Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition

Anti-inflammatory Effects of Traditional Chinese Medicines on Preclinical in vivo Models of Brain Ischemia-Reperfusion-Injury: Prospects for Neuroprotective Drug Discovery and Therapy

(2019) Tangming Peng et al.   Frontiers in Pharmacology

Rab7b Overexpression–Ameliorated Ischemic Brain Damage Following tMCAO Involves Suppression of TLR4 and NF-κB p65

(2019) Jinlong Qi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury

(2019) Lin Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Toll-like receptor 4 regulates subventricular zone proliferation and neuroblast migration after experimental stroke

(2019) Sara Palma-Tortosa et al.   BRAIN BEHAVIOR AND IMMUNITY

Early TLR4 blockade reduces ROS and inflammation triggered by microglial pro‐inflammatory phenotype in rodents and human brain ischemia models

(2019) E. Parada et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroprotective effects of neurotropin in a mouse model of hypoxic–ischemic brain injury

(2019) Sohei Hishiyama et al.   Journal of Anesthesia

Thrombolysis in young adults with stroke

(2019) Jodi A. Dodds et al.   NEUROLOGY

Interleukin-11 treatment protected against cerebral ischemia/reperfusion injury

(2019) Bei Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Blood microRNA-15a Correlates with IL-6, IGF-1 and Acute Cerebral Ischemia

(2018) Wen-Jing Lu et al.   CURRENT NEUROVASCULAR RESEARCH

The Immune System and Stroke: From Current Targets to Future Therapy

(2018) Kyle Malone et al.   IMMUNOLOGY AND CELL BIOLOGY

Lentivirus-mediated overexpression of OTULIN ameliorates microglia activation and neuroinflammation by depressing the activation of the NF-κB signaling pathway in cerebral ischemia/reperfusion rats

(2018) Hongbei Xu et al.   Journal of Neuroinflammation

Angioedema and Hemorrhage After 4.5-Hour tPA (Tissue-Type Plasminogen Activator) Thrombolysis Ameliorated by T541 via Restoring Brain Microvascular Integrity

(2018) Qing-Fang Chen et al.   STROKE

Schisandrin B alleviates diabetic nephropathy through suppressing excessive inflammation and oxidative stress

(2018) Zhenxin Mou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Schisandrin B Attenuates Inflammation in LPS-Induced Sepsis Through miR-17-5p Downregulating TLR4

(2018) Zhi-Rong Ji et al.   INFLAMMATION

Schisandrin B Improves the Renal Function of IgA Nephropathy Rats Through Inhibition of the NF-κB Signalling Pathway

(2018) Jian-Hua Qin et al.   INFLAMMATION

Schisandrin B Ameliorates Myocardial Ischemia/Reperfusion Injury Through Attenuation of Endoplasmic Reticulum Stress-Induced Apoptosis

(2017) Wei Zhang et al.   INFLAMMATION

Ulinastatin downregulates TLR4 and NF-kB expression and protects mouse brains against ischemia/reperfusion injury

(2017) Xiaofang Li et al.   NEUROLOGICAL RESEARCH

Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift

(2017) Yasir N. Jassam et al.   NEURON

Schisandrin B Prevents Hind Limb from Ischemia-Reperfusion-Induced Oxidative Stress and Inflammation via MAPK/NF-κB Pathways in Rats

(2017) Ning Zhu et al.   Biomed Research International

Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats

(2016) Cai-Ping Wang et al.   MOLECULAR NEUROBIOLOGY

Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies

(2016) Stavroula Ntoufa et al.   SEMINARS IN CANCER BIOLOGY

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

(2014) Jonathan Emberson et al.   LANCET

TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion

(2013) Ying Wang et al.   MEDIATORS OF INFLAMMATION

Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide-induced microglia

(2012) Ke-Wu Zeng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective effects of Schisandrin B against transient focal cerebral ischemia in Sprague–Dawley rats

(2012) Tae Hwa Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

TLR2 and TLR4 in Ischemia Reperfusion Injury

(2010) F. Arslan et al.   MEDIATORS OF INFLAMMATION

Schisandrin B Enhances Cerebral Mitochondrial Antioxidant Status and Structural Integrity, and Protects against Cerebral Ischemia/Reperfusion Injury in Rats

(2008) Na Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN