Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney

HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice

(2016) Bijaya K. Nayak et al.   DIABETES

Hypoxia-inducible factor-1α promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3

(2016) Bethany Baumann et al.   KIDNEY INTERNATIONAL

Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition

(2016) Dipayan Chaudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia

(2015) Hyun-Yoo Joo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Snail Is a Direct Target of Hypoxia-inducible Factor 1α (HIF1α) in Hypoxia-induced Endothelial to Mesenchymal Transition of Human Coronary Endothelial Cells

(2015) Xingbo Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Transcription Factor Acetylation in Diabetic Kidney Disease

(2014) R. Liu et al.   DIABETES

The Association Between Age and Nephrosclerosis on Renal Biopsy Among Healthy Adults

(2013) Andrew D. Rule   ANNALS OF INTERNAL MEDICINE

3,5-Diiodo-l-thyronine ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats

(2013) Guoguo Shang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia–reperfusion injury

(2013) Jason A. Funk et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sirtuins and renal diseases: relationship with aging and diabetic nephropathy

(2012) Munehiro Kitada et al.   CLINICAL SCIENCE

Age-Associated Molecular Changes in the Kidney in Aged Mice

(2012) Ji Hee Lim et al.   Oxidative Medicine and Cellular Longevity

Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions

(2012) Alexander Laemmle et al.   PLoS One

Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis

(2011) Shin-ichiro Imai   FEBS LETTERS

Kidney aging—inevitable or preventable?

(2011) Devasmita Choudhury et al.   Nature Reviews Nephrology

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

Alteration of Forkhead Box O (Foxo4) Acetylation Mediates Apoptosis of Podocytes in Diabetes Mellitus

(2011) Peter Y. Chuang et al.   PLoS One

Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function

(2010) Kazuhiro Hasegawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirt1 activation protects the mouse renal medulla from oxidative injury

(2010) Wenjuan He et al.   JOURNAL OF CLINICAL INVESTIGATION

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1

(2009) Guofei Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Xenon Preconditioning Protects against Renal Ischemic-Reperfusion Injury via HIF-1  Activation

(2009) D. Ma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of Hypoxia-Inducible Factor 2  Signaling by the Stress-Responsive Deacetylase Sirtuin 1

(2009) E. M. Dioum et al.   SCIENCE

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

Transcriptional targets of sirtuins in the coordination of mammalian physiology

(2008) Jerome N Feige et al.   CURRENT OPINION IN CELL BIOLOGY

HIF Activation Protects From Acute Kidney Injury

(2008) A. Weidemann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypoxia and Hypoxia-Inducible Factor in Renal Disease

(2008) Masaomi Nangaku et al.   NEPHRON EXPERIMENTAL NEPHROLOGY