Intestinal Macrophages at the Crossroad between Diet, Inflammation, and Cancer

Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

(2020) Tarini Shankar Ghosh et al.   GUT

Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake

(2020) Victoria Meslier et al.   GUT

Head-to-head trials in inflammatory bowel disease: past, present and future

(2020) Lieven Pouillon et al.   Nature Reviews Gastroenterology & Hepatology

Functions of Macrophages in the Maintenance of Intestinal Homeostasis

(2019) Shuai Wang et al.   Journal of Immunology Research

Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them

(2019) M. A. F. Yahaya et al.   Journal of Immunology Research

Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2

(2019) Lei Zhou et al.   NATURE

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

(2019) Andrew Maltez Thomas et al.   NATURE MEDICINE

Macrophages in Colorectal Cancer Liver Metastases

(2019) Nina Cortese et al.   Cancers

Fusobacterium nucleatum tumor DNA levels are associated with survival in colorectal cancer patients

(2019) Andrew T. Kunzmann et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD

(2019) Yi Rang Na et al.   Nature Reviews Gastroenterology & Hepatology

Gut Microbiota Shapes the Efficiency of Cancer Therapy

(2019) Weidong Ma et al.   Frontiers in Microbiology

IL-23–producing IL-10Rα–deficient gut macrophages elicit an IL-22–driven proinflammatory epithelial cell response

(2019) Biana Bernshtein et al.   Science Immunology

Diversity, Mechanisms, and Significance of Macrophage Plasticity

(2019) Massimo Locati et al.   Annual Review of Pathology-Mechanisms of Disease

The Immunoscore: Colon Cancer and Beyond

(2019) Helen K Angell et al.   CLINICAL CANCER RESEARCH

The Two Faces of Tumor-Associated Macrophages and Their Clinical Significance in Colorectal Cancer

(2019) Marta L. Pinto et al.   Frontiers in Immunology

Myeloid immunosuppression and immune checkpoints in the tumor microenvironment

(2019) Kyohei Nakamura et al.   Cellular & Molecular Immunology

Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer

(2019) Mingyang Song et al.   GASTROENTEROLOGY

Western Diet and the Immune System: An Inflammatory Connection

(2019) Anette Christ et al.   IMMUNITY

Quercetin Exposure Suppresses the Inflammatory Pathway in Intestinal Organoids from Winnie Mice

(2019) Manuela Dicarlo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages

(2019) Zhipeng Liu et al.   CANCER LETTERS

Gut macrophages: key players in intestinal immunity and tissue physiology

(2019) Paul A. Muller et al.   CURRENT OPINION IN IMMUNOLOGY

The Intestinal Microbiota in Colorectal Cancer

(2018) Herbert Tilg et al.   CANCER CELL

Myeloid cell heterogeneity in cancer: not a single cell alike

(2018) Mate Kiss et al.   CELLULAR IMMUNOLOGY

Critical Role for the Microbiota in CX 3 CR1 + Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses

(2018) Myunghoo Kim et al.   IMMUNITY

Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression

(2018) Tovah N. Shaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human intestinal pro-inflammatory CD11chighCCR2+CX3CR1+ macrophages, but not their tolerogenic CD11c−CCR2−CX3CR1− counterparts, are expanded in inflammatory bowel disease

(2018) D. Bernardo et al.   Mucosal Immunology

CX3CR1+mononuclear phagocytes control immunity to intestinal fungi

(2018) Irina Leonardi et al.   SCIENCE

Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment

(2018) Claudia M. Wunderlich et al.   Nature Communications

The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche

(2018) Anuj Sehgal et al.   Nature Communications

Butyrate: A Double-Edged Sword for Health?

(2018) Hu Liu et al.   Advances in Nutrition

Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers

(2018) Zhenwei Dai et al.   Microbiome

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

(2018) Sebastiaan De Schepper et al.   CELL

Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer

(2018) Julie G Grossman et al.   OncoImmunology

Dietary phytochemicals in colorectal cancer prevention and treatment: A focus on the molecular mechanisms involved

(2018) Sadia Afrin et al.   BIOTECHNOLOGY ADVANCES

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis

(2018) Nicholas A. Scott et al.   Science Translational Medicine

Origin, Differentiation, and Function of Intestinal Macrophages

(2018) Calum C. Bain et al.   Frontiers in Immunology

The delicate balance of macrophages in colorectal cancer; their role in tumour development and therapeutic potential

