Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

25 years of advances in the definition, classification and treatment of status epilepticus

(2017) Eugen Trinka et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Status Epilepticus

(2016) Danya Khoujah et al.   EMERGENCY MEDICINE CLINICS OF NORTH AMERICA

A reduced susceptibility to chemoconvulsant stimulation in adenylyl cyclase 8 knockout mice

(2016) Xia Chen et al.   EPILEPSY RESEARCH

Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate?

(2016) Sinéad M. Ryan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus

(2016) Nicholas H. Varvel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmaceutical Rejuvenation of Age-Associated Decline in Spatial Memory

(2016) Andrew R. Mendelsohn et al.   REJUVENATION RESEARCH

Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling

(2016) Johnathon D. Anderson et al.   STEM CELLS

Status Epilepticus

(2016) Syndi Seinfeld et al.   Cold Spring Harbor Perspectives in Medicine

Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It

(2016) Dong-Ki Kim et al.   PLoS One

Discarded Wharton jelly of the human umbilical cord: a viable source for mesenchymal stromal cells

(2015) Nate Watson et al.   CYTOTHERAPY

Single versus combinatorial therapies in status epilepticus: Novel data from preclinical models

(2015) Wolfgang Löscher   EPILEPSY & BEHAVIOR

Immunity and inflammation in status epilepticus and its sequelae: possibilities for therapeutic application

(2015) Annamaria Vezzani et al.   Expert Review of Neurotherapeutics

Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles

(2015) Nina Heldring et al.   HUMAN GENE THERAPY

Using exosomes, naturally-equipped nanocarriers, for drug delivery

(2015) Elena V. Batrakova et al.   JOURNAL OF CONTROLLED RELEASE

Chromatographically isolated CD63+CD81+extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI

(2015) Dong-ki Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Prospects of Bone Marrow Mononuclear Cells and Mesenchymal Stem Cells for Treating Status Epilepticus and Chronic Epilepsy

(2015) Satish Agadi et al.   STEM CELLS

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

(2015) Donald G. Phinney et al.   Nature Communications

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline

(2015) Kyung-Ok Cho et al.   Nature Communications

Resveratrol Treatment after Status Epilepticus Restrains Neurodegeneration and Abnormal Neurogenesis with Suppression of Oxidative Stress and Inflammation

(2015) Vikas Mishra et al.   Scientific Reports

Immunity and inflammation in status epilepticus and its sequelae: possibilities for therapeutic application

(2015) Annamaria Vezzani et al.   Expert Review of Neurotherapeutics

hPSC-Derived Maturing GABAergic Interneurons Ameliorate Seizures and Abnormal Behavior in Epileptic Mice

(2014) Miles Cunningham et al.   Cell Stem Cell

Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: Can early neural stem cell grafting intervention provide protection?

(2014) Ashok K. Shetty   EPILEPSY & BEHAVIOR

Hippocampal granule cell pathology in epilepsy — A possible structural basis for comorbidities of epilepsy?

(2014) Michael S. Hester et al.   EPILEPSY & BEHAVIOR

The current landscape of adipose-derived stem cells in clinical applications

(2014) Ming Hui Lim et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells

(2014) Chiara Cossetti et al.   MOLECULAR CELL

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

(2014) Marco Prinz et al.   NATURE REVIEWS NEUROSCIENCE

A Bayesian tool for epilepsy diagnosis in the resource-poor world: Development and early validation

(2014) Victor Patterson et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Mesenchymal Stem Cell Population Derived from Human Pluripotent Stem Cells Displays Potent Immunomodulatory and Therapeutic Properties

(2014) Erin A. Kimbrel et al.   STEM CELLS AND DEVELOPMENT

Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness

(2014) Bharathi Hattiangady et al.   Frontiers in Behavioral Neuroscience

Fetal brain inflammation may prime hyperexcitability and behavioral dysfunction later in life

(2013) Annamaria Vezzani   ANNALS OF NEUROLOGY

Trafficking of NMDA receptors during status epilepticus: Therapeutic implications

(2013) Claude G. Wasterlain et al.   EPILEPSIA

A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches

(2013) Damir Janigro et al.   EPILEPSIA

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Blocking seizures with the diuretic bumetanide: Promises and pitfalls

(2012) Yehezkel Ben-Ari   EPILEPSIA

Defining “epileptogenesis” and identifying “antiepileptogenic targets” in animal models of acquired temporal lobe epilepsy is not as simple as it might seem

(2012) Robert S. Sloviter et al.   NEUROPHARMACOLOGY

Parvalbumin-positive CA1 interneurons are required for spatial working but not for reference memory

(2011) Andrew J Murray et al.   NATURE NEUROSCIENCE

Cytokines and epilepsy

(2011) Gang Li et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Pattern separation in the hippocampus

(2011) Michael A. Yassa et al.   TRENDS IN NEUROSCIENCES

Emerging Concepts in the Pathogenesis of Epilepsy and Epileptogenesis

(2009) Marc A. Dichter   ARCHIVES OF NEUROLOGY

Decreased neuronal differentiation of newly generated cells underlies reduced hippocampal neurogenesis in chronic temporal lobe epilepsy

(2009) Bharathi Hattiangady et al.   HIPPOCAMPUS

Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy

(2008) Ramkumar Kuruba et al.   EPILEPSY & BEHAVIOR