Human iPSC-MSCs prevent steroid-resistant neutrophilic airway inflammation via modulating Th17 phenotypes

Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma

(2017) Philip M. Hansbro et al.   IMMUNOLOGICAL REVIEWS

Bcl-2 inhibitors reduce steroid-insensitive airway inflammation

(2017) Bao-ping Tian et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Severe and Difficult-to-Treat Asthma in Adults

(2017) Elliot Israel et al.   NEW ENGLAND JOURNAL OF MEDICINE

The lncRNAs involved in mouse airway allergic inflammation following induced pluripotent stem cell-mesenchymal stem cell treatment

(2017) Shu-Yue Wang et al.   Stem Cell Research & Therapy

Effects of mesenchymal stem cells from human induced pluripotent stem cells on differentiation, maturation, and function of dendritic cells

(2017) Wen-Xiang Gao et al.   Stem Cell Research & Therapy

Review article: mesenchymal stromal cell therapy for inflammatory bowel diseases

(2016) C. Grégoire et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Translational opportunities for targeting the Th17 axis in acute graft-vs.-host disease

(2016) F Malard et al.   Mucosal Immunology

MicroRNAs Involved in Asthma After Mesenchymal Stem Cells Treatment

(2016) Guan-Nan Tang et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal stem cells and immunomodulation: current status and future prospects

(2016) F Gao et al.   Cell Death & Disease

Treatment of severe asthma: entering the era of targeted therapy

(2015) Amanda R van Buul et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

(2015) L Dejager et al.   Mucosal Immunology

Insensitivity of Human iPS Cells-Derived Mesenchymal Stem Cells to Interferon-γ-induced HLA Expression Potentiates Repair Efficiency of Hind Limb Ischemia in Immune Humanized NOD Scid Gamma Mice

(2015) Yue-Qi Sun et al.   STEM CELLS

TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice

(2014) L. McKinley et al.   JOURNAL OF IMMUNOLOGY

Trif-dependent induction of Th17 immunity by lung dendritic cells

(2014) B J Hsia et al.   Mucosal Immunology

Mesenchymal Stromal Cells MediateAspergillusHyphal Extract-Induced Allergic Airway Inflammation by Inhibition of the Th17 Signaling Pathway

(2014) Melissa J. Lathrop et al.   Stem Cells Translational Medicine

Randomized, Double-Blind, Placebo-controlled Study of Brodalumab, a Human Anti–IL-17 Receptor Monoclonal Antibody, in Moderate to Severe Asthma

(2013) William W. Busse et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

(2013) Wendy C. Moore et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis

(2012) Q. L. Fu et al.   ALLERGY

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Allergic Airway Inflammation in Mice

(2012) Yue-Qi Sun et al.   STEM CELLS

IL-35 production by inducible costimulator (ICOS)–positive regulatory T cells reverses established IL-17–dependent allergic airways disease

(2011) Gregory S. Whitehead et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dopamine D1-Like Receptor Antagonist Attenuates Th17-Mediated Immune Response and Ovalbumin Antigen-Induced Neutrophilic Airway Inflammation

(2011) K. Nakagome et al.   JOURNAL OF IMMUNOLOGY

TNF-  from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

(2011) M. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of hematopoietic cell development and function by Stat3

(2010) Pamela et al.   Frontiers in Bioscience-Landmark

Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma

(2010) Stephane Lajoie et al.   NATURE IMMUNOLOGY

Allergic Sensitization through the Airway Primes Th17-dependent Neutrophilia and Airway Hyperresponsiveness

(2009) Rhonda H. Wilson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TH17-associated cytokines (IL-17A and IL-17F) in severe asthma

(2009) Wisam Al-Ramli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma

(2008) P Bhavsar et al.   THORAX