(2017) R. Braster et al.   IMMUNOBIOLOGY

Non-redundant role of the chemokine receptor CX3CR1 in the anti-inflammatory function of gut macrophages

(2017) G. Marelli et al.   IMMUNOBIOLOGY

Transcriptional and functional profiling defines human small intestinal macrophage subsets

(2017) Anna Bujko et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling

(2017) A Schridde et al.   Mucosal Immunology

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Protectin D1n-3 DPAand resolvin D5n-3 DPAare effectors of intestinal protection

(2017) Thomas Gobbetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting tumor associated macrophages: The new challenge for nanomedicine

(2017) Fernando Torres Andón et al.   SEMINARS IN IMMUNOLOGY

Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner

(2017) Troy D. Hubbard et al.   Journal of Functional Foods

Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages

(2017) Pengfei Sun et al.   Oncotarget

Linking Gut Microbiota to Colorectal Cancer

(2017) Hans Raskov et al.   Journal of Cancer

CD169 Expressing Macrophage, a Key Subset in Mesenteric Lymph Nodes Promotes Mucosal Inflammation in Dextran Sulfate Sodium-Induced Colitis

(2017) Qiuting Li et al.   Frontiers in Immunology

Pro-Resolving Mediators in Regulating and Conferring Macrophage Function

(2017) Jesmond Dalli et al.   Frontiers in Immunology

The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces

(2017) Donjete Statovci et al.   Frontiers in Immunology

Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer

(2017) Alberto Malesci et al.   OncoImmunology

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

(2016) Niels Halama et al.   CANCER CELL

Macrophages induce resistance to 5-fluorouracil chemotherapy in colorectal cancer through the release of putrescine

(2016) Xuan Zhang et al.   CANCER LETTERS

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer

(2016) Maria Rosaria Galdiero et al.   INTERNATIONAL JOURNAL OF CANCER

EGFR regulates macrophage activation and function in bacterial infection

(2016) Dana M. Hardbower et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor macrophages are pivotal constructors of tumor collagenous matrix

(2016) Ran Afik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PKA regulatory IIα subunit is essential for PGD 2 -mediated resolution of inflammation

(2016) Deping Kong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CX3CR1+Cell–MediatedSalmonellaExclusion Protects the Intestinal Mucosa during the Initial Stage of Infection

(2016) Angela L. Man et al.   JOURNAL OF IMMUNOLOGY

Different tissue phagocytes sample apoptotic cells to direct distinct homeostasis programs

(2016) Ryan J. Cummings et al.   NATURE

Food, nutrients and nutraceuticals affecting the course of inflammatory bowel disease

(2016) José Antonio Uranga et al.   Pharmacological Reports

Reduced numbers of mucosal DRintmacrophages and increased numbers of CD103+dendritic cells during anti-TNF-α treatment in patients with Crohn’s disease

(2016) Anders Dige et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Metabolic Inflammation-Differential Modulation by Dietary Constituents

(2016) Claire Lyons et al.   Nutrients

IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine

(2016) Mathilde J.H. Girard-Madoux et al.   Oncotarget

Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer

(2016) Yoonjin Kwak et al.   Oncotarget

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine

(2016) Takanori Ochi et al.   Scientific Reports

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Micronutrient deficiencies in inflammatory bowel disease

(2015) Roni Weisshof et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Nutrients, Foods, and Colorectal Cancer Prevention

(2015) Mingyang Song et al.   GASTROENTEROLOGY

Vitamin A-Deficient Hosts Become Nonsymptomatic Reservoirs of Escherichia coli-Like Enteric Infections

(2015) Kaitlin L. McDaniel et al.   INFECTION AND IMMUNITY

Vitamin K deficiency leads to exacerbation of murine dextran sulfate sodium-induced colitis

(2015) Eri Shiraishi et al.   JOURNAL OF GASTROENTEROLOGY

Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut

(2015) Andrea Michielan et al.   MEDIATORS OF INFLAMMATION

β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon

(2015) A Schippers et al.   Mucosal Immunology

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

(2015) L A Borthwick et al.   Mucosal Immunology

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

(2015) Kenichi Asano et al.   Nature Communications

Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study

(2014) S. Bae et al.   CANCER RESEARCH

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

The Bacteroides fragilis Toxin Gene Is Prevalent in the Colon Mucosa of Colorectal Cancer Patients

