MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells

Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status

(2015) C. T. Cummings et al.   MOLECULAR CANCER THERAPEUTICS

Ontogeny and Functions of Central Nervous System Macrophages

(2014) Atsuko Katsumoto et al.   JOURNAL OF IMMUNOLOGY

UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor

(2014) Weihe Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeted GAS6 Delivery to the CNS Protects Axons from Damage during Experimental Autoimmune Encephalomyelitis

(2014) Ross C. Gruber et al.   JOURNAL OF NEUROSCIENCE

Multiple sclerosis genetics

(2014) Stephen Sawcer et al.   LANCET NEUROLOGY

Diversification of TAM receptor tyrosine kinase function

(2014) Anna Zagórska et al.   NATURE IMMUNOLOGY

A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

(2013) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

UNC1062, a new and potent Mer inhibitor

(2013) Jing Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Selective Upregulation of Scavenger Receptors in and Around Demyelinating Areas in Multiple Sclerosis

(2013) Debbie A.E. Hendrickx et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Biology of the TAM Receptors

(2013) G. Lemke   Cold Spring Harbor Perspectives in Biology

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Identification of a microglia phenotype supportive of remyelination

(2011) Marta Olah et al.   GLIA

Myelin ingestion alters macrophage antigen-presenting function in vitro and in vivo

(2011) M. van Zwam et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes

(2011) Miri Gitik et al.   Journal of Neuroinflammation

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

(2011) Jason G Weinger et al.   Journal of Neuroinflammation

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

TAM receptors and the clearance of apoptotic cells

(2010) Greg Lemke et al.   Annals of the New York Academy of Sciences

Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums

(2010) Kodi S. Ravichandran   JOURNAL OF EXPERIMENTAL MEDICINE

GAS6 Enhances Repair Following Cuprizone-Induced Demyelination

(2010) Vladislav Tsiperson et al.   PLoS One

TAM Receptor Signalling and Demyelination

(2009) Michele D. Binder et al.   NEUROSIGNALS

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

Gas6 Deficiency Increases Oligodendrocyte Loss and Microglial Activation in Response to Cuprizone-Induced Demyelination

(2008) M. D. Binder et al.   JOURNAL OF NEUROSCIENCE