3D Bioprinted Osteogenic Tissue Models for In Vitro Drug Screening

Inhibition of MEK/ERK upregulates GSH production and increases RANKL-induced osteoclast differentiation in RAW 264.7 cells

(2020) Taiwo Samuel Agidigbi et al.   FREE RADICAL RESEARCH

Smoothened agonist sterosome immobilized hybrid scaffold for bone regeneration

(2020) Chung-Sung Lee et al.   Science Advances

Osteogenic Enhancement Between Icariin and Bone Morphogenetic Protein 2: A Potential Osteogenic Compound for Bone Tissue Engineering

(2019) Xin Zhang et al.   Frontiers in Pharmacology

Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways

(2019) Xudong Yao et al.   Frontiers in Pharmacology

3D bioprinting for high-throughput screening: Drug screening, disease modeling, and precision medicine applications

(2019) Andrea Mazzocchi et al.   Applied Physics Reviews

Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway

(2019) Qi Cui et al.   Cell Death & Disease

Electronic cigarette liquid exposure induces flavor-dependent osteotoxicity and increases expression of a key bone marker, collagen type I

(2019) Claire E. Otero et al.   JOURNAL OF APPLIED TOXICOLOGY

The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis

(2019) Jung-Min Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanism of Action of Icariin in Bone Marrow Mesenchymal Stem Cells

(2019) Aofei Yang et al.   Stem Cells International

Differential effects of MEK inhibitors on rat neural stem cell differentiation: Repressive roles of MEK2 in neurogenesis and induction of astrocytogenesis by PD98059

(2019) Ha-Rim Lee et al.   PHARMACOLOGICAL RESEARCH

Key components of engineering vascularized 3-dimensional bioprinted bone constructs

(2019) Fahimeh Shahabipour et al.   Translational Research

Characterization and immunogenicity of bone marrow-derived mesenchymal stem cells under osteoporotic conditions

(2019) Yingkang Huang et al.   Science China-Life Sciences

Small molecules for mesenchymal stem cell fate determination

(2019) Yu-Hao Cheng et al.   World Journal of Stem Cells

Porous composite scaffold incorporating osteogenic phytomolecule icariin for promoting skeletal regeneration in challenging osteonecrotic bone in rabbits

(2018) Yuxiao Lai et al.   BIOMATERIALS

The key role of proinflammatory cytokines, matrix proteins, RANKL/OPG and Wnt/β-catenin in bone healing of hip arthroplasty patients

(2018) Jean Cassuto et al.   BONE

Icariin abrogates osteoclast formation through the regulation of the RANKL-mediated TRAF6/NF-κB/ERK signaling pathway in Raw264.7 cells.

(2018) Buyun Kim et al.   PHYTOMEDICINE

Engineering in-vitro stem cell-based vascularized bone models for drug screening and predictive toxicology

(2018) Alessandro Pirosa et al.   Stem Cell Research & Therapy

Icariin Regulates the Bidirectional Differentiation of Bone Marrow Mesenchymal Stem Cells through Canonical Wnt Signaling Pathway

(2017) Jun-ming Huang et al.   Evidence-based Complementary and Alternative Medicine

Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low–molecular weight protein tyrosine phosphatase

(2017) Joji Kusuyama et al.   MOLECULAR BIOLOGY OF THE CELL

Modeling Physiological Events in 2D vs. 3D Cell Culture

(2017) Kayla Duval et al.   PHYSIOLOGY

Baicalein and U0126 suppress bladder cancer proliferation via MAPK signaling pathway

(2017) Xiaoping Tang et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery

(2016) Ryan Trombetta et al.   ANNALS OF BIOMEDICAL ENGINEERING

3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening

(2016) Joseph Vanderburgh et al.   ANNALS OF BIOMEDICAL ENGINEERING

Disturbed MEK/ERK signaling increases osteoclast activity via the Hedgehog-Gli pathway in postmenopausal osteoporosis

(2016) Xiaojie Li et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Imaging Findings of Metabolic Bone Disease

(2016) Connie Y. Chang et al.   RADIOGRAPHICS

Bioprinting towards Physiologically Relevant Tissue Models for Pharmaceutics

(2016) Weijie Peng et al.   TRENDS IN BIOTECHNOLOGY

The effect of purmorphamine on differentiation of endometrial stem cells into osteoblast-like cells on collagen/hydroxyapatite scaffolds

(2016) Naghmeh Bahrami et al.   Artificial Cells Nanomedicine and Biotechnology

Activation of the Extracellular Signal-Regulated Kinase Signaling Is Critical for Human Umbilical Cord Mesenchymal Stem Cell Osteogenic Differentiation

(2016) Chen-Shuang Li et al.   Biomed Research International

Small molecules and their controlled release that induce the osteogenic/chondrogenic commitment of stem cells

(2015) Yingjun Wang et al.   BIOTECHNOLOGY ADVANCES

Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo

(2015) Meiling Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Changes in Bone Metabolism in Morbidly Obese Patients After Bariatric Surgery: A Meta-Analysis

(2015) Cong Liu et al.   OBESITY SURGERY

Small molecule stimulation enhances bone regeneration but not titanium implant osseointegration

(2013) Kris Gellynck et al.   BONE

Epiregulin can promote proliferation of stem cells from the dental apical papillaviaMEK/Erk and JNK signalling pathways

(2013) Y. Cao et al.   CELL PROLIFERATION

Effect of purmorphamine on human osteoclast activity and gene expression

(2009) L.S. Bellesini et al.   BONE

A new bone repair scaffold combined with chitosan/hydroxyapatite and sustained releasing icariin

(2009) Tao Wu et al.   CHINESE SCIENCE BULLETIN

Hedgehog Signaling Alters Adipocyte Maturation of Human Mesenchymal Stem Cells

(2008) Coralie Fontaine et al.   STEM CELLS