Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling

Contribution of Anoctamins to Cell Survival and Cell Death

(2019) Karl Kunzelmann et al.   Cancers

Anoctamin 8 tethers endoplasmic reticulum and plasma membrane for assembly of Ca2+ signaling complexes at the ER/PM compartment

(2019) Archana Jha et al.   EMBO JOURNAL

TMEM16F/Anoctamin 6 in Ferroptotic Cell Death

(2019) Jiraporn Ousingsawat et al.   Cancers

Known structures and unknown mechanisms of TMEM16 scramblases and channels

(2018) Maria E. Falzone et al.   JOURNAL OF GENERAL PHYSIOLOGY

Lipid rafts are essential for release of phosphatidylserine-exposing extracellular vesicles from platelets

(2018) Hao Wei et al.   Scientific Reports

Anoctamin-6 regulates ADAM sheddase function

(2018) Martin Veit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Differential effects of anoctamins on intracellular calcium signals

(2017) Inês Cabrita et al.   FASEB JOURNAL

Characterization of the scrambling domain of the TMEM16 family

(2017) Sayuri Gyobu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Executive and Attentional Disorders, Epilepsy and Porencephalic Cyst in Autosomal Recessive Cerebellar Ataxia Type 3 Due to ANO10 Mutation

(2016) Ludivine Chamard et al.   EUROPEAN NEUROLOGY

Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage

(2016) Nadine J. A. Mattheij et al.   FASEB JOURNAL

Unknown

(2015) Christian Hammer et al.   MOLECULAR MEDICINE

Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages

(2015) Jiraporn Ousingsawat et al.   Nature Communications

Identification and characterization of ANO9 in stage II and III colorectal carcinoma

(2015) Chunxiang Li et al.   Oncotarget

Identification of a lipid scrambling domain in ANO6/TMEM16F

(2015) Kuai Yu et al.   eLife

ANO10 mutations cause ataxia and coenzyme Q10 deficiency

(2014) Andrea Balreira et al.   JOURNAL OF NEUROLOGY

Activation of Ca2+-activated Cl−channel ANO1 by localized Ca2+signals

(2014) Xin Jin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Role of anoctamins in cancer and apoptosis

(2014) P. Wanitchakool et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Role of Membrane Microdomains in Compartmentation of cAMP Signaling

(2014) Shailesh R. Agarwal et al.   PLoS One

Mid-range Ca2+ signalling mediated by functional coupling between store-operated Ca2+ entry and IP3-dependent Ca2+ release

(2014) Raphaël Courjaret et al.   Nature Communications

Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst–forming epithelial cells

(2013) Bjoern Buchholz et al.   KIDNEY INTERNATIONAL

Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase?

(2013) Karl Kunzelmann et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Anoctamins are a family of Ca2+-activated Cl- channels

(2012) Y. Tian et al.   JOURNAL OF CELL SCIENCE

Expression and function of epithelial anoctamins

(2011) Karl Kunzelmann et al.   EXPERIMENTAL PHYSIOLOGY

Anoctamins

(2011) Karl Kunzelmann et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The human P2X7 receptor and its role in innate immunity

(2011) J. S. Wiley et al.   TISSUE ANTIGENS

Targeted Next-Generation Sequencing of a 12.5 Mb Homozygous Region Reveals ANO10 Mutations in Patients with Autosomal-Recessive Cerebellar Ataxia

(2010) Sascha Vermeer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recessive Mutations in the Putative Calcium-Activated Chloride Channel Anoctamin 5 Cause Proximal LGMD2L and Distal MMD3 Muscular Dystrophies

(2010) Véronique Bolduc et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

(2010) Wan Namkung et al.   FASEB JOURNAL

Expression and Function of Epithelial Anoctamins

(2010) Rainer Schreiber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological properties of a pore induced by raising intracellular Ca2+

(2009) R.X. Faria et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A signal comprising a basic cluster and an amphipathic  -helix interacts with lipids and is required for the transport of Ist2 to the yeast cortical ER

(2009) K. Maass et al.   JOURNAL OF CELL SCIENCE

The challenge of lipid rafts

(2008) Linda J. Pike   JOURNAL OF LIPID RESEARCH