Synapse development and maturation at the drosophila neuromuscular junction

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells

(2020) Elizabeth M. McNeill et al.   Nature Communications

Drosophila enabled promotes synapse morphogenesis and regulates active zone form and function

(2020) Elizabeth M. McNeill et al.   Neural Development

Homeostatic scaling of active zone scaffolds maintains global synaptic strength

(2019) Pragya Goel et al.   JOURNAL OF CELL BIOLOGY

Nanomachinery Organizing Release at Neuronal and Ribbon Synapses

(2019) Chakrabarti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Commissural axon guidance in the developing spinal cord: from Cajal to the present day

(2019) J. D. Comer et al.   Neural Development

The HSPG Glypican Regulates Experience-Dependent Synaptic and Behavioral Plasticity by Modulating the Non-Canonical BMP Pathway

(2019) Keisuke Kamimura et al.   Cell Reports

A Student’s Guide to Neural Circuit Tracing

(2019) Christine Saleeba et al.   Frontiers in Neuroscience

The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway

(2019) Kendall M. Hoover et al.   Nature Communications

PAKs in the brain: Function and dysfunction

(2018) Laura Civiero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Functional organization of postsynaptic glutamate receptors

(2018) Nicky Scheefhals et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Drosophila active zones: From molecules to behaviour

(2018) Nadine Ehmann et al.   NEUROSCIENCE RESEARCH

Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior

(2018) Julia Brasch et al.   Cell Reports

ELKS active zone proteins as multitasking scaffolds for secretion

(2018) Richard G. Held et al.   Open Biology

Neurexin–Neuroligin 1 regulates synaptic morphology and functions via the WAVE regulatory complex in Drosophila neuromuscular junction

(2018) Guanglin Xing et al.   eLife

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles

(2018) Anela Vukoja et al.   NEURON

Rapid Assembly of Presynaptic Materials behind the Growth Cone in Dopaminergic Neurons Is Mediated by Precise Regulation of Axonal Transport

(2018) David M. Lipton et al.   Cell Reports

Towards an Understanding of Synapse Formation

(2018) Thomas C. Südhof   NEURON

DrosophilaSyd-1 Has RhoGAP Activity That Is Required for Presynaptic Clustering of Bruchpilot/ELKS but Not Neurexin-1

(2017) Michael A. Spinner et al.   GENETICS

Neurexin, Neuroligin and Wishful Thinking coordinate synaptic cytoarchitecture and growth at neuromuscular junctions

(2017) Swati Banerjee et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Unc13 Aligns SNAREs and Superprimes Synaptic Vesicles

(2017) Mark T. Palfreyman et al.   NEURON

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18

(2017) Ying Lai et al.   NEURON

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins

(2017) Lulu Y. Chen et al.   NEURON

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN

(2017) Junjie Xu et al.   eLife

DrosophilaSyd-1 Has RhoGAP Activity That Is Required for Presynaptic Clustering of Bruchpilot/ELKS but Not Neurexin-1

(2017) Michael A. Spinner et al.   GENETICS

Mechanisms controlling assembly and plasticity of presynaptic active zone scaffolds

(2016) Astrid G Petzoldt et al.   CURRENT OPINION IN NEUROBIOLOGY

Cytoskeletal social networking in the growth cone: How +TIPs mediate microtubule-actin cross-linking to drive axon outgrowth and guidance

(2016) Garrett M. Cammarata et al.   Cytoskeleton

Dpr-DIP matching expression in Drosophila synaptic pairs

(2016) Marta Morey   FLY

Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling

(2016) Mathias A Böhme et al.   NATURE NEUROSCIENCE

Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca2+ Channels

(2016) César Astorga et al.   Scientific Reports

C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction

(2016) Ashlyn M. Spring et al.   PLoS Genetics

A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction

(2016) Mikolaj J. Sulkowski et al.   PLoS Genetics

Maturation of active zone assembly byDrosophilaBruchpilot

(2016) Wernher Fouquet et al.   JOURNAL OF CELL BIOLOGY

Two classes of matrix metalloproteinases reciprocally regulate synaptogenesis

(2015) Mary Lynn Dear et al.   DEVELOPMENT

Presynaptic active zones in invertebrates and vertebrates

(2015) F. Ackermann et al.   EMBO REPORTS

RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse

(2015) Yunyun Han et al.   JOURNAL OF NEUROPHYSIOLOGY

Molecular Remodeling of the Presynaptic Active Zone of Drosophila Photoreceptors via Activity-Dependent Feedback

(2015) Atsushi Sugie et al.   NEURON

Functional reconstitution ofDrosophila melanogasterNMJ glutamate receptors

(2015) Tae Hee Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the Teneurin track: a new synaptic organization molecule emerges

