Advances in actinomycete research: an ActinoBase review of 2019

Metabolic engineering strategies based on secondary messengers (p)ppGpp and c-di-GMP to increase erythromycin yield in Saccharopolyspora erythraea

(2019) Zhen Xu et al.   ACS Synthetic Biology

Microbial diversity of a Himalayan forest and characterization of rare actinomycetes for antimicrobial compounds

(2019) Nidhi Srivastava et al.   3 Biotech

The antimicrobial potential of Streptomyces from insect microbiomes

(2019) Marc G. Chevrette et al.   Nature Communications

Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool

(2019) Javier Santos-Aberturas et al.   NUCLEIC ACIDS RESEARCH

Phylogenetic analyses of antibiotic-producing Streptomyces sp. isolates obtained from the stingless-bee Tetragonisca angustula (Apidae: Meliponini)

(2019) Juan Carlos Cambronero-Heinrichs et al.   MICROBIOLOGY-SGM

Salinipeptins: Integrated Genomic and Chemical Approaches Reveal Unusual d-Amino Acid-Containing Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) from a Great Salt Lake Streptomyces sp.

(2019) Zhuo Shang et al.   ACS Chemical Biology

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

(2019) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Uncovering the potential of novel micromonosporae isolated from an extreme hyper-arid Atacama Desert soil

(2019) Lorena Carro et al.   Scientific Reports

Sensing and responding to diverse extracellular signals: an updated analysis of the sensor kinases and response regulators of Streptomyces species

(2019) Thomas C. McLean et al.   MICROBIOLOGY-SGM

Overexpression of the diguanylate cyclase CdgD blocks developmental transitions and antibiotic biosynthesis in Streptomyces coelicolor

(2019) Xiaocao Liu et al.   Science China-Life Sciences

Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2

(2019) Emma J Gehrke et al.   eLife

Biocontrol of Cereal Crop Diseases Using Streptomycetes

(2019) Jake T. Newitt et al.   Pathogens

Nucleotide second messengers in Streptomyces

(2019) Andreas Latoscha et al.   MICROBIOLOGY-SGM

Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST

(2019) Yaojun Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance

(2019) Nicholas Waglechner et al.   Nature Microbiology

Local Adaptation of Bacterial Symbionts within a Geographic Mosaic of Antibiotic Coevolution

(2019) Eric J. Caldera et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Streptomyces griseocarneus R132 controls phytopathogens and promotes growth of pepper (Capsicum annuum)

(2019) Rhavena Graziela Liotti et al.   BIOLOGICAL CONTROL

Awakening ancient polar Actinobacteria: diversity, evolution and specialized metabolite potential

(2019) Natalie Millán-Aguiñaga et al.   MICROBIOLOGY-SGM

Actinobacterial community in Shuanghe Cave using culture-dependent and -independent approaches

(2019) Yunchuan Long et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

A mutualistic interaction between Streptomyces bacteria, strawberry plants and pollinating bees

(2019) Da-Ran Kim et al.   Nature Communications

c-di-GMP Arms an Anti-σ to Control Progression of Multicellular Differentiation in Streptomyces

(2019) Kelley A. Gallagher et al.   MOLECULAR CELL

MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities

(2019) Liu Cao et al.   Cell Systems

Comparison of Actinomycete Community Composition on the Surface and Inside of Japanese Black Pine (Pinus thunbergii) Tree Roots Colonized by the Ectomycorrhizal Fungus Cenococcum geophilum

(2018) Shoyo Sakoda et al.   MICROBIAL ECOLOGY

A phylogenetic and evolutionary analysis of antimycin biosynthesis

(2018) Rebecca Joynt et al.   MICROBIOLOGY-SGM

Mycobacterial biomaterials and resources for researchers

(2018) Manzour Hernando Hazbón et al.   Pathogens and Disease

Emerging evolutionary paradigms in antibiotic discovery

(2018) Marc G. Chevrette et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Screening and identification of novel isolate Streptomyces sp., NLKPB45 from Nellore costal region for its biomedical applications

(2018) B. Sudha Kalyani et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Characterisation of the mode of action of Aurodox, a Type III Secretion System inhibitor from Streptomyces goldiniensis

