Tensile force transmitted through LFA‐1 bonds mechanoregulate neutrophil inflammatory response

Advances in Understanding the Immunological Pathways in Psoriasis

(2019) Simona-Roxana Georgescu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Kindlin Is Mechanosensitive: Force-Induced Conformational Switch Mediates Cross-Talk among Integrins

(2019) Zeinab Jahed et al.   BIOPHYSICAL JOURNAL

Calcium signalling and related ion channels in neutrophil recruitment and function

(2018) Roland Immler et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The role of STIM proteins in neutrophil functions

(2018) Nicolas Demaurex et al.   JOURNAL OF PHYSIOLOGY-LONDON

LFA-1 in T Cell Migration and Differentiation

(2018) Brandon L. Walling et al.   Frontiers in Immunology

Neutrophil Mechanosignaling Promotes Integrin Engagement With Endothelial Cells and Motility Within Inflamed Vessels

(2018) Vasilios A. Morikis et al.   Frontiers in Immunology

Structural basis of kindlin-mediated integrin recognition and activation

(2017) Huadong Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanotransduction at the cell-matrix interface

(2017) K.A. Jansen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The role of STIM and ORAI proteins in phagocytic immune cells

(2016) Nicolas Demaurex et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The kindlin family: functions, signaling properties and implications for human disease

(2016) Emanuel Rognoni et al.   JOURNAL OF CELL SCIENCE

Coordinated integrin activation by actin-dependent force during T-cell migration

(2016) Pontus Nordenfelt et al.   Nature Communications

Single-molecule mechanics of protein-labelled DNA handles

(2016) Vivek S Jadhav et al.   Beilstein Journal of Nanotechnology

CD11c/CD18 Signals Very Late Antigen-4 Activation To Initiate Foamy Monocyte Recruitment during the Onset of Hypercholesterolemia

(2015) G. A. Foster et al.   JOURNAL OF IMMUNOLOGY

Store-operated calcium signaling in neutrophils

(2015) R. A. Clemens et al.   JOURNAL OF LEUKOCYTE BIOLOGY

How Endothelial Cells Regulate Transmigration of Leukocytes in the Inflammatory Response

(2014) William A. Muller   AMERICAN JOURNAL OF PATHOLOGY

The multifactorial role of neutrophils in rheumatoid arthritis

(2014) Helen L. Wright et al.   Nature Reviews Rheumatology

STIM1 Positively Regulates the Ca2+ Release Activity of the Inositol 1,4,5-Trisphosphate Receptor in Bovine Aortic Endothelial Cells

(2014) Éric Béliveau et al.   PLoS One

Neutrophil cell surface receptors and their intracellular signal transduction pathways

(2013) Krisztina Futosi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells

(2013) F. A. Moretti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On-chip phenotypic analysis of inflammatory monocytes in atherogenesis and myocardial infarction

(2013) Greg A. Foster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

(2012) C. T. Lefort et al.   BLOOD

Kindlin-3 Mediates Integrin αLβ2 Outside-in Signaling, and It Interacts with Scaffold Protein Receptor for Activated-C Kinase 1 (RACK1)

(2012) Chen Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin bi-directional signaling across the plasma membrane

(2012) Ping Hu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Leukocyte Function Antigen-1, Kindlin-3, and Calcium Flux Orchestrate Neutrophil Recruitment during Inflammation

(2012) N. Dixit et al.   JOURNAL OF IMMUNOLOGY

Neutrophil arrest by LFA-1 activation

(2012) Craig T. Lefort et al.   Frontiers in Immunology

Chemokines, selectins and intracellular calcium flux: temporal and spatial cues for leukocyte arrest

(2012) Neha Dixit et al.   Frontiers in Immunology

Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells

(2011) S. W. Feigelson et al.   BLOOD

RACK1, A multifaceted scaffolding protein: Structure and function

(2011) David R Adams et al.   Cell Communication and Signaling

Polycystin-1, 2, and STIM1 Interact with IP3R to Modulate ER Ca2+ Release through the PI3K/Akt Pathway

(2011) Netty G. Santoso et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Kindlin

(2011) Feng Ye et al.   CURRENT OPINION IN HEMATOLOGY

Migrational Guidance of Neutrophils Is Mechanotransduced via High-Affinity LFA-1 and Calcium Flux

(2011) N. Dixit et al.   JOURNAL OF IMMUNOLOGY

Long-Lived, High-Strength States of ICAM-1 Bonds to β2 Integrin, I: Lifetimes of Bonds to Recombinant αLβ2 Under Force

(2010) Evan Evans et al.   BIOPHYSICAL JOURNAL

Long-Lived, High-Strength States of ICAM-1 Bonds to β2 Integrin, II: Lifetimes of LFA-1 Bonds Under Force in Leukocyte Signaling

(2010) Koji Kinoshita et al.   BIOPHYSICAL JOURNAL

Neutrophils in chronic inflammatory airway diseases: can we target them and how?

(2010) Y. Gernez et al.   EUROPEAN RESPIRATORY JOURNAL

Forcing Switch from Short- to Intermediate- and Long-lived States of the αA Domain Generates LFA-1/ICAM-1 Catch Bonds

(2010) Wei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions

(2009) E. Manevich-Mendelson et al.   BLOOD

Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow

(2009) U. Y. Schaff et al.   BLOOD

TRPC3 Regulates Agonist-stimulated Ca2+Mobilization by Mediating the Interaction between Type I Inositol 1,4,5-Trisphosphate Receptor, RACK1, and Orai1

(2009) Geoffrey E. Woodard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Flux in Neutrophils Synchronizes β2 Integrin Adhesive and Signaling Events that Guide Inflammatory Recruitment

(2008) Ulrich Y. Schaff et al.   ANNALS OF BIOMEDICAL ENGINEERING

RACK1 Regulates the Cell Surface Expression of the G Protein-Coupled Receptor for Thromboxane A2

(2008) Audrey Parent et al.   TRAFFIC