(2015) Timothy J. Mosca   Frontiers in Cellular Neuroscience

Structural Components of Synaptic Plasticity and Memory Consolidation

(2015) Craig H. Bailey et al.   Cold Spring Harbor Perspectives in Biology

The classic cadherins in synaptic specificity

(2015) Raunak Basu et al.   Cell Adhesion & Migration

Cadherins and catenins in dendrite and synapse morphogenesis

(2015) Eunju Seong et al.   Cell Adhesion & Migration

Neto-Mediated Intracellular Interactions Shape Postsynaptic Composition at the Drosophila Neuromuscular Junction

(2015) Cathy I. Ramos et al.   PLoS Genetics

Axon and dendritic trafficking

(2014) Celine I Maeder et al.   CURRENT OPINION IN NEUROBIOLOGY

miR-8 controls synapse structure by repression of the actin regulator Enabled

(2014) Carlos M. Loya et al.   DEVELOPMENT

Crimpy Enables Discrimination of Presynaptic and Postsynaptic Pools of a BMP at the Drosophila Neuromuscular Junction

(2014) Rebecca E. James et al.   DEVELOPMENTAL CELL

The SynCAM synaptic cell adhesion molecules are involved in sensory axon pathfinding by regulating axon-axon contacts

(2014) J. A. Frei et al.   JOURNAL OF CELL SCIENCE

Dscam1 Is Required for Normal Dendrite Growth and Branching But Not for Dendritic Spacing in Drosophila Motoneurons

(2014) K. M. Hutchinson et al.   JOURNAL OF NEUROSCIENCE

Drosophila Syd-1, Liprin- , and Protein Phosphatase 2A B' Subunit Wrd Function in a Linear Pathway to Prevent Ectopic Accumulation of Synaptic Materials in Distal Axons

(2014) L. Li et al.   JOURNAL OF NEUROSCIENCE

Synapsin Regulates Activity-Dependent Outgrowth of Synaptic Boutons at the Drosophila Neuromuscular Junction

(2014) A. Vasin et al.   JOURNAL OF NEUROSCIENCE

Retrograde BMP Signaling Modulates Rapid Activity-Dependent Synaptic Growth via Presynaptic LIM Kinase Regulation of Cofilin

(2014) Z. D. Piccioli et al.   JOURNAL OF NEUROSCIENCE

The teneurins: New players in the generation of visual topography

(2014) Catherine A. Leamey et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states

(2014) Nadine Ehmann et al.   Nature Communications

Phospho-regulated Drosophila adducin is a determinant of synaptic plasticity in a complex with Dlg and PIP2 at the larval neuromuscular junction

(2014) S. J. H. Wang et al.   Biology Open

Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila

(2013) S. H. Friedman et al.   Disease Models & Mechanisms

Ral mediates activity-dependent growth of postsynaptic membranes via recruitment of the exocyst

(2013) Rita O Teodoro et al.   EMBO JOURNAL

Syndapin - a membrane remodelling and endocytic F-BAR protein

(2013) Annie Quan et al.   FEBS Journal

Functions and Mechanisms of Fibroblast Growth Factor (FGF) Signalling in Drosophila melanogaster

(2013) Villö Muha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles

(2013) Tanja Matkovic et al.   JOURNAL OF CELL BIOLOGY

Cellular and molecular mechanisms underlying presynapse formation

(2013) Poh Hui Chia et al.   JOURNAL OF CELL BIOLOGY

Perlecan regulates bidirectional Wnt signaling at theDrosophilaneuromuscular junction

(2013) Keisuke Kamimura et al.   JOURNAL OF CELL BIOLOGY

Retrograde BMP Signaling at the Synapse: A Permissive Signal for Synapse Maturation and Activity-Dependent Plasticity

(2013) B. Berke et al.   JOURNAL OF NEUROSCIENCE

mSYD1A, a Mammalian Synapse-Defective-1 Protein, Regulates Synaptogenic Signaling and Vesicle Docking

(2013) Corinna Wentzel et al.   NEURON

The Balance between Capture and Dissociation of Presynaptic Proteins Controls the Spatial Distribution of Synapses

(2013) Ye E. Wu et al.   NEURON

Cell adhesion and homeostatic synaptic plasticity

(2013) Agnes Thalhammer et al.   NEUROPHARMACOLOGY

The miRNA Pathway Controls Rapid Changes in Activity-Dependent Synaptic Structure at the Drosophila melanogaster Neuromuscular Junction

(2013) Katherine R. Nesler et al.   PLoS One

LAR-RPTPs: synaptic adhesion molecules that shape synapse development

(2013) Ji Won Um et al.   TRENDS IN CELL BIOLOGY

Development of larval motor circuits in Drosophila

(2012) Hiroshi Kohsaka et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Structure-function analysis of endogenous lectin mind-the-gap in synaptogenesis