(2018) Rebecca E McHugh et al.   INFECTION AND IMMUNITY

Screening of rare actinomycetes isolated from natural wetland ecosystem (Fetzara Lake, northeastern Algeria) for hydrolytic enzymes and antimicrobial activities

(2018) Mabrouka Benhadj et al.   JOURNAL OF KING SAUD UNIVERSITY SCIENCE

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

A new genome-mining tool redefines the lasso peptide biosynthetic landscape

(2017) Jonathan I Tietz et al.   Nature Chemical Biology

CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations

(2017) Cem Kuscu et al.   NATURE METHODS

The Antibiotic Resistant Target Seeker (ARTS), an exploration engine for antibiotic cluster prioritization and novel drug target discovery

(2017) Mohammad Alanjary et al.   NUCLEIC ACIDS RESEARCH

antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification

(2017) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants

(2017) Zhiwei Qin et al.   Chemical Science

Targeted isolation of sulfur-containing metabolites from Lsr2-deletion mutant strain of Streptomyces roseosporus

(2017) Lina Deng et al.   RSC Advances

Gifted microbes for genome mining and natural product discovery

(2016) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Next Generation Sequencing of Actinobacteria for the Discovery of Novel Natural Products

(2016) Juan Gomez-Escribano et al.   Marine Drugs

The evolution of genome mining in microbes – a review

(2016) Nadine Ziemert et al.   NATURAL PRODUCT REPORTS

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

(2016) Mingxun Wang et al.   NATURE BIOTECHNOLOGY

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

(2016) F. Jiang et al.   SCIENCE

Coordinate Regulation of Antimycin and Candicidin Biosynthesis

(2016) Thomas C. McLean et al.   mSphere

Taxonomy, Physiology, and Natural Products of Actinobacteria

(2015) Essaid Ait Barka et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate

(2015) Mostafa E. Rateb et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

(2014) Natalia Tschowri et al.   CELL

High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System

(2014) Ryan E. Cobb et al.   ACS Synthetic Biology

A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis

(2014) Marnix H. Medema et al.   PLoS Computational Biology

Pseudonocardia sediminis sp. nov., isolated from marine sediment

(2013) D.-F. Zhang et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Glycopeptide antibiotic biosynthesis

(2013) Grace Yim et al.   JOURNAL OF ANTIBIOTICS

Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites

(2013) Mamoru Komatsu et al.   ACS Synthetic Biology

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

Revealing structure and assembly cues for Arabidopsis root-inhabiting bacterial microbiota

(2012) Davide Bulgarelli et al.   NATURE

Challenges of Antibacterial Discovery

(2011) L. L. Silver   CLINICAL MICROBIOLOGY REVIEWS

The energy–diversity relationship of complex bacterial communities in Arctic deep-sea sediments

(2011) Christina Bienhold et al.   ISME Journal

Biosynthesis and Regulation of Grisemycin, a New Member of the Linaridin Family of Ribosomally Synthesized Peptides Produced by Streptomyces griseus IFO 13350

(2011) J. Claesen et al.   JOURNAL OF BACTERIOLOGY

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Use of Ichip for High-Throughput In Situ Cultivation of "Uncultivable" Microbial Species

(2010) D. Nichols et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus

(2010) Jörg Barke et al.   BMC BIOLOGY

A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium

(2010) Kyota Kimura et al.   JOURNAL OF ANTIBIOTICS

Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides

(2010) J. Claesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

(2010) Rachel E. Haurwitz et al.   SCIENCE

Global pollinator declines: trends, impacts and drivers

(2010) Simon G. Potts et al.   TRENDS IN ECOLOGY & EVOLUTION

Candicidin-producing Streptomyces support leaf-cutting ants to protect their fungus garden against the pathogenic fungus Escovopsis

(2009) S. Haeder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variation in Pseudonocardia antibiotic defence helps govern parasite-induced morbidity in Acromyrmex leaf-cutting ants

(2009) Michael Poulsen et al.   Environmental Microbiology Reports

Lsr2 of Mycobacterium Represents a Novel Class of H-NS-Like Proteins

(2008) B. R. G. Gordon et al.   JOURNAL OF BACTERIOLOGY

PCR-amplification of GC-rich regions: 'slowdown PCR'

(2008) Ulrich H Frey et al.   Nature Protocols