Omega-3 polyunsaturated fatty acid attenuates the inflammatory response by modulating microglia polarization through SIRT1-mediated deacetylation of the HMGB1/NF-κB pathway following experimental traumatic brain injury

Isoliquiritigenin inhibits TNF-α-induced release of high-mobility group box 1 through activation of HDAC in human intestinal epithelial HT-29 cells

(2017) Jin-Hua Chi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Histone deacetylase-high mobility group box-1 pathway targeted by hypaconitine suppresses the apoptosis of endothelial cells

(2017) Ye Bai et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Omega-3 polyunsaturated fatty acids alleviate hepatic steatosis-induced inflammation through Sirt1-mediated nuclear translocation of NF-κB p65 subunit in hepatocytes of large yellow croaker ( Larmichthys crocea )

(2017) Tianjiao Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Progesterone therapy induces an M1 to M2 switch in microglia phenotype and suppresses NLRP3 inflammasome in a cuprizone-induced demyelination mouse model

(2017) Roya Aryanpour et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TLR4 signal ablation attenuated neurological deficits by regulating microglial M1/M2 phenotype after traumatic brain injury in mice

(2017) Xiaolong Yao et al.   JOURNAL OF NEUROIMMUNOLOGY

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

(2017) Sarah Hopp et al.   Journal of Neuroinflammation

Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury

(2017) Alok Kumar et al.   Journal of Neuroinflammation

Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury

(2017) Xiangrong Chen et al.   Journal of Neuroinflammation

Photobiomodulation for traumatic brain injury and stroke

(2017) Michael R. Hamblin   JOURNAL OF NEUROSCIENCE RESEARCH

Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats

(2017) Dengli Wang et al.   Scientific Reports

Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-κB and HMGB1 pathways through the upregulation of SIRT1

(2017) Kuo-Cheng Lan et al.   Scientific Reports

The danger zone: Systematic review of the role of HMGB1 danger signalling in traumatic brain injury

(2016) Taylor M. Parker et al.   BRAIN INJURY

High-mobility group box-B1 (HMGB1) mediates the hypoxia-induced mesenchymal transition of osteoblast cells via activating ERK/JNK signaling

(2016) Yiyan Qiu et al.   CELL BIOLOGY INTERNATIONAL

Reduction of Oxidative/Nitrosative Stress in Brain and its Involvement in the Neuroprotective Effect of n-3 PUFA in Alzheimer's Disease

(2016) Simona Serini et al.   Current Alzheimer Research

Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation

(2016) Niek GJ Leus et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Ethyl pyruvate inhibits the acetylation and release of HMGB1 via effects on SIRT1/STAT signaling in LPS-activated RAW264.7 cells and peritoneal macrophages

(2016) Young Min Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Prognostic value of HMGB1 and oxidative stress markers in multiple trauma patients: A single-centre prospective study

(2016) Francesca Polito et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Emerging role of HMGB1 in lung diseases: friend or foe

(2016) Junying Ding et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

HMGB1 Inhibits Apoptosis Following MI and Induces Autophagy via mTORC1 Inhibition

(2016) Eleonora Foglio et al.   JOURNAL OF CELLULAR PHYSIOLOGY

High-mobility group box 1 is an important mediator of microglial activation induced by cortical spreading depression

(2016) Tsubasa Takizawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury

(2016) Alok Kumar et al.   JOURNAL OF NEUROTRAUMA

LPS Pretreatment Provides Neuroprotective Roles in Rats with Subarachnoid Hemorrhage by Downregulating MMP9 and Caspase3 Associated with TLR4 Signaling Activation

(2016) Ting-Hua Wang et al.   MOLECULAR NEUROBIOLOGY

Progranulin Protects Hippocampal Neurogenesis via Suppression of Neuroinflammatory Responses Under Acute Immune Stress

(2016) Yanbo Ma et al.   MOLECULAR NEUROBIOLOGY

Maternal Omega-3 Supplement Improves Dopaminergic System in Pre- and Postnatal Inflammation-Induced Neurotoxicity in Parkinson’s Disease Model

(2016) Ana Marcia Delattre et al.   MOLECULAR NEUROBIOLOGY

Downregulation of NAD-Dependent Deacetylase SIRT2 Protects Mouse Brain Against Ischemic Stroke

(2016) Xiao Qiang Xie et al.   MOLECULAR NEUROBIOLOGY

The combination of vitamins and omega-3 fatty acids has an enhanced anti-inflammatory effect on microglia

(2016) E. Kurtys et al.   NEUROCHEMISTRY INTERNATIONAL

Effects of ω-3 fatty acids on toll-like receptor 4 and nuclear factor-κB p56 in lungs of rats with severe acute pancreatitis

(2016) Bin Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats

(2016) Xiang-Sheng Zhang et al.   Cell Death & Disease

Administration of DHA Reduces Endoplasmic Reticulum Stress-Associated Inflammation and Alters Microglial or Macrophage Activation in Traumatic Brain Injury

(2015) Lloyd D. Harvey et al.   ASN Neuro

NAD+/NADH Metabolism and NAD+-Dependent Enzymes in Cell Death and Ischemic Brain Injury: Current Advances and Therapeutic Implications

(2015) Yingxin Ma et al.   CURRENT MEDICINAL CHEMISTRY

SIRT1 and Neural Cell Fate Determination

(2015) Yulong Cai et al.   MOLECULAR NEUROBIOLOGY

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis

(2015) Guohua Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Sirt1 During the Ageing Process: Relevance to Protection of Synapses in the Brain

(2014) Juan A. Godoy et al.   MOLECULAR NEUROBIOLOGY

Phagocytosis of Microglia in the Central Nervous System Diseases

(2014) Ruying Fu et al.   MOLECULAR NEUROBIOLOGY

Release of Neuronal HMGB1 by Ethanol through Decreased HDAC Activity Activates Brain Neuroimmune Signaling

(2014) Jian Y. Zou et al.   PLoS One

High mobility group box protein-1 promotes cerebral edema after traumatic brain injury via activation of toll-like receptor 4

(2013) Melissa D. Laird et al.   GLIA

Omega-3 Polyunsaturated Fatty Acid Supplementation Improves Neurologic Recovery and Attenuates White Matter Injury after Experimental Traumatic Brain Injury

(2013) Hongjian Pu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats

(2013) Cheng-Yi Chang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Sirtuin activators and inhibitors

(2012) José M. Villalba et al.   BIOFACTORS

HMGB1 in Development and Diseases of the Central Nervous System

(2012) Ping Fang et al.   MOLECULAR NEUROBIOLOGY