(2012) Emma Rushton et al.   Developmental Neurobiology

Jelly bellytrans-synaptic signaling to anaplastic lymphoma kinase regulates neurotransmission strength and synapse architecture

(2012) Jeffrey Rohrbough et al.   Developmental Neurobiology

Drosophila Neto is essential for clustering glutamate receptors at the neuromuscular junction

(2012) Y.-J. Kim et al.   GENES & DEVELOPMENT

RIM Promotes Calcium Channel Accumulation at Active Zones of the Drosophila Neuromuscular Junction

(2012) E. R. Graf et al.   JOURNAL OF NEUROSCIENCE

Drosophila Neuroligin 2 is Required Presynaptically and Postsynaptically for Proper Synaptic Differentiation and Synaptic Transmission

(2012) Y.-C. Chen et al.   JOURNAL OF NEUROSCIENCE

Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice

(2012) Timothy J. Mosca et al.   NATURE

Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly

(2012) David Owald et al.   NATURE NEUROSCIENCE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Cadherins in Brain Morphogenesis and Wiring

(2012) Shinji Hirano et al.   PHYSIOLOGICAL REVIEWS

Cell adhesion molecules in Drosophila synapse development and function

(2012) MingKuan Sun et al.   Science China-Life Sciences

Wnt Signaling in Neuromuscular Junction Development

(2012) K. Koles et al.   Cold Spring Harbor Perspectives in Biology

RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction

(2011) Pascal S. Kaeser et al.   CELL

Neurexins and neuroligins: synapses look out of the nervous system

(2011) Alessia Bottos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cadherin-catenin adhesion complexes at the synapse

(2011) G Stefano Brigidi et al.   CURRENT OPINION IN NEUROBIOLOGY

Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane

(2011) Simon Wang et al.   DEVELOPMENTAL BIOLOGY

Glycosylated synaptomatrix regulation of trans-synaptic signaling

(2011) Neil Dani et al.   Developmental Neurobiology

Barfly: Sculpting membranes at the Drosophila neuromuscular junction

(2011) Eugene Oh et al.   Developmental Neurobiology

Eph/ephrin signaling in cell-cell and cell-substrate adhesion

(2011) Arvinder Singh   Frontiers in Bioscience-Landmark

Modeling spinal muscular atrophy inDrosophilalinksSmnto FGF signaling

(2011) Anindya Sen et al.   JOURNAL OF CELL BIOLOGY

The Presynaptic Dense Projection of the Caenorhabiditis elegans Cholinergic Neuromuscular Junction Localizes Synaptic Vesicles at the Active Zone through SYD-2/Liprin and UNC-10/RIM-Dependent Interactions

(2011) C. Stigloher et al.   JOURNAL OF NEUROSCIENCE

Neurexins and Neuroligins: Recent Insights from Invertebrates

(2011) David Knight et al.   MOLECULAR NEUROBIOLOGY

Differential control of presynaptic efficacy by postsynaptic N-cadherin and β-catenin

(2011) Nathalia Vitureira et al.   NATURE NEUROSCIENCE

Meningeal cells and glia establish a permissive environment for axon regeneration after spinal cord injury in newts

(2011) Katherine A Zukor et al.   Neural Development

Hts/Adducin Controls Synaptic Elaboration and Elimination

(2011) Jan Pielage et al.   NEURON

RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13

(2011) Lunbin Deng et al.   NEURON

Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

(2011) U. B. Pandey et al.   PHARMACOLOGICAL REVIEWS

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

(2011) Zdravko Petanjek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release

(2011) K. S. Y. Liu et al.   SCIENCE

The Postsynaptic Organization of Synapses

(2011) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

RIM proteins and their role in synapse function

(2010) Tobias Mittelstaedt et al.   BIOLOGICAL CHEMISTRY

Single-Cell Adhesion Tests against Functionalized Microspheres Arrayed on AFM Cantilevers Confirm Heterophilic E- and N-Cadherin Binding

(2010) Chawin Ounkomol et al.   BIOPHYSICAL JOURNAL

The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases

(2010) Vafa Bayat et al.   CURRENT OPINION IN NEUROBIOLOGY

Anterograde Jelly belly ligand to Alk receptor signaling at developing synapses is regulated by Mind the gap

(2010) J. Rohrbough et al.   DEVELOPMENT

Cadherins in neuronal morphogenesis and function

(2010) Sachihiro C. Suzuki et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

