Microstructure, pathophysiology, and potential therapeutics of COVID‐19: A comprehensive review
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Title
Microstructure, pathophysiology, and potential therapeutics of COVID‐19: A comprehensive review
Authors
Keywords
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Journal
JOURNAL OF MEDICAL VIROLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-07-03
DOI
10.1002/jmv.26254
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Note: Only part of the references are listed.- Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
- (2020) Aiping Wu et al. Cell Host & Microbe
- Epitopes for a 2019-nCoV vaccine
- (2020) Guglielmo Lucchese Cellular & Molecular Immunology
- Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia
- (2020) Daniel K W Chu et al. CLINICAL CHEMISTRY
- Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR
- (2020) Victor M Corman et al. Eurosurveillance
- Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
- (2020) Haibo Zhang et al. INTENSIVE CARE MEDICINE
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
- (2020) Dawei Wang et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
- (2020) Hussin A. Rothan et al. JOURNAL OF AUTOIMMUNITY
- The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus
- (2020) Calvin J Gordon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recent insights into 2019-nCoV: a brief but comprehensive review
- (2020) Qingmei Han et al. JOURNAL OF INFECTION
- Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2
- (2020) Zhixin Liu et al. JOURNAL OF MEDICAL VIROLOGY
- Potential interventions for novel coronavirus in China: A systematic review
- (2020) Lei Zhang et al. JOURNAL OF MEDICAL VIROLOGY
- Understanding of COVID‐19 based on current evidence
- (2020) Pengfei Sun et al. JOURNAL OF MEDICAL VIROLOGY
- Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach
- (2020) Manojit Bhattacharya et al. JOURNAL OF MEDICAL VIROLOGY
- Immunoinformatics‐aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019‐nCoV
- (2020) Vargab Baruah et al. JOURNAL OF MEDICAL VIROLOGY
- 2019 novel coronavirus disease (COVID-19) in Taiwan: Reports of two cases from Wuhan, China
- (2020) Wei-Hsuan Huang et al. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
- Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS
- (2020) Yushun Wan et al. JOURNAL OF VIROLOGY
- 2019-nCoV transmission through the ocular surface must not be ignored
- (2020) Cheng-wei Lu et al. LANCET
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- A distinct name is needed for the new coronavirus
- (2020) Shibo Jiang et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Convalescent plasma as a potential therapy for COVID-19
- (2020) Long Chen et al. LANCET INFECTIOUS DISEASES
- Anti-HCV, nucleotide inhibitors, repurposing against COVID-19
- (2020) Abdo A. Elfiky LIFE SCIENCES
- Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China
- (2020) Fei Yu et al. MICROBES AND INFECTION
- Coronavirus puts drug repurposing on the fast track
- (2020) Charlotte Harrison NATURE BIOTECHNOLOGY
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- (2020) Qun Li et al. NEW ENGLAND JOURNAL OF MEDICINE
- Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
- (2020) Emmie de Wit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- New coronavirus threat galvanizes scientists
- (2020) Jon Cohen SCIENCE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission
- (2020) Xintian Xu et al. Science China-Life Sciences
- Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein
- (2020) Junghyun Goo et al. VIRUS RESEARCH
- Characterization of the Immune Response of MERS-CoV Vaccine Candidates Derived from Two Different Vectors in Mice
- (2020) Entao Li et al. Viruses-Basel
- Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies
- (2020) Syed Faraz Ahmed et al. Viruses-Basel
- Transmission routes of 2019-nCoV and controls in dental practice
- (2020) Xian Peng et al. International Journal of Oral Science
- Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity
- (2020) Weilie Chen et al. Emerging Microbes & Infections
- An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies
- (2020) Shibo Jiang et al. Emerging Microbes & Infections
- Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
- (2020) Jasper Fuk-Woo Chan et al. Emerging Microbes & Infections
- Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review
