Oxidative Stress in the Pathogenesis and Evolution of Chronic Kidney Disease: Untangling Ariadne’s Thread

Canagliflozin, an SGLT2 inhibitor, normalizes renal susceptibility to type 1 cardiorenal syndrome through reduction of renal oxidative stress in diabetic rats

(2019) Yukishige Kimura et al.   Journal of Diabetes Investigation

Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies

(2019) Josef Coresh et al.   Lancet Diabetes & Endocrinology

Inflammation, Immunity, and Oxidative Stress in Hypertension—Partners in Crime?

(2019) Ian R. Barrows et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria

(2019) Lili Zhou et al.   KIDNEY INTERNATIONAL

Is oxidative stress an issue in peritoneal dialysis?

(2019) Stefanos Roumeliotis et al.   SEMINARS IN DIALYSIS

The association of OSR‐1 between vascular dysfunction and hypertension in polycystic kidney disease

(2019) Ismail Kocyigit et al.   THERAPEUTIC APHERESIS AND DIALYSIS

SerpinA3 in the Early Recognition of Acute Kidney Injury to Chronic Kidney Disease (CKD) transition in the rat and its Potentiality in the Recognition of Patients with CKD

(2019) Andrea Sánchez-Navarro et al.   Scientific Reports

Diabetic nephropathy: Is there a role for oxidative stress?

(2018) Manpreet K. Sagoo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The sirtuin1 gene associates with left ventricular myocardial hypertrophy and remodeling in two chronic kidney disease cohorts

(2018) Belinda Spoto et al.   JOURNAL OF HYPERTENSION

Cellular and molecular mechanisms of kidney fibrosis

(2018) Sonja Djudjaj et al.   MOLECULAR ASPECTS OF MEDICINE

Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy

(2018) Sonia Sifuentes-Franco et al.   International Journal of Endocrinology

Oxidative Stress and Renal Fibrosis: Recent Insights for the Development of Novel Therapeutic Strategies

(2018) Wenshan Lv et al.   Frontiers in Physiology

Vascular Dysfunction, Oxidative Stress, and Inflammation in Autosomal Dominant Polycystic Kidney Disease

(2018) Kristen L. Nowak et al.   Clinical Journal of the American Society of Nephrology

Impacts of Indoxyl Sulfate and p-Cresol Sulfate on Chronic Kidney Disease and Mitigating Effects of AST-120

(2018) Wen-Chih Liu et al.   Toxins

Oxidative stress in hemodialysis: Causative mechanisms, clinical implications, and possible therapeutic interventions

(2018) Vassilios Liakopoulos et al.   SEMINARS IN DIALYSIS

Mechanisms and Modulation of Oxidative/Nitrative Stress in Type 4 Cardio-Renal Syndrome and Renal Sarcopenia

(2018) Márta Sárközy et al.   Frontiers in Physiology

Indoxyl sulfate potentiates endothelial dysfunction via reciprocal role for reactive oxygen species and RhoA/ROCK signaling in 5/6 nephrectomized rats

(2017) Shuang Chu et al.   FREE RADICAL RESEARCH

Update on the Burden of CKD

(2017) Josef Coresh   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Superoxide and hydrogen peroxide counterregulate myogenic contractions in renal afferent arterioles from a mouse model of chronic kidney disease

(2017) Lingli Li et al.   KIDNEY INTERNATIONAL

Postconditioning protects renal fibrosis by attenuating oxidative stress-induced mitochondrial injury

(2017) Shuxian Zhang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Oxidative Stress in Patients Undergoing Peritoneal Dialysis: A Current Review of the Literature

(2017) Vassilios Liakopoulos et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms—Biomarkers—Interventions, and Future Perspectives

(2017) Paraskevi Pavlakou et al.   Oxidative Medicine and Cellular Longevity

Chronic Kidney Disease and Disproportionally Increased Cardiovascular Damage: Does Oxidative Stress Explain the Burden?

