Kindlin-3 Mediates Integrin αLβ2 Outside-in Signaling, and It Interacts with Scaffold Protein Receptor for Activated-C Kinase 1 (RACK1)

Kindlin-2: a novel adhesion protein related to tumor invasion, lymph node metastasis, and patient outcome in gastric cancer

(2011) Zhanlong Shen et al.   AMERICAN JOURNAL OF SURGERY

Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells

(2011) S. W. Feigelson et al.   BLOOD

The integrin coactivator Kindlin-2 plays a critical role in angiogenesis in mice and zebrafish

(2011) E. Pluskota et al.   BLOOD

Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins

(2011) H. Qu et al.   JOURNAL OF CELL SCIENCE

Mediation of Rac1 activation by kindlin-2: An essential function in osteoblast adhesion, spreading, and proliferation

(2011) Gil-Yong Jung et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Migfilin and Filamin as Regulators of Integrin Activation in Endothelial Cells and Neutrophils

(2011) Mitali Das et al.   PLoS One

Two mutations in the KINDLIN3 gene of a new leukocyte adhesion deficiency III patient reveal distinct effects on leukocyte function in vitro

(2010) A. McDowall et al.   BLOOD

The Integrin Co-activator Kindlin-3 Is Expressed and Functional in a Non-hematopoietic Cell, the Endothelial Cell

(2010) Katarzyna Bialkowska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Kindlin-2 in Fibroblast Functions: Implications for Wound Healing

(2010) Yinghong He et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1

(2010) J. Rabl et al.   SCIENCE

Kindlin-1 Is Required for RhoGTPase-Mediated Lamellipodia Formation in Keratinocytes

(2009) Cristina Has et al.   AMERICAN JOURNAL OF PATHOLOGY

The Ins and Outs of Leukocyte Integrin Signaling

(2009) Clare L. Abram et al.   Annual Review of Immunology

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions

(2009) E. Manevich-Mendelson et al.   BLOOD

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

(2009) Nicholas J Anthis et al.   EMBO JOURNAL

Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

(2009) David S. Harburger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New PI(4,5)P2- and membrane proximal integrin–binding motifs in the talin head control β3-integrin clustering

(2009) Frédéric Saltel et al.   JOURNAL OF CELL BIOLOGY

Integrins and cell-fate determination

(2009) C. H. Streuli   JOURNAL OF CELL SCIENCE

On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes

(2009) R. Rajamanonmani et al.   JOURNAL OF GENERAL VIROLOGY

The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation

(2009) Benjamin T. Goult et al.   JOURNAL OF MOLECULAR BIOLOGY

Kindlin-3 is required for β2 integrin–mediated leukocyte adhesion to endothelial cells

(2009) Markus Moser et al.   NATURE MEDICINE

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans

(2009) Nikolay L Malinin et al.   NATURE MEDICINE

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation

(2009) Lena Svensson et al.   NATURE MEDICINE

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

The Kindlin protein family: new members to the club of focal adhesion proteins

(2009) Alexander Meves et al.   TRENDS IN CELL BIOLOGY

Permissive transmembrane helix heterodimerization is required for the expression of a functional integrin

(2008) Ardcharaporn Vararattanavech et al.   BIOCHEMICAL JOURNAL

LAD-1/variant syndrome is caused by mutations inFERMT3

(2008) Taco W. Kuijpers et al.   BLOOD

SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function

(2008) Marcus Krüger et al.   CELL

Kindlin-2 controls bidirectional signaling of integrins

(2008) E. Montanez et al.   GENES & DEVELOPMENT

Disruption of the Integrin αLβ2 Transmembrane Domain Interface by β2 Thr-686 Mutation Activates αLβ2 and Promotes Micro-clustering of the αL Subunits

(2008) Ardcharaporn Vararattanavech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Migfilin, a Molecular Switch in Regulation of Integrin Activation

(2008) Sujay Subbayya Ithychanda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kindlin-2 (Mig-2): a co-activator of β3integrins

(2008) Yan-Qing Ma et al.   JOURNAL OF CELL BIOLOGY

Talin at a glance

(2008) D. R. Critchley et al.   JOURNAL OF CELL SCIENCE

Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration

(2008) Nicole A. Morin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RACK1 Regulates Directional Cell Migration by Acting on Gβγ at the Interface with Its Effectors PLCβ and PI3Kγ

(2008) Songhai Chen et al.   MOLECULAR BIOLOGY OF THE CELL

Kindlin-3 is essential for integrin activation and platelet aggregation

(2008) Markus Moser et al.   NATURE MEDICINE