Transcriptomic characterization of microglia activation in a rat model of ischemic stroke

Microglia mediate forgetting via complement-dependent synaptic elimination

(2020) Chao Wang et al.   SCIENCE

Microglia Heterogeneity in the Single-Cell Era

(2020) Takahiro Masuda et al.   Cell Reports

Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain

(2020) Ranjie Xu et al.   Nature Communications

Neuroimmune crosstalk in the pathophysiology of hypertension

(2019) Laura Calvillo et al.   Nature Reviews Cardiology

Distinct Metabolic Patterns During Microglial Remodeling by Oleate and Palmitate

(2019) Bruno Chausse et al.   BIOSCIENCE REPORTS

Linoleic acid rescues microglia inflammation triggered by saturated fatty acid

(2019) Thai Hien Tu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Microglial activation after ischaemic stroke

(2019) Shengxiang Zhang   JOURNAL OF INVESTIGATIVE MEDICINE

Neuroprotective effects of oleic acid in rodent models of cerebral ischaemia

(2019) Jungbin Song et al.   Scientific Reports

Omega-3 polyunsaturated fatty acid attenuates the inflammatory response by modulating microglia polarization through SIRT1-mediated deacetylation of the HMGB1/NF-κB pathway following experimental traumatic brain injury

(2018) Xiangrong Chen et al.   Journal of Neuroinflammation

Microglial immune checkpoint mechanisms

(2018) Aleksandra Deczkowska et al.   NATURE NEUROSCIENCE

Early minor stimulation of microglial TLR2 and TLR4 receptors attenuates Alzheimer's disease–related cognitive deficit in rats: behavioral, molecular, and electrophysiological evidence

(2018) Hamid Gholami Pourbadie et al.   NEUROBIOLOGY OF AGING

Different Effects of Normobaric Oxygen in Normotensive Versus Hypertensive Rats After Focal Cerebral Ischemia

(2018) Jing Lan et al.   STROKE

Microglia heterogeneity along a spatio-temporal axis: More questions than answers

(2018) Aymeric Silvin et al.   GLIA

The importance of comorbidities in ischemic stroke: Impact of hypertension on the cerebral circulation

(2018) Marilyn J Cipolla et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of β-amyloid

(2018) Ana Rubio-Araiz et al.   Journal of Neuroinflammation

Silencing of TGFβ signalling in microglia results in impaired homeostasis

(2018) Tanja Zöller et al.   Nature Communications

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

(2018) Qingyun Li et al.   NEURON

Role of Microglia TLRs in Neurodegeneration

(2018) Bernd L. Fiebich et al.   Frontiers in Cellular Neuroscience

The biphasic function of microglia in ischemic stroke

(2017) Yuanyuan Ma et al.   PROGRESS IN NEUROBIOLOGY

Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer’s disease

(2016) Claire L. McDonald et al.   BRAIN BEHAVIOR AND IMMUNITY

An atypical role for the myeloid receptor Mincle in central nervous system injury

(2016) Thiruma V Arumugam et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential subnetwork of chemokines/cytokines in human, mouse, and rat brain cells after oxygen–glucose deprivation

(2016) Yang Du et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells

(2016) Luke M. Healy et al.   JOURNAL OF IMMUNOLOGY

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

A Post-stroke Therapeutic Regimen with Omega-3 Polyunsaturated Fatty Acids that Promotes White Matter Integrity and Beneficial Microglial Responses after Cerebral Ischemia

(2016) Xiaoyan Jiang et al.   Translational Stroke Research

α-TLR2 antibody attenuates the Aβ-mediated inflammatory response in microglia through enhanced expression of SIGIRR

(2015) Derek A. Costello et al.   BRAIN BEHAVIOR AND IMMUNITY

MicroRNA-181c negatively regulates the inflammatory response in oxygen-glucose-deprived microglia by targeting Toll-like receptor 4

(2015) Li Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

(2014) Marco Prinz et al.   NATURE REVIEWS NEUROSCIENCE

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

A Decade of Research on TLR2 Discovering Its Pivotal Role in Glial Activation and Neuroinflammation in Neurodegenerative Diseases

(2014) Jin Hee Hayward et al.   Experimental Neurobiology

From development to dysfunction: Microglia and the complement cascade in CNS homeostasis

(2013) Matthew K. Zabel et al.   AGEING RESEARCH REVIEWS

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Exposure to the Saturated Free Fatty Acid Palmitate Alters BV-2 Microglia Inflammatory Response

(2013) Linda M. Tracy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Activity-Dependent Neural Plasticity from Bench to Bedside

(2013) Karunesh Ganguly et al.   NEURON

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS

(2012) Oleg Butovsky et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling

(2011) Zhen Wang et al.   BRITISH JOURNAL OF NUTRITION

The central nervous system and inflammation in hypertension

(2011) Paul J Marvar et al.   CURRENT OPINION IN PHARMACOLOGY

The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Omega-3 Polyunsaturated Fatty Acid Supplementation Confers Long-Term Neuroprotection Against Neonatal Hypoxic–Ischemic Brain Injury Through Anti-Inflammatory Actions

(2010) Wenting Zhang et al.   STROKE

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Can the immune system be harnessed to repair the CNS?

(2008) Phillip G. Popovich et al.   NATURE REVIEWS NEUROSCIENCE

Neuroglia: the 150 years after

(2008) Helmut Kettenmann et al.   TRENDS IN NEUROSCIENCES