- (2020) Junxiong Pang et al. Journal of Clinical Medicine
- Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection
- (2020) Junwen Luan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- COVID-19 infection: the perspectives on immune responses
- (2020) Yufang Shi et al. CELL DEATH AND DIFFERENTIATION
- A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2
- (2020) Alba Grifoni et al. Cell Host & Microbe
- Functional exhaustion of antiviral lymphocytes in COVID-19 patients
- (2020) Meijuan Zheng et al. Cellular & Molecular Immunology
- NKG2A and COVID-19: another brick in the wall
- (2020) Luca Antonioli et al. Cellular & Molecular Immunology
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- (2020) Li-Li Ren et al. CHINESE MEDICAL JOURNAL
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- (2020) D. Paraskevis et al. INFECTION GENETICS AND EVOLUTION
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- (2020) Daniel E. Leisman et al. INTENSIVE CARE MEDICINE
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- (2020) Dae-Gyun Ahn et al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- COVID-19: towards controlling of a pandemic
- (2020) Juliet Bedford et al. LANCET
- Endothelial cell infection and endotheliitis in COVID-19
- (2020) Zsuzsanna Varga et al. LANCET
- COVID-19: consider cytokine storm syndromes and immunosuppression
- (2020) Puja Mehta et al. LANCET
- Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform
- (2020) Tran Thi Nhu Thao et al. NATURE
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice
- (2020) Linlin Bao et al. NATURE
- Convalescent serum lines up as first-choice treatment for coronavirus
- (2020) Cormac Sheridan NATURE BIOTECHNOLOGY
- CRISPR–Cas12-based detection of SARS-CoV-2
- (2020) James P. Broughton et al. NATURE BIOTECHNOLOGY
- Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
- (2020) Irani Thevarajan et al. NATURE MEDICINE
- Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
- (2020) Maximilian Ackermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Developing Covid-19 Vaccines at Pandemic Speed
- (2020) Nicole Lurie et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effectiveness of convalescent plasma therapy in severe COVID-19 patients
- (2020) Kai Duan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
- (2020) Shutoku Matsuyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Possible method for the production of a Covid-19 vaccine
- (2020) Aung Myint et al. VETERINARY RECORD
- Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
- (2020) Xiuyuan Ou et al. Nature Communications
- Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review
- (2020) Anwar M. Hashem et al. Travel Medicine and Infectious Disease
- COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics
- (2020) Kuldeep Dhama et al. Human Vaccines & Immunotherapeutics
- Design of a Multiepitope-Based Peptide Vaccine against the E Protein of Human COVID-19: An Immunoinformatics Approach
- (2020) Miyssa I. Abdelmageed et al. Biomed Research International
- Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review
- (2020) Sasmita Poudel Adhikari et al. Infectious Diseases of Poverty
- COVID-19 cytokine storm: the interplay between inflammation and coagulation
- (2020) Ricardo J Jose et al. Lancet Respiratory Medicine
- Humoral Immune Responses in COVID-19 Patients: A Window on the State of the Art
- (2020) Gabriel Siracusano et al. Frontiers in Immunology
- Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)
- (2020) Bo Diao et al. Frontiers in Immunology
- Assay Techniques and Test Development for COVID-19 Diagnosis
- (2020) Linda J. Carter et al. ACS Central Science
- Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
- (2020) Cynthia Liu et al. ACS Central Science
- Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
- (2020) Jia Liu et al. Cell Discovery
- Progress and Prospects on Vaccine Development against SARS-CoV-2
- (2020) Jinyong Zhang et al. Vaccines
- Molecular immune pathogenesis and diagnosis of COVID-19
- (2020) Xiaowei Li et al. Journal of Pharmaceutical Analysis
- In Vitro Diagnostic Assays for COVID-19: Recent Advances and Emerging Trends
- (2020) Sandeep Kumar Vashist Diagnostics
- COVID-19: Immunology and treatment options
- (2020) Susanna Felsenstein et al. CLINICAL IMMUNOLOGY
- Genetic diversity and evolution of SARS-CoV-2
- (2020) Tung Phan INFECTION GENETICS AND EVOLUTION