(2017) Anila Duni et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress in Hemodialysis Patients: A Review of the Literature

(2017) Vassilios Liakopoulos et al.   Oxidative Medicine and Cellular Longevity

Diabetes and Kidney Disease: Role of Oxidative Stress

(2016) Jay C. Jha et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of Renal Oxidative Stress in the Pathogenesis of the Cardiorenal Syndrome

(2016) Beverly Giam et al.   Heart Lung and Circulation

Podocyte injury and its consequences

(2016) Michio Nagata   KIDNEY INTERNATIONAL

A Genetic Biomarker of Oxidative Stress, the Paraoxonase-1 Q192R Gene Variant, Associates with Cardiomyopathy in CKD: A Longitudinal Study

(2016) E. Dounousi et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress Biomarkers and Left Ventricular Hypertrophy in Children with Chronic Kidney Disease

(2016) Dorota Drożdż et al.   Oxidative Medicine and Cellular Longevity

Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy

(2015) Jay C. Jha et al.   DIABETOLOGIA

Advanced oxidation protein products induce apoptosis in podocytes through induction of endoplasmic reticulum stress

(2015) Guang Rong et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Extracellular Superoxide Dismutase Protects against Proteinuric Kidney Disease

(2015) R. J. Tan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protein carbamylation is associated with heart failure and mortality in diabetic patients with end-stage renal disease

(2015) Christiane Drechsler et al.   KIDNEY INTERNATIONAL

Origin of myofibroblasts and cellular events triggering fibrosis

(2015) Matthias Mack et al.   KIDNEY INTERNATIONAL

p47phox contributes to albuminuria and kidney fibrosis in mice

(2015) Hongtao Wang et al.   KIDNEY INTERNATIONAL

New insights into the mechanisms of podocyte health

(2015) Jeffrey H. Miner   Nature Reviews Nephrology

Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease

(2015) Lili Zhou et al.   Nature Reviews Nephrology

Pro-inflammatory cytokines and leukocyte oxidative burst in chronic kidney disease: culprits or innocent bystanders?

(2015) Nathalie Neirynck et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Chronic Kidney Disease Influences Multiple Systems: Describing the Relationship between Oxidative Stress, Inflammation, Kidney Damage, and Concomitant Disease

(2015) Patrick S. Tucker et al.   Oxidative Medicine and Cellular Longevity

The balance of powers: Redox regulation of fibrogenic pathways in kidney injury

(2015) Daryl M. Okamura et al.   Redox Biology

Oxidative stress and autophagy: Crucial modulators of kidney injury

(2015) Angara Sureshbabu et al.   Redox Biology

Protein-bound Uremic Toxins, Inflammation and Oxidative Stress: A Cross-sectional Study in Stage 3–4 Chronic Kidney Disease

(2014) Megan Rossi et al.   ARCHIVES OF MEDICAL RESEARCH

Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis

(2014) Ilse Daehn et al.   JOURNAL OF CLINICAL INVESTIGATION

Increase in AMPK brought about by cocoa is renoprotective in experimental diabetes mellitus by reducing NOX4/TGFβ-1 signaling

(2014) Alexandros Papadimitriou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mutual Antagonism of Wilms' Tumor 1 and  -Catenin Dictates Podocyte Health and Disease

(2014) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy

(2014) J. C. Jha et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/ -Catenin Signaling

(2014) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy Regulates TGF-  Expression and Suppresses Kidney Fibrosis Induced by Unilateral Ureteral Obstruction

(2014) Y. Ding et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Effect of Redox Modulating NRF2 Activators on Chronic Kidney Disease

(2014) Bo-hyun Choi et al.   MOLECULES

High Glucose Induces Podocyte Injury via Enhanced (Pro)renin Receptor-Wnt-β-Catenin-Snail Signaling Pathway

(2014) Caixia Li et al.   PLoS One

The progress of inflammation and oxidative stress in patients with chronic kidney disease

(2014) Gaosi Xu et al.   RENAL FAILURE

Novel aspects of ROS signalling in heart failure

(2013) Anne D. Hafstad et al.   BASIC RESEARCH IN CARDIOLOGY

Clinical and research markers of oxidative stress in chronic kidney disease

(2013) Patrick Steven Tucker et al.   BIOMARKERS

Pathogenesis of Chronic Cardiorenal Syndrome: Is There a Role for Oxidative Stress?

