Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses

The potential role of Th17 lymphocytes in patients with psoriasis

(2018) Mahnaz Mansouri et al.   ANAIS BRASILEIROS DE DERMATOLOGIA

The increased protection and pathology in Mycobacterium tuberculosis-infected IL-27R-alpha-deficient mice is supported by IL-17A and is associated with the IL-17A-induced expansion of multifunctional T cells

(2018) Hanna Erdmann et al.   Mucosal Immunology

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease

(2018) Chengxiang Qiu et al.   NATURE MEDICINE

IL-17 Receptor Signaling Negatively Regulates the Development of Tubulointerstitial Fibrosis in the Kidney

(2018) Kritika Ramani et al.   MEDIATORS OF INFLAMMATION

IL-4/IL-13–mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury

(2017) Ming-Zhi Zhang et al.   KIDNEY INTERNATIONAL

IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection

(2017) Gaia Muallem et al.   PLoS Pathogens

Human Kidney Tubule-Specific Gene Expression Based Dissection of Chronic Kidney Disease Traits

(2017) Pazit Beckerman et al.   EBioMedicine

Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target

(2017) Roberta G. Marangoni et al.   Scientific Reports

Interleukin 17 signaling drives Type I Interferon induced proliferative crescentic glomerulonephritis in lupus-prone mice

(2016) Kritika Ramani et al.   CLINICAL IMMUNOLOGY

Monocyte chemoattractant protein-1 and the kidney

(2016) Hermann Haller et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Systemic over-release of interleukin-17 in acute kidney injury after septic shock: Clinical and experimental evidence

(2016) Panagiota Maravitsa et al.   IMMUNOLOGY LETTERS

Alternatively activated macrophages determine repair of the infarcted adult murine heart

(2016) Manabu Shiraishi et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronically Elevated Levels of Short-Chain Fatty Acids Induce T Cell-Mediated Ureteritis and Hydronephrosis

(2016) J. Park et al.   JOURNAL OF IMMUNOLOGY

Low Level of Serum Interleukin 27 in Patients With Systemic Lupus Erythematosus: TABLE 1.

(2016) Ting-Ting Li et al.   JOURNAL OF INVESTIGATIVE MEDICINE

The Immunobiology of Interleukin-27

(2015) Hiroki Yoshida et al.   Annual Review of Immunology

Plasma IL-6 and IL-10 Concentrations Predict AKI and Long-Term Mortality in Adults after Cardiac Surgery

(2015) W. R. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism

(2015) Purvi Mehrotra et al.   KIDNEY INTERNATIONAL

Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: Potential role in liver fibrosis

(2015) Suneetha Amara et al.   MOLECULAR IMMUNOLOGY

Interleukin-27 and interleukin-23 in patients with systemic lupus erythematosus: possible role in lupus nephritis

(2015) LP Xia et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

The Role of M2 Macrophages in the Progression of Chronic Kidney Disease following Acute Kidney Injury

(2015) Myung-Gyu Kim et al.   PLoS One

The Role of Macrophages in the Development of Human Renal Allograft Fibrosis in the First Year After Transplantation

(2014) D. Toki et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Complement Component C5a Permits the Coexistence of Pathogenic Th17 Cells and Type I IFN in Lupus

(2014) Sudesh Pawaria et al.   JOURNAL OF IMMUNOLOGY

IL-17A produced by bothγδT and Th17 cells promotes renal fibrosis via RANTES-mediated leukocyte infiltration after renal obstruction

(2014) Xiaogang Peng et al.   JOURNAL OF PATHOLOGY

Specific Macrophage Subtypes Influence the Progression of Rhabdomyolysis-Induced Kidney Injury

(2014) J. Belliere et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines

(2014) S. Becattini et al.   SCIENCE

Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza

(2014) Francesca Diane M. Liu et al.   PLoS Pathogens

Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii

(2014) Christopher D. Dupont et al.   PLoS Pathogens

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

The Immunology of Fibrosis

(2013) Georg Wick et al.   Annual Review of Immunology

Decreased serum interleukin 27 in Brazilian systemic lupus erythematosus patients

(2013) Angela Luzia Branco Pinto Duarte et al.   MOLECULAR BIOLOGY REPORTS

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(2013) Tarcio Braga et al.   MOLECULAR MEDICINE

Gene Polymorphisms of Interleukin-17 and Interleukin-17 Receptor Are Associated with End-Stage Kidney Disease

(2012) Yang-Gyun Kim et al.   AMERICAN JOURNAL OF NEPHROLOGY

CD4+ T Lymphocytes, Especially Th2 Cells, Contribute to the Progress of Renal Fibrosis

(2012) Lili Liu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Interleukin-27 Receptor Limits Atherosclerosis in Ldlr −/− Mice

(2012) Ekaterina K. Koltsova et al.   CIRCULATION RESEARCH

Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1

(2012) Kiyoshi Hirahara et al.   IMMUNITY

Hanging in the balance: endogenous anti-inflammatory mechanisms in tissue repair and fibrosis

(2012) Amiram Ariel et al.   JOURNAL OF PATHOLOGY

The IL-27 Receptor Has Biphasic Effects in Crescentic Glomerulonephritis Mediated Through Th1 Responses

(2011) Shaun A. Summers et al.   AMERICAN JOURNAL OF PATHOLOGY

Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice

(2010) Jason C. Kovacic et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel subset of CD4+TH2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma

(2010) Yui-Hsi Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17-Mediated Monocyte Migration Occurs Partially through CC Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Induction

(2010) S. Shahrara et al.   JOURNAL OF IMMUNOLOGY

Intragraft Th17 Infiltrate Promotes Lymphoid Neogenesis and Hastens Clinical Chronic Rejection

(2010) C. Deteix et al.   JOURNAL OF IMMUNOLOGY

Heterogeneity and plasticity of T helper cells

(2009) Jinfang Zhu et al.   CELL RESEARCH

Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity

(2009) Federica Sallusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tracking the Total CD8 T Cell Response to Infection Reveals Substantial Discordance in Magnitude and Kinetics between Inbred and Outbred Hosts

(2009) D. Rai et al.   JOURNAL OF IMMUNOLOGY

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

(2009) Robert L. Chevalier et al.   KIDNEY INTERNATIONAL

Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes

(2008) Miguel Ascon et al.   KIDNEY INTERNATIONAL

Deficiency in EBV-induced gene 3 (EBI3) in MRL/lpr mice results in pathological alteration of autoimmune glomerulonephritis and sialadenitis

(2008) Takashi Igawa et al.   Modern Rheumatology

Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor   (WSX-1)

(2007) N Sugiyama et al.   ANNALS OF THE RHEUMATIC DISEASES