(2014) Annemarie Boleij et al.   CLINICAL INFECTIOUS DISEASES

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

(2014) Dror S. Shouval et al.   IMMUNITY

Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis

(2014) Ehud Zigmond et al.   IMMUNITY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Macrophages in intestinal homeostasis and inflammation

(2014) Calum C. Bain et al.   IMMUNOLOGICAL REVIEWS

Macrophage heterogeneity in tissues: phenotypic diversity and functions

(2014) Siamon Gordon et al.   IMMUNOLOGICAL REVIEWS

CX3CR1+mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22

(2014) Randy S. Longman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Intestinal Macrophage/Epithelial Cell-Derived CCL11/Eotaxin-1 Mediates Eosinophil Recruitment and Function in Pediatric Ulcerative Colitis

(2014) R. Ahrens et al.   JOURNAL OF IMMUNOLOGY

Dynamic Changes in Macrophage Activation and Proliferation during the Development and Resolution of Intestinal Inflammation

(2014) Matthew C. Little et al.   JOURNAL OF IMMUNOLOGY

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Mediterranean dietary pattern, inflammation and endothelial function: A systematic review and meta-analysis of intervention trials

(2014) L. Schwingshackl et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

(2014) A. Mortha et al.   SCIENCE

Macrophage Regulation of Tumor Responses to Anticancer Therapies

(2013) Michele De Palma et al.   CANCER CELL

A Single Strain of Clostridium butyricum Induces Intestinal IL-10-Producing Macrophages to Suppress Acute Experimental Colitis in Mice

(2013) Atsushi Hayashi et al.   Cell Host & Microbe

Colonic bacterial metabolites and human health

(2013) Wendy R Russell et al.   CURRENT OPINION IN MICROBIOLOGY

Linking inflammation to tumorigenesis in a mouse model of high-fat-diet-enhanced colon cancer

(2013) Stani D. Day et al.   CYTOKINE

The immune cells in adipose tissue

(2013) A. W. Ferrante   DIABETES OBESITY & METABOLISM

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

(2013) Robert H. Oakley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis

(2013) Weicheng Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

CD14hi HLA-DRdim macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohnˈs disease

(2013) Susanne Thiesen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vitamin D Regulates the Gut Microbiome and Protects Mice from Dextran Sodium Sulfate–Induced Colitis

(2013) Jot Hui Ooi et al.   JOURNAL OF NUTRITION

Human Gut Microbiome and Risk for Colorectal Cancer

(2013) Jiyoung Ahn et al.   JNCI-Journal of the National Cancer Institute

Role of Regulatory T Cells in Pathogenesis and Biological Therapy of Multiple Sclerosis

(2013) Milan Buc   MEDIATORS OF INFLAMMATION

Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection

(2013) John R Grainger et al.   NATURE MEDICINE

Active vitamin D (1,25-dihydroxyvitamin D3) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses

(2012) Natasha R. Ryz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia

(2012) Ana Paula Boroni Moreira et al.   BRITISH JOURNAL OF NUTRITION

Serum levels and mesenteric fat tissue expression of adiponectin and leptin in patients with Crohn's disease

(2012) V. S. Rodrigues et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Susceptibility and immunity to helminth parasites

(2012) Rick M Maizels et al.   CURRENT OPINION IN IMMUNOLOGY

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

What is “physiological” intestinal inflammation and how does it differ from “pathological” inflammation?

(2012) Claudio Fiocchi   INFLAMMATORY BOWEL DISEASES

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Vitamin D Inhibits Monocyte/Macrophage Proinflammatory Cytokine Production by Targeting MAPK Phosphatase-1

(2012) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium

(2012) C Manta et al.   Mucosal Immunology

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Dietary Fibre Intake and Risks of Cancers of the Colon and Rectum in the European Prospective Investigation into Cancer and Nutrition (EPIC)

(2012) Neil Murphy et al.   PLoS One

Helminthic therapy: improving mucosal barrier function

(2012) Martin J. Wolff et al.   TRENDS IN PARASITOLOGY

Large procyanidins prevent bile-acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells

(2011) Mathieu Da Silva et al.   FREE RADICAL BIOLOGY AND MEDICINE

Guidelines for the management of inflammatory bowel disease in adults

(2011) C. Mowat et al.   GUT

Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro

(2011) Anne Christine W. Vos et al.   INFLAMMATORY BOWEL DISEASES

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

(2011) Oscar Medina-Contreras et al.   JOURNAL OF CLINICAL INVESTIGATION

Colonic Eosinophilic Inflammation in Experimental Colitis Is Mediated by Ly6Chigh CCR2+ Inflammatory Monocyte/Macrophage-Derived CCL11