N-cadherin mediates plasticity-induced long-term spine stabilization

(2010) Pablo Mendez et al.   JOURNAL OF CELL BIOLOGY

A Syd-1 homologue regulates pre- and postsynaptic maturation inDrosophila

(2010) David Owald et al.   JOURNAL OF CELL BIOLOGY

Three Drosophila Liprins Interact to Control Synapse Formation

(2010) S. Astigarraga et al.   JOURNAL OF NEUROSCIENCE

Persistence of Coordinated Long-Term Potentiation and Dendritic Spine Enlargement at Mature Hippocampal CA1 Synapses Requires N-Cadherin

(2010) O. Bozdagi et al.   JOURNAL OF NEUROSCIENCE

Two pools of vesicles associated with the presynaptic cytosolic projection in Drosophila neuromuscular junctions

(2010) Wei Jiao et al.   JOURNAL OF STRUCTURAL BIOLOGY

Retrograde BMP Signaling Controls Synaptic Growth at the NMJ by Regulating Trio Expression in Motor Neurons

(2010) Robin W. Ball et al.   NEURON

Drosophila Neuroligin 1 Promotes Growth and Postsynaptic Differentiation at Glutamatergic Neuromuscular Junctions

(2010) Daniel Banovic et al.   NEURON

Neurexin in Embryonic Drosophila Neuromuscular Junctions

(2010) Kaiyun Chen et al.   PLoS One

CNTNAP2 and NRXN1 Are Mutated in Autosomal-Recessive Pitt-Hopkins-like Mental Retardation and Determine the Level of a Common Synaptic Protein in Drosophila

(2009) Christiane Zweier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

(2009) Kwok-On Lai et al.   CURRENT OPINION IN NEUROBIOLOGY

Abi plays an opposing role to Abl in Drosophila axonogenesis and synaptogenesis

(2009) T.-Y. Lin et al.   DEVELOPMENT

Presynaptic secretion of mind-the-gap organizes the synaptic extracellular matrix-integrin interface and postsynaptic environments

(2009) Emma Rushton et al.   DEVELOPMENTAL DYNAMICS

The human brain in numbers: a linearly scaled-up primate brain

(2009) Suzana Herculano-Houzel   Frontiers in Human Neuroscience

Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains

(2009) Cynthia F. Barber et al.   JOURNAL OF CELL BIOLOGY

Endodomain Diversity in the Drosophila Dscam and Its Roles in Neuronal Morphogenesis

(2009) H.-H. Yu et al.   JOURNAL OF NEUROSCIENCE

Syndapin Promotes Formation of a Postsynaptic Membrane System in Drosophila

(2009) Vimlesh Kumar et al.   MOLECULAR BIOLOGY OF THE CELL

The trip of the tip: understanding the growth cone machinery

(2009) Laura Anne Lowery et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Transmembrane Accessory Subunit that Modulates Kainate-Type Glutamate Receptors

(2009) Wei Zhang et al.   NEURON

Mouse neurexin-1  deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

(2009) M. R. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Adhesion, the Backbone of the Synapse: "Vertebrate" and "Invertebrate" Perspectives

(2009) N. Giagtzoglou et al.   Cold Spring Harbor Perspectives in Biology

Glia and Muscle Sculpt Neuromuscular Arbors by Engulfing Destabilized Synaptic Boutons and Shed Presynaptic Debris

(2009) Yuly Fuentes-Medel et al.   PLOS BIOLOGY

Molecular Mechanisms of Presynaptic Differentiation

(2008) Yishi Jin et al.   Annual Review of Cell and Developmental Biology

Axonal transport and the delivery of pre-synaptic components

(2008) Ann YN Goldstein et al.   CURRENT OPINION IN NEUROBIOLOGY

What is slow axonal transport?

(2008) Kyle E. Miller et al.   EXPERIMENTAL CELL RESEARCH

Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy

(2008) Shingo Kariya et al.   HUMAN MOLECULAR GENETICS

Presynaptic Local Signaling by a Canonical Wingless Pathway Regulates Development of the Drosophila Neuromuscular Junction

(2008) C. Miech et al.   JOURNAL OF NEUROSCIENCE

Formin-Dependent Synaptic Growth: Evidence That Dlar Signals via Diaphanous to Modulate Synaptic Actin and Dynamic Pioneer Microtubules

(2008) C. Pawson et al.   JOURNAL OF NEUROSCIENCE

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Activity-dependent site-specific changes of glutamate receptor composition in vivo

(2008) Andreas Schmid et al.   NATURE NEUROSCIENCE

Rapid Activity-Dependent Modifications in Synaptic Structure and Function Require Bidirectional Wnt Signaling

(2008) Bulent Ataman et al.   NEURON

Drosophila Ankyrin 2 Is Required for Synaptic Stability

(2008) Iris Koch et al.   NEURON

A Presynaptic Giant Ankyrin Stabilizes the NMJ through Regulation of Presynaptic Microtubules and Transsynaptic Cell Adhesion

(2008) Jan Pielage et al.   NEURON