Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner

HIV-1 uncoats in the nucleus near sites of integration

(2020) Ryan C. Burdick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core

(2020) Anastasia Selyutina et al.   Cell Reports

TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

(2020) Molly Ohainle et al.   PLoS Pathogens

DAXX in cancer: phenomena, processes, mechanisms and regulation

(2019) Iqbal Mahmud et al.   NUCLEIC ACIDS RESEARCH

Interplay between Intrinsic and Innate Immunity during HIV Infection

(2019) Louis Bergantz et al.   Cells

Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating

(2019) Juliette Fernandez et al.   Nature Microbiology

Cyclophilin A protects HIV-1 from restriction by human TRIM5α

(2019) Kyusik Kim et al.   Nature Microbiology

Novel host restriction factors implicated in HIV-1 replication

(2018) Dibya Ghimire et al.   JOURNAL OF GENERAL VIROLOGY

Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1

(2018) Marta Colomer-Lluch et al.   Frontiers in Immunology

Interferons and beyond: Induction of antiretroviral restriction factors

(2017) Dominik Hotter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reverse Transcription Mechanically Initiates HIV-1 Capsid Disassembly

(2017) Sanela Rankovic et al.   JOURNAL OF VIROLOGY

Capsid-Dependent Host Factors in HIV-1 Infection

(2017) Masahiro Yamashita et al.   TRENDS IN MICROBIOLOGY

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape

(2015) Viviana Simon et al.   NATURE IMMUNOLOGY

TRIM5α is a SUMO substrate

(2015) Jacques Dutrieux et al.   Retrovirology

DAXX modulates human papillomavirus early gene expression and genome replication in U2OS cells

(2015) Piia Kivipõld et al.   Virology Journal

PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx

(2015) Jacques Dutrieux et al.   PLoS Pathogens

Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA

(2014) Alberto De Iaco et al.   Retrovirology

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

(2014) Zandrea Ambrose et al.   VIROLOGY

A model for cofactor use during HIV-1 reverse transcription and nuclear entry

(2014) Laura Hilditch et al.   Current Opinion in Virology

Virion Factors That Target Daxx To Overcome Intrinsic Immunity

(2013) S. Schreiner et al.   JOURNAL OF VIROLOGY

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm

(2013) Alberto De Iaco et al.   Retrovirology

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

(2013) Francesca Di Nunzio et al.   VIROLOGY

Inhibition of Reverse Transcriptase Activity Increases Stability of the HIV-1 Core

(2012) Y. Yang et al.   JOURNAL OF VIROLOGY

Retroviral DNA Methylation and Epigenetic Repression Are Mediated by the Antiviral Host Protein Daxx

(2012) N. Shalginskikh et al.   JOURNAL OF VIROLOGY

TNPO3 Is Required for HIV-1 Replication after Nuclear Import but prior to Integration and Binds the HIV-1 Core

(2012) J. C. Valle-Casuso et al.   JOURNAL OF VIROLOGY

The Host Proteins Transportin SR2/TNPO3 and Cyclophilin A Exert Opposing Effects on HIV-1 Uncoating

(2012) V. B. Shah et al.   JOURNAL OF VIROLOGY

DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition

(2012) Simon J. Elsässer et al.   NATURE

Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration

(2012) Francesca Di Nunzio et al.   PLoS One

Multiple roles of the capsid protein in the early steps of HIV-1 infection

(2012) Ariberto Fassati   VIRUS RESEARCH

Impairment of Human Immunodeficiency Virus Type-1 Integrase SUMOylation Correlates with an Early Replication Defect

(2011) Alessia Zamborlini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription

(2011) A. E. Hulme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SUMO-Interacting Motifs of Human TRIM5α are Important for Antiviral Activity

(2011) Gloria Arriagada et al.   PLoS Pathogens

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Uncoating of Human Immunodeficiency Virus Type 1 Requires Prolyl Isomerase Pin1

(2010) Shogo Misumi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Alpha Interferon-Induced Postentry Block to HIV-1 Infection in Primary Human Macrophages and T Cells

(2010) C. Goujon et al.   JOURNAL OF VIROLOGY

Target Cell Type-Dependent Modulation of Human Immunodeficiency Virus Type 1 Capsid Disassembly by Cyclophilin A

(2009) Y. Li et al.   JOURNAL OF VIROLOGY

Daxx interacts with HIV-1 integrase and inhibits lentiviral gene expression

(2008) Lu Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cyclophilin A Levels Dictate Infection Efficiency of Human Immunodeficiency Virus Type 1 Capsid Escape Mutants A92E and G94D

(2008) L. M. J. Ylinen et al.   JOURNAL OF VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

No effect of endogenous TRIM5α on HIV-1 production

(2008) Fengwen Zhang et al.   NATURE MEDICINE

Implication of TRIMalpha and TRIMCyp in interferon-induced anti-retroviral restriction activities

(2008) Laetitia Carthagena et al.   Retrovirology