(2013) Speranza Rubattu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nox4 NADPH Oxidase Mediates Peroxynitrite-dependent Uncoupling of Endothelial Nitric-oxide Synthase and Fibronectin Expression in Response to Angiotensin II

(2013) Doug-Yoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH Oxidases, Reactive Oxygen Species, and the Kidney: Friend and Foe

(2013) M. Sedeek et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease

(2013) Stacey Ruiz et al.   KIDNEY INTERNATIONAL

Sestrin 2 and AMPK Connect Hyperglycemia to Nox4-Dependent Endothelial Nitric Oxide Synthase Uncoupling and Matrix Protein Expression

(2013) Assaad A. Eid et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy

(2013) Mohammad A. Aminzadeh et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Nrf2 pathway in the progression of renal disease

(2013) C. Zoja et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Contribution of genetics and epigenetics to progression of kidney fibrosis

(2013) B. Tampe et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Asymmetric Dimethylarginine, Endothelial Dysfunction and Renal Disease

(2012) Luis Aldámiz-Echevarría et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

eNOS Deficiency Predisposes Podocytes to Injury in Diabetes

(2012) D. A. Yuen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH-Oxidase 4 Protects against Kidney Fibrosis during Chronic Renal Injury

(2012) S. Nlandu Khodo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Interaction of receptor for advanced glycation end products with advanced oxidation protein products induces podocyte injury

(2012) Yasuhiko Yamamoto et al.   KIDNEY INTERNATIONAL

The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis

(2012) Li Li Zhou et al.   KIDNEY INTERNATIONAL

SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2Akita diabetic mice

(2012) Hiroki Fujita et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway

(2012) Vivian Soetikno et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Oxidative stress, anti-oxidant therapies and chronic kidney disease

(2012) DAVID M SMALL et al.   NEPHROLOGY

Cellular and molecular mechanisms of diabetic glomerulopathy

(2012) Luigi Gnudi   NEPHROLOGY DIALYSIS TRANSPLANTATION

Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus

(2011) Sherene M. Shenouda et al.   CIRCULATION

Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure

(2011) Dao-Fu Dai et al.   CIRCULATION RESEARCH

Oxidative Stress and Galactose-Deficient IgA1 as Markers of Progression in IgA Nephropathy

(2011) R. Camilla et al.   Clinical Journal of the American Society of Nephrology

Advanced oxidation protein products (AOPP): novel uremic toxins, or components of the non-enzymatic antioxidant system of the plasma proteome?

(2011) László Selmeci   FREE RADICAL RESEARCH

Superoxide Modulates Myogenic Contractions of Mouse Afferent Arterioles

(2011) En Yin Lai et al.   HYPERTENSION

p47 phox Is Required for Afferent Arteriolar Contractile Responses to Angiotensin II and Perfusion Pressure in Mice

(2011) En Yin Lai et al.   HYPERTENSION

Physiological Relevance of Antioxid/Redox Genes; Learning from Genetically Modified Animals Guest Editor: Junichi Fujii Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme

(2011) Masato Katsuyama et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Luminal Alkalinization Attenuates Proteinuria-Induced Oxidative Damage in Proximal Tubular Cells

(2011) T. Souma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TRPC6 Enhances Angiotensin II-induced Albuminuria

(2011) J. Eckel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Matrix Metalloproteinase-7 as a Surrogate Marker Predicts Renal Wnt/ -Catenin Activity in CKD

(2011) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases

(2011) Jeffrey L. Barnes et al.   KIDNEY INTERNATIONAL

Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts

(2011) Marije van der Velde et al.   KIDNEY INTERNATIONAL

Estimated Glomerular Filtration Rate and the Risk of Major Vascular Events and All-Cause Mortality: A Meta-Analysis

(2011) Marion Mafham et al.   PLoS One

Inflammation, Oxidative Stress, and Insulin Resistance in Polycystic Kidney Disease

(2010) V. Menon et al.   Clinical Journal of the American Society of Nephrology

NADPH oxidase activity is associated with cardiac osteopontin and pro-collagen type I expression in uremia

(2010) Aurélie Goux et al.   FREE RADICAL RESEARCH

Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Delayed Treatment Effects of Xanthine Oxidase Inhibition on Systolic Overload-Induced Left Ventricular Hypertrophy and Dysfunction

(2010) X. Xu et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Reduction of Renal Superoxide Dismutase in Progressive Diabetic Nephropathy

(2009) H. Fujita et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Accumulation of advanced oxidation protein products induces podocyte apoptosis and deletion through NADPH-dependent mechanisms

(2009) Li Li Zhou et al.   KIDNEY INTERNATIONAL

Asymmetric Dimethylarginine and Lipid Peroxidation Products in Early Autosomal Dominant Polycystic Kidney Disease

(2008) Dan Wang et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Role of NOX2 in the regulation of afferent arteriole responsiveness

(2008) Mattias Carlström et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes

(2008) J. M. Forbes et al.   DIABETES

Cardiorenal Syndrome

(2008) Claudio Ronco et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease

(2008) Victoria Cachofeiro et al.   KIDNEY INTERNATIONAL