- Innate immunity in COVID-19 patients mediated by NKG2A receptors, and potential treatment using Monalizumab, Cholroquine, and antiviral agents
- (2020) Ahmed Yaqinuddin et al. MEDICAL HYPOTHESES
- Efficacy of an Adjuvanted Middle East Respiratory Syndrome Coronavirus Spike Protein Vaccine in Dromedary Camels and Alpacas
- (2019) Danielle Adney et al. Viruses-Basel
- Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirus
- (2019) Myung Hee Kim et al. PLoS One
- Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors
- (2019) Robert N. Kirchdoerfer et al. Nature Communications
- A Fusion Peptide in the Spike Protein of MERS Coronavirus
- (2019) Entedar A. J. Alsaadi et al. Viruses-Basel
- Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD
- (2019) Nianshuang Wang et al. Cell Reports
- Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus
- (2019) Chean Yeah Yong et al. Frontiers in Microbiology
- The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity
- (2019) Natacha S. Ogando et al. Frontiers in Microbiology
- Monalizumab: inhibiting the novel immune checkpoint NKG2A
- (2019) Thorbald van Hall et al. Journal for ImmunoTherapy of Cancer
- Identification of the immunodominant neutralizing regions in the spike glycoprotein of porcine deltacoronavirus
- (2019) Rui Chen et al. VIRUS RESEARCH
- Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
- (2018) Mario Mauthe et al. Autophagy
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Human transbodies that interfere with the functions of Ebola virus VP35 protein in genome replication and transcription and innate immune antagonism
- (2018) Watee Seesuay et al. Emerging Microbes & Infections
- Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection
- (2018) Rekha Khandia et al. Frontiers in Immunology
- Why are RNA virus mutation rates so damn high?
- (2018) Siobain Duffy PLOS BIOLOGY
- Origin and evolution of pathogenic coronaviruses
- (2018) Jie Cui et al. NATURE REVIEWS MICROBIOLOGY
- Cross-neutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses
- (2017) Lei-Ping Zeng et al. Science China-Life Sciences
- The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection
- (2017) Lan Jiaming et al. VACCINE
- Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy
- (2015) Palash Bhattacharya et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes
- (2015) Hui Hui Wong et al. JOURNAL OF VIROLOGY
- Structural basis and functional analysis of the SARS coronavirus nsp14–nsp10 complex
- (2015) Yuanyuan Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interferon gamma-induced protein 10 is associated with insulin resistance and incident diabetes in patients with nonalcoholic fatty liver disease
- (2015) Chia-Chu Chang et al. Scientific Reports
- Epitope-Based Vaccine Target Screening against Highly Pathogenic MERS-CoV: An In Silico Approach Applied to Emerging Infectious Diseases
- (2015) Jiandong Shi et al. PLoS One
- Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins
- (2014) Sheng-Fan Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Correlation between Pro- and Anti-Inflammatory Cytokines in Chronic Subdural Hematoma Patients Assessed with Factor Analysis
- (2014) Are Hugo Pripp et al. PLoS One
- The Coronavirus Nucleocapsid Is a Multifunctional Protein
- (2014) Ruth McBride et al. Viruses-Basel
- Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis
- (2014) Jose L. Nieto-Torres et al. PLoS Pathogens
- IFITM-Family Proteins: The Cell's First Line of Antiviral Defense
- (2014) Charles C. Bailey et al. Annual Review of Virology
- Middle East Respiratory Syndrome Coronavirus Infection Mediated by the Transmembrane Serine Protease TMPRSS2
- (2013) Kazuya Shirato et al. JOURNAL OF VIROLOGY
- A decade after SARS: strategies for controlling emerging coronaviruses
- (2013) Rachel L. Graham et al. NATURE REVIEWS MICROBIOLOGY
- Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
- (2012) Charles A. Dinarello et al. NATURE REVIEWS DRUG DISCOVERY
- TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells
- (2010) Ya-Wen Chen et al. AMERICAN JOURNAL OF PATHOLOGY
- The spike protein of SARS-CoV — a target for vaccine and therapeutic development
- (2009) Lanying Du et al. NATURE REVIEWS MICROBIOLOGY
- Glycogen Synthase Kinase-3 Regulates the Phosphorylation of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein and Viral Replication
- (2008) Chia-Hsin Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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