Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

The relationship between autophagy, increased neutrophil extracellular traps formation and endothelial dysfunction in chronic kidney disease

(2018) Jwa-Kyung Kim et al.   CLINICAL IMMUNOLOGY

IL-17 Receptor Signaling Negatively Regulates the Development of Tubulointerstitial Fibrosis in the Kidney

(2018) Kritika Ramani et al.   MEDIATORS OF INFLAMMATION

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

(2017) Laurent L. Reber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

(2017) Giang T. Nguyen et al.   Frontiers in Cellular and Infection Microbiology

Reactive Oxygen Species and Neutrophil Function

(2016) Christine C. Winterbourn et al.   Annual Review of Biochemistry

Epidemiology and Mechanisms of Uremia-Related Cardiovascular Disease

(2016) Marcello Tonelli et al.   CIRCULATION

FGF23 signaling impairs neutrophil recruitment and host defense during CKD

(2016) Jan Rossaint et al.   JOURNAL OF CLINICAL INVESTIGATION

A Metabolic Shift toward Pentose Phosphate Pathway Is Necessary for Amyloid Fibril- and Phorbol 12-Myristate 13-Acetate-induced Neutrophil Extracellular Trap (NET) Formation

(2015) Estefania P. Azevedo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophils and inflammatory metabolism in antimicrobial functions of the mucosa

(2015) E. L. Campbell et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A Protein Kinase C Phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency Syndrome

(2015) Eunice E. Lee et al.   MOLECULAR CELL

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

Prophylactic vaccinations in chronic kidney disease: Current status

(2015) Alicja E Grzegorzewska   Human Vaccines & Immunotherapeutics

Neuroprotective Effects of Lithium: Implications for the Treatment of Alzheimer’s Disease and Related Neurodegenerative Disorders

(2014) O. V. Forlenza et al.   ACS Chemical Neuroscience

Meta-Analysis of Methicillin-Resistant Staphylococcus aureus Colonization and Risk of Infection in Dialysis Patients

(2014) I. M. Zacharioudakis et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

New insights into innate immune control of systemic candidiasis

(2014) Michail S. Lionakis   MEDICAL MYCOLOGY

Mechanisms Underlying the Exquisite Sensitivity of Candida albicans to Combinatorial Cationic and Oxidative Stress That Enhances the Potent Fungicidal Activity of Phagocytes

(2014) D. Kaloriti et al.   mBio

Epidemiology and risk factors for invasive candidiasis

(2014) Nur Yapar   Therapeutics and Clinical Risk Management

Metabolic Regulation of T Lymphocytes

(2013) Nancie J. MacIver et al.   Annual Review of Immunology

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Increased reactive oxygen species production and p47phox phosphorylation in neutrophils from myeloproliferative disorders patients with JAK2 (V617F) mutation

(2013) M. Hurtado-Nedelec et al.   HAEMATOLOGICA

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

The Uremic Toxin Indoxyl Sulphate Enhances Macrophage Response to LPS

(2013) Simona Adesso et al.   PLoS One

NADPH Oxidase-Driven Phagocyte Recruitment Controls Candida albicans Filamentous Growth and Prevents Mortality

(2013) Kimberly M. Brothers et al.   PLoS Pathogens

Regulation of Glucose Transporter Translocation in Health and Diabetes

(2012) Jonathan S. Bogan   Annual Review of Biochemistry

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Searching for Uremic Toxins

(2012) M. Dobre et al.   Clinical Journal of the American Society of Nephrology

Probenecid prevents acute tubular necrosis in a mouse model of aristolochic acid nephropathy

(2012) Thomas E.R. Baudoux et al.   KIDNEY INTERNATIONAL

A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo

(2012) Y. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Urea Amidolyase (DUR1,2) Contributes to Virulence and Kidney Pathogenesis of Candida albicans

(2012) Dhammika H. M. L. P. Navarathna et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Inhibition of GSK3 by lithium, from single molecules to signaling networks

(2012) Laure Freland et al.   Frontiers in Molecular Neuroscience

Chronic Kidney Disease and Risk of Death from Infection

(2011) Henry E. Wang et al.   AMERICAN JOURNAL OF NEPHROLOGY

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

Insights from human studies into the host defense against candidiasis

(2011) Scott G. Filler   CYTOKINE

Epithelial Phosphatidylinositol-3-Kinase Signaling Is Required for β-Catenin Activation and Host Defense against Citrobacter rodentium Infection

(2011) Jeffrey B. Brown et al.   INFECTION AND IMMUNITY

Effect of Uremia on Structure and Function of Immune System

(2011) Nosratola D. Vaziri et al.   JOURNAL OF RENAL NUTRITION

Acute loss of renal function attenuates slow leukocyte rolling and transmigration by interfering with intracellular signaling

(2011) Jan Rossaint et al.   KIDNEY INTERNATIONAL

Critical Role of Organic Anion Transporters 1 and 3 in Kidney Accumulation and Toxicity of Aristolochic Acid I

(2011) Xiang Xue et al.   MOLECULAR PHARMACEUTICS

Uremia induces functional incompetence of bone marrow-derived stromal cells

(2011) Hyunjin Noh et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

(2010) Qingsong Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Glucose transporters in the 21st Century

(2009) Bernard Thorens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Clinical Outcomes of Dialysis Catheter-Related Candidemia in Hemodialysis Patients

(2009) D. Sychev et al.   Clinical Journal of the American Society of Nephrology

Epidemiology of Acute Infections among Patients with Chronic Kidney Disease

(2008) L. S. Dalrymple et al.   Clinical Journal of the American Society of Nephrology

Aristolochic acid nephropathy: A worldwide problem

(2008) Frédéric D. Debelle et al.   KIDNEY INTERNATIONAL

Candida bloodstream infections in hemodialysis recipients

(2008) Vasilios Pyrgos et al.   MEDICAL MYCOLOGY