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Title
Hypoxia in chronic kidney disease: towards a paradigm shift?
Authors
Keywords
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Journal
NEPHROLOGY DIALYSIS TRANSPLANTATION
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2020-04-05
DOI
10.1093/ndt/gfaa091
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Note: Only part of the references are listed.- Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice
- (2020) Mai Sugahara et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney
- (2019) Dong Ryeol Ryu et al. AGING CELL
- Oxidative stress and kidney function: a brief update
- (2019) Giuseppe Coppolino et al. CURRENT PHARMACEUTICAL DESIGN
- Hypoxia induces rapid changes to histone methylation and reprograms chromatin
- (2019) Michael Batie et al. SCIENCE
- Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
- (2019) Abhishek A. Chakraborty et al. SCIENCE
- Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis
- (2019) Gunnar Schley et al. KIDNEY INTERNATIONAL
- Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes
- (2019) Bianca Crifo et al. JOURNAL OF IMMUNOLOGY
- Roxadustat: First Global Approval
- (2019) Sohita Dhillon DRUGS
- Oxyphor 2P: A High-Performance Probe for Deep-Tissue Longitudinal Oxygen Imaging
- (2019) Tatiana V. Esipova et al. Cell Metabolism
- Oxidative Stress in the Pathogenesis and Evolution of Chronic Kidney Disease: Untangling Ariadne’s Thread
- (2019) Anila Duni et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis
- (2019) Nan Chen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis
- (2019) Nan Chen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1
- (2019) Christina Pickel et al. Redox Biology
- Now a Nobel gas: oxygen
- (2019) Joachim Fandrey et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Mechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose
- (2019) Coral García-Pastor et al. Scientific Reports
- HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity
- (2019) Pascale Sulser et al. FASEB JOURNAL
- DMOG, a Prolyl Hydroxylase Inhibitor, Increases Hemoglobin Levels without Exacerbating Hypertension and Renal Injury in Salt-Sensitive Hypertensive Rats
- (2019) Sota Kato et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat (FG-4592) protects against cisplatin-induced acute kidney injury
- (2018) Yunwen Yang et al. CLINICAL SCIENCE
- Source and microenvironmental regulation of erythropoietin in the kidney
- (2018) Karen A. Nolan et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Reduced cortical oxygenation predicts a progressive decline of renal function in patients with chronic kidney disease
- (2018) Menno Pruijm et al. KIDNEY INTERNATIONAL
- Effects of vadadustat on hemoglobin concentrations in patients receiving hemodialysis previously treated with erythropoiesis-stimulating agents
- (2018) Volker H Haase et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Renal Hypoxia: An Important Prognostic Marker in Patients with Chronic Kidney Disease
- (2018) Hua Zhou et al. AMERICAN JOURNAL OF NEPHROLOGY
- RNAi Silencing of HIF-1α Ameliorates Lupus Development in MRL/lpr Mice
- (2018) Wei Zhao et al. INFLAMMATION
- HIF-1α promotes cyst progression in a mouse model of autosomal dominant polycystic kidney disease
- (2018) Andre Kraus et al. KIDNEY INTERNATIONAL
- Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype
- (2018) Faik Imeri et al. KIDNEY INTERNATIONAL
- The functional interplay between the HIF pathway and the ubiquitin system – more than a one-way road
- (2017) Julia Günter et al. EXPERIMENTAL CELL RESEARCH
- Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice
- (2017) Shuo Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
- (2017) Tzu-Lan Yeh et al. Chemical Science
- Renal injury is accelerated by global hypoxia-inducible factor 1 alpha deficiency in a mouse model of STZ-induced diabetes
- (2017) Romana Bohuslavova et al. BMC Endocrine Disorders
- Renal Hypoxia in CKD; Pathophysiology and Detecting Methods
- (2017) Yosuke Hirakawa et al. Frontiers in Physiology
- Selective tubular activation of hypoxia-inducible factor-2α has dual effects on renal fibrosis
- (2017) Kyoung Hye Kong et al. Scientific Reports
- Zinc Attenuates Tubulointerstitial Fibrosis in Diabetic Nephropathy Via Inhibition of HIF Through PI-3K Signaling
- (2016) Xiuli Zhang et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice
- (2016) Bijaya K. Nayak et al. DIABETES
- Chronic intermittent hypobaric hypoxia ameliorates diabetic nephropathy through enhancing HIF1 signaling in rats
- (2016) Yan-Ming Tian et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Hypoxia-inducible factor-1α promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3
