Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

Divergent Modulation of Src-Family Kinase Regulatory Interactions with ATP-Competitive Inhibitors

(2014) Stephen E. Leonard et al.   ACS Chemical Biology

Structural Insight into How Streptomyces coelicolor Maltosyl Transferase GlgE Binds α-Maltose 1-Phosphate and Forms a Maltosyl-enzyme Intermediate

(2014) Karl Syson et al.   BIOCHEMISTRY

Synthesis of a C-phosphonate mimic of maltose-1-phosphate and inhibition studies on Mycobacterium tuberculosis GlgE

(2014) Sri Kumar Veleti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Two newly identified sites in the N-terminal regulatory domain of Aurora-A are essential for auto-inhibition

(2014) Meirong Bai et al.   BIOTECHNOLOGY LETTERS

The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies

(2014) A. Nobre et al.   MICROBIOLOGY-SGM

Homotypic dimerization of a maltose kinase for molecular scaffolding

(2014) Jun Li et al.   Scientific Reports

Synthesis of α-Glucan in Mycobacteria Involves a Hetero-octameric Complex of Trehalose Synthase TreS and Maltokinase Pep2

(2013) Rana Roy et al.   ACS Chemical Biology

Flux through Trehalose Synthase Flows from Trehalose to the Alpha Anomer of Maltose in Mycobacteria

(2013) Farzana Miah et al.   CHEMISTRY & BIOLOGY

The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode

(2013) S. Caner et al.   GLYCOBIOLOGY

Reinterpreting the Action of ATP Analogs on KATPChannels

(2013) David Ortiz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2″-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases

(2012) Kun Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry

(2012) Benjamin M. Swarts et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biosynthesis of mycobacterial methylglucose lipopolysaccharides

(2012) Vitor Mendes et al.   NATURAL PRODUCT REPORTS

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ProtTest 3: fast selection of best-fit models of protein evolution

(2011) Diego Darriba et al.   BIOINFORMATICS

Structure ofStreptomycesMaltosyltransferase GlgE, a Homologue of a Genetically Validated Anti-tuberculosis Target

(2011) Karl Syson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unexpected and widespread connections between bacterial glycogen and trehalose metabolism

(2011) G. Chandra et al.   MICROBIOLOGY-SGM

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Experimental phasing withSHELXC/D/E: combining chain tracing with density modification

(2010) George M. Sheldrick   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Biochemical characterization of the maltokinase from Mycobacterium bovis BCG

(2010) Vítor Mendes et al.   BMC BIOCHEMISTRY

The significance of GlgE as a new target for tuberculosis

(2010) W.R.Jr. Jacobs et al.   DRUG NEWS & PERSPECTIVES

Mycobacterium leprae: genes, pseudogenes and genetic diversity

(2010) Pushpendra Singh et al.   Future Microbiology

Crystal Structure of Full-lengthMycobacterium tuberculosisH37Rv Glycogen Branching Enzyme

(2010) Kuntal Pal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Last Step in the Conversion of Trehalose to Glycogen

(2010) Alan D. Elbein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity

(2010) Nuno Empadinhas et al.   MOLECULAR MICROBIOLOGY

Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway

(2010) Rainer Kalscheuer et al.   Nature Chemical Biology

Fpocket: An open source platform for ligand pocket detection

(2009) Vincent Le Guilloux et al.   BMC BIOINFORMATICS

The Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2''-Phosphotransferase-IIa [APH(2'')-IIa] Provide Insights into Substrate Selectivity in the APH(2'') Subfamily

(2009) P. G. Young et al.   JOURNAL OF BACTERIOLOGY

A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea

(2009) Dongying Wu et al.   NATURE

Characterization of Solanum tuberosum Multicystatin and Its Structural comparison with Other Cystatins

(2009) M. S. Nissen et al.   PLANT CELL

Non Mycobacterial Virulence Genes in the Genome of the Emerging Pathogen Mycobacterium abscessus

(2009) Fabienne Ripoll et al.   PLoS One

Trehalose synthase converts glycogen to trehalose

(2008) Yuan-Tseng Pan et al.   FEBS Journal

Cystatins: Biochemical and structural properties, and medical relevance

(2008) ">Vito Turk   Frontiers in Bioscience-Landmark

Capsular glucan and intracellular glycogen ofMycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

(2008) Tounkang Sambou et al.   MOLECULAR MICROBIOLOGY

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

Mycobacterium tuberculosis Glucosyl-3-Phosphoglycerate Synthase: Structure of a Key Enzyme in Methylglucose Lipopolysaccharide Biosynthesis

(2008) Pedro José Barbosa Pereira et al.   PLoS One