(2011) A. Waddell et al.   JOURNAL OF IMMUNOLOGY

Omega-3 Fatty Acid-Derived Mediators 17(R)-Hydroxy Docosahexaenoic Acid, Aspirin-Triggered Resolvin D1 and Resolvin D2 Prevent Experimental Colitis in Mice

(2011) A. F. Bento et al.   JOURNAL OF IMMUNOLOGY

Oral administration of sodium butyrate attenuates inflammation and mucosal lesion in experimental acute ulcerative colitis

(2011) Erica L.M. Vieira et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Changes in Diet and Lifestyle and Long-Term Weight Gain in Women and Men

(2011) Dariush Mozaffarian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quercetin's Effects on Intestinal Polyp Multiplicity and Macrophage Number in the ApcMin/+ Mouse

(2011) E. Angela Murphy et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris

(2011) R. BOWCUTT et al.   PARASITE IMMUNOLOGY

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

(2011) M. Fabri et al.   Science Translational Medicine

Induction of Treg cells in the mouse colonic mucosa: A central mechanism to maintain host–microbiota homeostasis

(2011) Takeshi Tanoue et al.   SEMINARS IN IMMUNOLOGY

Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance

(2011) Takatoshi Chinen et al.   Nature Communications

Evolution of Th2 Immunity: A Rapid Repair Response to Tissue Destructive Pathogens

(2011) Judith E. Allen et al.   PLoS Pathogens

Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10

(2010) Yoshiyasu Ueda et al.   INTERNATIONAL IMMUNOLOGY

Monocyte Chemoattractant Protein-1 Contributes to Gut Homeostasis and Intestinal Inflammation by Composition of IL-10–Producing Regulatory Macrophage Subset

(2010) Yasuhiro Takada et al.   JOURNAL OF IMMUNOLOGY

An Independent Subset of TLR Expressing CCR2-Dependent Macrophages Promotes Colonic Inflammation

(2010) A. M. Platt et al.   JOURNAL OF IMMUNOLOGY

Enteric Flora Expands Gut Lamina Propria CX 3 CR1 + Dendritic Cells Supporting Inflammatory Immune Responses under Normal and Inflammatory Conditions

(2010) Jan Hendrik Niess et al.   JOURNAL OF IMMUNOLOGY

Intratumoral macrophage counts correlate with tumor progression in colorectal cancer

(2010) Jung-Cheng Kang et al.   JOURNAL OF SURGICAL ONCOLOGY

The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer

(2010) Qiang Zhou et al.   Journal of Translational Medicine

Intestinal macrophages and response to microbial encroachment

(2010) P D Smith et al.   Mucosal Immunology

Diet, gut microbiota and immune responses

(2010) Kendle M Maslowski et al.   NATURE IMMUNOLOGY

A pro-resolution mediator, prostaglandin D2, is specifically up-regulated in individuals in long-term remission from ulcerative colitis

(2010) L. Vong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis

(2009) Lin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Comparison of gene expression profiles between human and mouse monocyte subsets

(2009) M. A. Ingersoll et al.   BLOOD

All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis

(2009) Aiping Bai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CD3+ cells at the invasive margin of deeply invading (pT3–T4) colorectal cancer and risk of post-surgical metastasis: a longitudinal study

(2009) Luigi Laghi et al.   LANCET ONCOLOGY

CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis

(2008) L. A. Truman et al.   BLOOD

Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a “come-and-get-me” signal

(2008) David R. Gude et al.   FASEB JOURNAL

Dietary Histidine Ameliorates Murine Colitis by Inhibition of Proinflammatory Cytokine Production From Macrophages

(2008) Ayatoshi Andou et al.   GASTROENTEROLOGY

Gr1+ Inflammatory Monocytes Are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii

(2008) Ildiko R. Dunay et al.   IMMUNITY

Unique CD14+ intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-γ axis

(2008) Nobuhiko Kamada et al.   JOURNAL OF CLINICAL INVESTIGATION

Blocking TNF-α in mice reduces colorectal carcinogenesis associated with chronic colitis

(2008) Boryana K. Popivanova et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages

(2008) Santhakumar Manicassamy et al.   SEMINARS IN IMMUNOLOGY