- (2016) Bethany Baumann et al. KIDNEY INTERNATIONAL
- Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
- (2016) Javier Rodriguez et al. Cell Reports
- Elevated Endothelial Hypoxia-Inducible Factor-1α Contributes to Glomerular Injury and Promotes Hypertensive Chronic Kidney DiseaseNovelty and Significance
- (2015) Renna Luo et al. HYPERTENSION
- Enhanced renoprotective effect of HIF-1α modified human adipose-derived stem cells on cisplatin-induced acute kidney injury in vivo
- (2015) Wei-Wei Wang et al. Scientific Reports
- Hypoxia Inducible Factor-1 Alpha Promotes Mesangial Cell Proliferation in Lupus Nephritis
- (2014) Wei Deng et al. AMERICAN JOURNAL OF NEPHROLOGY
- Determinants of renal tissue hypoxia in a rat model of polycystic kidney disease
- (2014) Connie P. C. Ow et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury
- (2014) Pinelopi P. Kapitsinou et al. JOURNAL OF CLINICAL INVESTIGATION
- Activation of Hypoxia-Inducible Factors Prevents Diabetic Nephropathy
- (2014) L. Nordquist et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Iron Chelation by Deferoxamine Prevents Renal Interstitial Fibrosis in Mice with Unilateral Ureteral Obstruction
- (2014) Yasumasa Ikeda et al. PLoS One
- Determinants of Renal Tissue Oxygenation as Measured with BOLD-MRI in Chronic Kidney Disease and Hypertension in Humans
- (2014) Menno Pruijm et al. PLoS One
- Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
- (2013) Gregg L. Semenza Annual Review of Pathology-Mechanisms of Disease
- Hydroxylase-dependent regulation of the NF-κB pathway
- (2013) Carsten C. Scholz et al. BIOLOGICAL CHEMISTRY
- Tubular von Hippel-Lindau Knockout Protects against Rhabdomyolysis-Induced AKI
- (2013) M. Fahling et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Medical Costs of CKD in the Medicare Population
- (2013) A. A. Honeycutt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Imaging local neuronal activity by monitoring PO2 transients in capillaries
- (2013) Alexandre Parpaleix et al. NATURE MEDICINE
- Regulation of IL-1 -induced NF- B by hydroxylases links key hypoxic and inflammatory signaling pathways
- (2013) C. C. Scholz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Myeloid Cell-Derived Hypoxia-Inducible Factor Attenuates Inflammation in Unilateral Ureteral Obstruction-Induced Kidney Injury
- (2012) H. Kobayashi et al. JOURNAL OF IMMUNOLOGY
- Renal BOLD-MRI does not reflect renal function in chronic kidney disease
- (2012) Henrik J. Michaely et al. KIDNEY INTERNATIONAL
- The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration
- (2012) Xiaofang Yu et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Renal Tubular HIF-2α Expression Requires VHL Inactivation and Causes Fibrosis and Cysts
- (2012) Ruth E. Schietke et al. PLoS One
- Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival
- (2012) Elisa Conde et al. PLoS One
- Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response
- (2011) Minna Heikkilä et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Silencing of Hypoxia-Inducible Factor-1α Gene Attenuated Angiotensin II–Induced Renal Injury in Sprague-Dawley Rats
- (2011) Qing Zhu et al. HYPERTENSION
- Transient hypoxia-inducible factor activation in rat renal ablation and reduced fibrosis with L-mimosine
- (2011) XIAOFANG YU et al. NEPHROLOGY
- The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment
- (2011) Z. Wang et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Hypoxia and Inflammation
- (2011) Holger K. Eltzschig et al. NEW ENGLAND JOURNAL OF MEDICINE
- Differential regulation of Snail by hypoxia and hyperglycemia in human proximal tubule cells
- (2010) Siska Sumual et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The suffocating kidney: tubulointerstitial hypoxia in end-stage renal disease
- (2010) Imari Mimura et al. Nature Reviews Nephrology
- Human Nephrosclerosis Triggers a Hypoxia-Related Glomerulopathy
- (2009) Matthias A. Neusser et al. AMERICAN JOURNAL OF PATHOLOGY
- Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney
- (2009) Y. R. Song et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Inhibition of Hypoxia Inducible Factor Hydroxylases Protects Against Renal Ischemia-Reperfusion Injury
- (2008) P. Hill et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics
- (2008) Leon G. Fine et al. KIDNEY INTERNATIONAL
- NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
- (2008) Jordi Rius et al. NATURE
- Mitochondria and cellular oxygen sensing in the HIF pathway
- (2007) Cormac T. Taylor BIOCHEMICAL JOURNAL
- Adaptation to hypoxia in the diabetic rat kidney
- (2007) C. Rosenberger et al. KIDNEY INTERNATIONAL
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