Small extracellular vesicles derived from human MSCs prevent allergic airway inflammation via immunomodulation on pulmonary macrophages

Small extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell-dominant allergic airway inflammation through delivery of miR-146a-5p

(2020) Shu-Bin Fang et al.   Journal of Extracellular Vesicles

Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation

(2018) Gareth R. Willis et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MSC exosome works through a protein-based mechanism of action

(2018) Wei Seong Toh et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Macrophage polarization and allergic asthma

(2018) Arjun Saradna et al.   Translational Research

Human iPSC-MSCs prevent steroid-resistant neutrophilic airway inflammation via modulating Th17 phenotypes

(2018) Shu-Bin Fang et al.   Stem Cell Research & Therapy

Human Gingiva-Derived Mesenchymal Stem Cells Modulate Monocytes/Macrophages and Alleviate Atherosclerosis

(2018) Ximei Zhang et al.   Frontiers in Immunology

Proteomic Signature of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles

(2018) Bas W. M. van Balkom et al.   PROTEOMICS

Connexin 43-Mediated Mitochondrial Transfer of iPSC-MSCs Alleviates Asthma Inflammation

(2018) Yin Yao et al.   Stem Cell Reports

Human asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL-10+ M2-like macrophages around airways compared with healthy airways

(2017) Christina Draijer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

(2017) Alexander V. Misharin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human adipose tissue mesenchymal stromal cells and their extracellular vesicles act differentially on lung mechanics and inflammation in experimental allergic asthma

(2017) Ligia Lins de Castro et al.   Stem Cell Research & Therapy

Effects of mesenchymal stem cells from human induced pluripotent stem cells on differentiation, maturation, and function of dendritic cells

(2017) Wen-Xiang Gao et al.   Stem Cell Research & Therapy

Alternative Macrophage Activation Is Increased in Asthma

(2016) Pierre-Olivier Girodet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mesenchymal Stem Cells Induce Suppressive Macrophages Through Phagocytosis in a Mouse Model of Asthma

(2016) Faouzi Braza et al.   STEM CELLS

Distinct macrophage phenotypes in allergic and nonallergic lung inflammation

(2015) Patricia Robbe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Chromatographically isolated CD63+CD81+extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI

(2015) Dong-ki Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal stem cell exosomes

(2015) Ruenn Chai Lai et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Insensitivity of Human iPS Cells-Derived Mesenchymal Stem Cells to Interferon-γ-induced HLA Expression Potentiates Repair Efficiency of Hind Limb Ischemia in Immune Humanized NOD Scid Gamma Mice

(2015) Yue-Qi Sun et al.   STEM CELLS

Pulmonary macrophages: key players in the innate defence of the airways

(2015) Adam J Byrne et al.   THORAX

Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles AmelioratesAspergillusHyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice

(2015) Fernanda F. Cruz et al.   Stem Cells Translational Medicine

Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge

(2014) S. A. Mathie et al.   ALLERGY

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

Resident Alveolar Macrophages Suppress, whereas Recruited Monocytes Promote, Allergic Lung Inflammation in Murine Models of Asthma

(2014) Zbigniew Zasłona et al.   JOURNAL OF IMMUNOLOGY

Alveolar Macrophages Are Critical for the Inhibition of Allergic Asthma by Mesenchymal Stromal Cells

(2013) L. J. Mathias et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis

(2012) Q. L. Fu et al.   ALLERGY

Exosomes Mediate the Cytoprotective Action of Mesenchymal Stromal Cells on Hypoxia-Induced Pulmonary Hypertension

(2012) Changjin Lee et al.   CIRCULATION

Emerging roles of pulmonary macrophages in driving the development of severe asthma

(2012) M. Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Allergic Airway Inflammation in Mice

(2012) Yue-Qi Sun et al.   STEM CELLS

Asthma and Allergic Inflammation

(2010) Richard M. Locksley   CELL

Functional Mesenchymal Stem Cells Derived From Human Induced Pluripotent Stem Cells Attenuate Limb Ischemia in Mice

(2010) Qizhou Lian et al.   CIRCULATION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols