Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling

Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages

(2016) Lianne van de Laar et al.   IMMUNITY

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

The development and maintenance of resident macrophages

(2016) Elisa Gomez Perdiguero et al.   NATURE IMMUNOLOGY

Tissue biology perspective on macrophages

(2016) Yasutaka Okabe et al.   NATURE IMMUNOLOGY

Extensive local adaptation within the chemosensory system following Drosophila melanogaster’s global expansion

(2016) J. Roman Arguello et al.   Nature Communications

IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine

(2016) Mathilde J.H. Girard-Madoux et al.   Oncotarget

TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers

(2016) Penny E. Morton et al.   Scientific Reports

Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells

(2015) Jianpeng Sheng et al.   IMMUNITY

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

(2015) Guillaume Hoeffel et al.   IMMUNITY

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

(2015) Kenichi Asano et al.   Nature Communications

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction

(2014) Timo Heidt et al.   CIRCULATION RESEARCH

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

(2014) Dror S. Shouval et al.   IMMUNITY

Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis

(2014) Ehud Zigmond et al.   IMMUNITY

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival

(2014) Emmanuel L. Gautier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Progressive replacement of embryo-derived cardiac macrophages with age

(2014) Kaaweh Molawi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages

(2014) Christoph Schneider et al.   NATURE IMMUNOLOGY

Differentiation of CD11c+CX3CR1+ cells in the small intestine requires Notch signaling

(2014) C. Ishifune et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

(2014) M. Rosas et al.   SCIENCE

Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin

(2013) Samira Tamoutounour et al.   IMMUNITY

Minimal Differentiation of Classical Monocytes as They Survey Steady-State Tissues and Transport Antigen to Lymph Nodes

(2013) Claudia Jakubzick et al.   IMMUNITY

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

(2013) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks

(2013) Michaël Chopin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The nuclear receptor LXRα controls the functional specialization of splenic macrophages

(2013) Noelia A-Gonzalez et al.   NATURE IMMUNOLOGY

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

Negative regulatory receptors of the IL-1 family

(2013) Cecilia Garlanda et al.   SEMINARS IN IMMUNOLOGY

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis

(2012) Thomas Bauer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammation switches the differentiation program of Ly6Chimonocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon

(2012) Aymeric Rivollier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

(2012) Samuel Huber et al.   NATURE

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina

(2012) L. Ruggiero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

(2012) Namiko Hoshi et al.   Nature Communications

Loss of Interleukin-10 or Transforming Growth Factor β Signaling in the Human Colon Initiates a T-Helper 1 Response Via Distinct Pathways

(2011) Anne Jarry et al.   GASTROENTEROLOGY

CD200 receptor and macrophage function in the intestine

(2011) Calum C. Bain et al.   IMMUNOBIOLOGY

The Novel Costimulatory Programmed Death Ligand 1/B7.1 Pathway Is Functional in Inhibiting Alloimmune Responses In Vivo

(2011) J. Yang et al.   JOURNAL OF IMMUNOLOGY

TGF-β2 Suppresses Macrophage Cytokine Production and Mucosal Inflammatory Responses in the Developing Intestine

(2010) Akhil Maheshwari et al.   GASTROENTEROLOGY

Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10

(2010) Yoshiyasu Ueda et al.   INTERNATIONAL IMMUNOLOGY

Inflammation Anergy in Human Intestinal Macrophages Is Due to Smad-induced IκBα Expression and NF-κB Inactivation

(2010) Lesley E. Smythies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF-  Is Required To Maintain the Pool of Immature Langerhans Cells in the Epidermis

(2010) J. M. Kel et al.   JOURNAL OF IMMUNOLOGY

An Independent Subset of TLR Expressing CCR2-Dependent Macrophages Promotes Colonic Inflammation

(2010) A. M. Platt et al.   JOURNAL OF IMMUNOLOGY

Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions

(2009) Chen Varol et al.   IMMUNITY

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE