Enforced C-Src Activation Causes Compartmental Dysregulation of PI3K and PTEN Molecules in Lipid Rafts of Tongue Squamous Carcinoma Cells by Attenuating Rac1-Akt-GLUT-1-Mediated Sphingolipid Synthesis

Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy

(2020) Faustino Mollinedo et al.   JOURNAL OF LIPID RESEARCH

Impairment of Membrane Lipid Homeostasis by Bichalcone Analog TSWU-BR4 Attenuates Function of GRP78 in Regulation of the Oxidative Balance and Invasion of Cancer Cells

(2020) Tsung-Lin Lee et al.   Cells

High USP6NL levels in breast cancer sustain chronic AKT phosphorylation and GLUT1 stability fueling aerobic glycolysis

(2018) Daniele Avanzato et al.   CANCER RESEARCH

Compartmentalisation of RAC1 signalling

(2018) Aishwarya Payapilly et al.   CURRENT OPINION IN CELL BIOLOGY

Gallic acid inhibits bladder cancer cell proliferation and migration via regulating fatty acid synthase (FAS)

(2018) Chung-Chia Liao et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

De Novo Fatty Acid Synthesis Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer

(2018) Naser Jafari et al.   MOLECULAR CANCER RESEARCH

Perturbing the Dynamics and Organization of Cell Membrane Components: A New Paradigm for Cancer-Targeted Therapies

(2018) Nuno Bernardes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis

(2017) Jia Zhang et al.   Nature Communications

Activation of Casein Kinase II by Gallic Acid Induces BIK–BAX/BAK-Mediated ER Ca++-ROS-Dependent Apoptosis of Human Oral Cancer Cells

(2017) Meng-Liang Lin et al.   Frontiers in Physiology

Oncogenic activation of the PI3K/Akt pathway promotes cellular glucose uptake by downregulating the expression of thioredoxin-interacting protein

(2016) Shin Yee Hong et al.   CELLULAR SIGNALLING

Suppression of phospho-p85α-GTP-Rac1 lipid raft interaction by bichalcone analog attenuates cancer cell invasion

(2016) Hui-Li Lu et al.   MOLECULAR CARCINOGENESIS

Lipid metabolic reprogramming in cancer cells

(2016) S Beloribi-Djefaflia et al.   Oncogenesis

Changes in membrane sphingolipid composition modulate dynamics and adhesion of integrin nanoclusters

(2016) Christina Eich et al.   Scientific Reports

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

(2015) Hideki Makinoshima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the PI3K pathway through a p85α monomer–homodimer equilibrium

(2015) Lydia WT Cheung et al.   eLife

Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype

(2014) Zunling Li et al.   BMC CANCER

Human Protein Kinase CK2 Phosphorylates Matrix Metalloproteinase 2 and Inhibits its Activity

(2014) Kamila Filipiak et al.   CHEMBIOCHEM

Glucose Availability and Glycolytic Metabolism Dictate Glycosphingolipid Levels

(2014) Morgan Stathem et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells

(2012) Meng-Liang Lin et al.   MOLECULAR CARCINOGENESIS

CK2 functionally interacts with AKT/PKB to promote the β-catenin-dependent expression of survivin and enhance cell survival

(2011) Daniela P. Ponce et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains

(2011) X. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of β-catenin transcriptional activity

(2010) Daniela P. Ponce et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Membranes in Balance: Mechanisms of Sphingolipid Homeostasis

(2010) David K. Breslow et al.   MOLECULAR CELL

Protein Kinase CK2 in Health and Disease

(2009) J. H. Trembley et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

CK2 Is a Novel Negative Regulator of NADPH Oxidase and a Neuroprotectant in Mice after Cerebral Ischemia

(2009) G. S. Kim et al.   JOURNAL OF NEUROSCIENCE

Phosphatidylinositol 3-Kinase/AKT Pathway Regulates the Endoplasmic Reticulum to Golgi Traffic of Ceramide in Glioma Cells

(2008) Paola Giussani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY