Novel host restriction factors implicated in HIV-1 replication

The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles

(2017) Birthe Trautz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins

(2017) Chetan Sood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction

(2017) Xianfeng Zhang et al.   JOURNAL OF VIROLOGY

CG dinucleotide suppression enables antiviral defence targeting non-self RNA

(2017) Matthew A. Takata et al.   NATURE

TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)

(2017) Melody M. H. Li et al.   PLoS Pathogens

Functional organization of human SAMHD1 and mechanisms of HIV-1 restriction

(2016) Jinwoo Ahn   BIOLOGICAL CHEMISTRY

Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity

(2016) Christian Krapp et al.   Cell Host & Microbe

Effect of HIV-1 Env on SERINC5 Antagonism

(2016) Saina Beitari et al.   JOURNAL OF VIROLOGY

N-Glycan-based ER Molecular Chaperone and Protein Quality Control System: The Calnexin Binding Cycle

(2016) Lydia Lamriben et al.   TRAFFIC

Five Questions (with their Answers) on ER-Associated Degradation

(2016) Giorgia Brambilla Pisoni et al.   TRAFFIC

Status of vaccine research and development of vaccines for HIV-1

(2016) Jeffrey T. Safrit et al.   VACCINE

HIV-1 Vpr increases Env expression by preventing Env from endoplasmic reticulum-associated protein degradation (ERAD)

(2016) Xianfeng Zhang et al.   VIROLOGY

Identification of an HIV-1 replication inhibitor which rescues host restriction factor APOBEC3G in Vif–APOBEC3G complex

(2015) Shaoyang Zhang et al.   ANTIVIRAL RESEARCH

The innate immune roles of host factors TRIM5α and Cyclophilin A on HIV-1 replication

(2015) Yi-Qun Kuang et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

(2015) Yoshiko Usami et al.   NATURE

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

(2015) Annachiara Rosa et al.   NATURE

Nuclear matrix protein Matrin 3 is a regulator of ZAP-mediated retroviral restriction

(2015) Angela Erazo et al.   Retrovirology

Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses

(2015) Paul J McLaren et al.   Retrovirology

N-linked sugar-regulated protein folding and quality control in the ER

(2015) Abla Tannous et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

HIV-1 Replication and the Cellular Eukaryotic Translation Apparatus

(2015) Santiago Guerrero et al.   Viruses-Basel

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

(2015) John L. Goodier et al.   PLoS Genetics

Vpr Overcomes Macrophage-Specific Restriction of HIV-1 Env Expression and Virion Production

(2014) Michael Mashiba et al.   Cell Host & Microbe

The Mitochondrial Translocator Protein, TSPO, Inhibits HIV-1 Envelope Glycoprotein Biosynthesis via the Endoplasmic Reticulum-Associated Protein Degradation Pathway

(2014) T. Zhou et al.   JOURNAL OF VIROLOGY

The Nef-Like Effect of Murine Leukemia Virus Glycosylated Gag on HIV-1 Infectivity Is Mediated by Its Cytoplasmic Domain and Depends on the AP-2 Adaptor Complex

(2014) Y. Usami et al.   JOURNAL OF VIROLOGY

GuavaH: a compendium of host genomic data in HIV biology and disease

(2014) István Bartha et al.   Retrovirology

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

CBFβ Stabilizes HIV Vif to Counteract APOBEC3 at the Expense of RUNX1 Target Gene Expression

(2013) Dong Young Kim et al.   MOLECULAR CELL

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

(2013) T. P. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression profile of host restriction factors in HIV-1 elite controllers

(2013) Mohamed Abdel-Mohsen et al.   Retrovirology

Inhibition of Hepatitis B Virus Replication by the Host Zinc Finger Antiviral Protein

(2013) Richeng Mao et al.   PLoS Pathogens

Translational repression precedes and is required for ZAP-mediated mRNA decay

(2012) Yiping Zhu et al.   EMBO JOURNAL

Tight Interplay among SAMHD1 Protein Level, Cellular dNTP Levels, and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-derived Macrophages

(2012) Baek Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZAP Inhibits Murine Gammaherpesvirus 68 ORF64 Expression and Is Antagonized by RTA

(2012) Y. Xuan et al.   JOURNAL OF VIROLOGY

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA

(2012) Shoudeng Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Zinc-Finger Antiviral Protein Inhibits XMRV Infection

(2012) Xinlu Wang et al.   PLoS One

One Protein to Rule them All: Modulation of Cell Surface Receptors and Molecules by HIV Nef

(2011) Alessia Landi et al.   CURRENT HIV RESEARCH

Statistical Interpretation of the RV144 HIV Vaccine Efficacy Trial in Thailand: A Case Study for Statistical Issues in Efficacy Trials

(2011) P. B. Gilbert et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation

(2011) Mary Ann Checkley et al.   JOURNAL OF MOLECULAR BIOLOGY

Prevention of HIV-1 Infection with Early Antiretroviral Therapy

(2011) Myron S. Cohen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Matrin 3 Binds and Stabilizes mRNA

(2011) Maayan Salton et al.   PLoS One

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

(2011) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function

(2011) Anna Kula et al.   Retrovirology

Matrin 3 is a co-factor for HIV-1 Rev in regulating post-transcriptional viral gene expression

(2011) Venkat SRK Yedavalli et al.   Retrovirology

Functions and regulation of the APOBEC family of proteins

(2011) Harold C. Smith et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Disulfide bonds in ER protein folding and homeostasis

(2010) Matthias J Feige et al.   CURRENT OPINION IN CELL BIOLOGY

ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology

(2010) B. Kornmann et al.   JOURNAL OF CELL SCIENCE

The Guanylate-Binding Proteins: Emerging Insights into the Biochemical Properties and Functions of This Family of Large Interferon-Induced Guanosine Triphosphatase

(2010) Deborah J. Vestal et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Identification of a Dominant Negative Inhibitor of Human Zinc Finger Antiviral Protein Reveals a Functional Endogenous Pool and Critical Homotypic Interactions

(2010) L. M. J. Law et al.   JOURNAL OF VIROLOGY

The Alphaherpesvirus US3/ORF66 Protein Kinases Direct Phosphorylation of the Nuclear Matrix Protein Matrin 3

(2010) A. Erazo et al.   JOURNAL OF VIROLOGY

MLV glycosylated-Gag is an infectivity factor that rescues Nef-deficient HIV-1

(2010) M. Pizzato   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

(2009) Yasuhiro Itsui et al.   HEPATOLOGY

A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR

(2009) Tao Zhou et al.   Retrovirology

Multiple ways of targeting APOBEC3–virion infectivity factor interactions for anti-HIV-1 drug development

(2009) Jessica L. Smith et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

(2009) Matthew W. McNatt et al.   PLoS Pathogens

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

(2008) Kuan-Ming Chen et al.   NATURE

APOBEC proteins and intrinsic resistance to HIV-1 infection

(2008) M. H Malim   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

(2008) Julie A. Kerns et al.   PLoS Genetics

Demonstration of a Novel HIV-1 Restriction Phenotype from a Human T Cell Line

(2008) Yanxing Han et al.   PLoS One

HIV-1 Vif, APOBEC, and Intrinsic Immunity

(2008) Ritu Goila-Gaur et al.   Retrovirology

Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated Degradation

(2007) Edward Avezov et al.   MOLECULAR BIOLOGY OF THE CELL