway Modulation
Authors
Keywords
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Journal
Drug Design Development and Therapy
Volume Volume 14, Issue -, Pages 2865-2876
Publisher
Informa UK Limited
Online
2020-07-20
DOI
10.2147/dddt.s248892
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Note: Only part of the references are listed.- Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats
- (2020) Jing Yu et al. Oxidative Medicine and Cellular Longevity
- Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis
- (2019) Xin Zhou et al. BIOMEDICINE & PHARMACOTHERAPY
- The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
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- (2019) Fei Wei et al. Journal of Tissue Engineering and Regenerative Medicine
- miRNA-181a over-expression in mesenchymal stem cell-derived exosomes influenced inflammatory response after myocardial ischemia-reperfusion injury
- (2019) Zilun Wei et al. LIFE SCIENCES
- Hydrogel-Mediated Sustained Systemic Delivery of Mesenchymal Stem Cell-Derived Extracellular Vesicles Improves Hepatic Regeneration in Chronic Liver Failure
- (2019) Soura Mardpour et al. ACS Applied Materials & Interfaces
- Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway
- (2019) Chongyang Ma et al. BMC Complementary and Alternative Medicine
- Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles
- (2019) Sylwia Dabrowska et al. Journal of Neuroinflammation
- Human bone marrow mesenchymal stem cell-derived extracellular vesicles attenuate neuroinflammation evoked by focal brain injury in rats
- (2019) Sylwia Dabrowska et al. Journal of Neuroinflammation
- Salvinorin A moderates postischemic brain injury by preserving endothelial mitochondrial function via AMPK/Mfn2 activation
- (2019) Haiping Dong et al. EXPERIMENTAL NEUROLOGY
- Theanine attenuates hippocampus damage of rat cerebral ischemia-reperfusion injury by inhibiting HO-1 expression and activating ERK1/2 pathway
- (2019) Jing Zhao et al. LIFE SCIENCES
- Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation
- (2019) Lili Liu et al. LIFE SCIENCES
- The roles of extracellular vesicle microRNAs in the central nervous system
- (2018) Stephanie N. Blandford et al. GLIA
- Study on the mechanism of JAK2/STAT3 signaling pathway-mediated inflammatory reaction after cerebral ischemia
- (2018) Yuquan Wu et al. Molecular Medicine Reports
- Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT pathway
- (2018) Yaping Li et al. BMC CANCER
- Mesenchymal stem cell-derived extracellular vesicles: a glimmer of hope in treating Alzheimer’s disease
- (2017) Lee Chuen Liew et al. INTERNATIONAL IMMUNOLOGY
- Cortical spreading depression preconditioning mediates neuroprotection against ischemic stroke by inducing AMP-activated protein kinase-dependent autophagy in a rat cerebral ischemic/reperfusion injury model
- (2017) Pingping Shen et al. JOURNAL OF NEUROCHEMISTRY
- Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NF-κB and JAK–STAT Pathway
- (2017) Qasim Alhadidi et al. MOLECULAR NEUROBIOLOGY
- Inhibition of cerebral ischemia/reperfusion injury-induced apoptosis: nicotiflorin and JAK2/STAT3 pathway
- (2017) Guang-qiang Hu et al. Neural Regeneration Research
- Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus
- (2017) Qianfa Long et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fingolimod Protects Against Ischemic White Matter Damage by Modulating Microglia Toward M2 Polarization via STAT3 Pathway
- (2017) Chuan Qin et al. STROKE
- White Matter Repair After Extracellular Vesicles Administration in an Experimental Animal Model of Subcortical Stroke
- (2017) Laura Otero-Ortega et al. Scientific Reports
- MALAT1 in human adipose stem cells modulates survival and alternative splicing of PKCδII in HT22 cells
- (2016) Ghattas El Bassit et al. ENDOCRINOLOGY
- The neuroprotection of Sinomenine against ischemic stroke in mice by suppressing NLRP3 inflammasome via AMPK signaling
- (2016) Jing Qiu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Cause-specific mortality for 240 causes in China during 1990–2013: a systematic subnational analysis for the Global Burden of Disease Study 2013
- (2016) Maigeng Zhou et al. LANCET
- Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons
- (2016) Yi Zhang et al. MOLECULAR NEUROBIOLOGY
- Preactivated and Disaggregated Shape-Changed Platelets Protected Against Acute Respiratory Distress Syndrome Complicated by Sepsis Through Inflammation Suppression
- (2016) Yuan-Ji Day et al. SHOCK
- Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia
- (2016) Daan R.M.G. Ophelders et al. Stem Cells Translational Medicine
- Schizandrin A Inhibits Microglia-Mediated Neuroninflammation through Inhibiting TRAF6-NF-κB and Jak2-Stat3 Signaling Pathways
- (2016) Fangjiao Song et al. PLoS One
- Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression
- (2015) Thorsten R. Doeppner et al. Stem Cells Translational Medicine
- Complementary and Alternative Medicine on Wikipedia: Opportunities for Improvement
- (2014) Malcolm Koo Evidence-based Complementary and Alternative Medicine
- Astragaloside IV Alleviates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats
- (2014) Anwen Shao et al. International Journal of Medical Sciences
- Burden of Stroke in Puerto Rico
- (2014) Juan Zevallos et al. International Journal of Stroke
- Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype
- (2014) D. Sag et al. JOURNAL OF IMMUNOLOGY
- Butein inhibits NF-κB activation and reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats
- (2013) Ming Lu et al. NEUROSCIENCE LETTERS
- Sesquiterpene dimer (DSF-52) from Artemisia argyi inhibits microglia-mediated neuroinflammation via suppression of NF-κB, JNK/p38 MAPKs and Jak2/Stat3 signaling pathways
- (2013) Ke-Wu Zeng et al. PHYTOMEDICINE
- MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles
- (2013) Hongqi Xin et al. STEM CELLS
- Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microglia
- (2012) Sonja Johann et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The potential role of JAK2/STAT3 pathway on the anti-apoptotic effect of recombinant human erythropoietin (rhEPO) after experimental traumatic brain injury of rats
- (2011) Jinbing Zhao et al. CYTOKINE
- The role of microvesicles in tissue repair
- (2011) Ciro Tetta et al. Organogenesis
- Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
- (2009) S. Bruno et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The Nuclear Factor NF- B Pathway in Inflammation
- (2009) T. Lawrence Cold Spring Harbor Perspectives in Biology
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